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When a vaccine is approved, who will get it? How will it get to them?Johns Hopkins has a plan to make front line workers and those most vulnerable first in line. Other experts say that may not be the best approach.“It may be better to immunize people who are at high risk of transmitting the virus both because of jobs, living situations and other circumstances,” said Dr. Ezekiel Emanuel while speaking with the head of the Journal of the American Medical Association. “And that I think we have to leave an open mind and look at some detailed modeling about what the best way is to reduce the premature mortality.”Emanuel says transmission between health care workers and patients is basically zero where he is. He says effective PPE use is the reason.The groups Johns Hopkins said should get a vaccine first could be as big as 90 million people.Emanuel says there won't be enough doses out of the gate to get all of any initial groups.“You don’t actually distribute it evenly among countries,” he said. “You concentrate on countries that at the moment when you have the vaccine have severe hot spots and where the vaccine is going to make the biggest difference in terms of reducing premature death.”Johns Hopkins experts say a vaccine's effectiveness is measured on preventing disease. That doesn't mean it prevents infection and transmission. We won’t know how effective it will be until after it’s in use.“A disease transmission strategy makes a lot of sense, but we need a lot more information before we can know who to prioritize,” said Dr. Eric Toner, a senior scholar at the Johns Hopkins Center for Health Security. “It’s quite possible we will go to a strategy like that.”The World Health Organization said younger people in their 20s, 30s and 40s are increasingly driving spread.The first vaccines will likely be two doses. Experts say that means double the syringes, needles, vials and other supplies, along with getting people to come back for a second dose. 1980

Whole Foods is getting even more Amazon-y.Amazon, which purchased Whole Foods last year, is offering its Prime members an additional 10% off sale items when they shop at Whole Foods.The additional discount will apply to hundreds of products throughout the stores. To get the discount, Prime members will have to scan the Whole Foods app at checkout, after signing into the app with their Prime membership.Earlier this year, the companies launched free two-hour delivery on Whole Foods groceries in 10 test cities, through Amazon's Prime Now service. Amazon expects to expand that offering later this year. Eligible Prime members also receive 5% back on Whole Foods purchases when using the Amazon Prime Visa card.Amazon now has more than 100 million Prime members. It also announced it would raise the annual cost of membership by 20% to 9 a year, from .Amazon cut prices at Whole Foods for all customers once it completed its purchase of the chain in August, and announced another round of price cuts in November.  1034

WINDSOR, N.C. — At least six people were killed as Tropical Storm Isaias spawned tornadoes and dumped rain Tuesday along the U.S. East Coast after making landfall as a hurricane in North Carolina, where it caused floods and fires that displaced dozens of people.Two people died when Isaias spun off a tornado that struck a North Carolina mobile home park. Another person died in Pennsylvania when their vehicle was overtaken by water and swept downstream. Two others were killed by falling trees toppled by the storm in Maryland and New York City, and a sixth person died in Delaware when a tree branch fell on them, authorities said.Isaias sustained top winds of up to 65 mph more than 18 hours after coming ashore, but it was down to 45 mph max winds as of 10:50 p.m. EDT Tuesday, according to the National Hurricane Center. The storm's center was about 45 miles southeast of Montreal, moving northeast into Canada at about 38 mph.As Isaias sped northward, flooding threats followed. The Schuylkill River in Philadelphia was projected to crest early Wednesday at 15.4 feet, its highest level in more than 150 years. By Tuesday night, the river had already topped its banks in low-lying Manayunk, turning bar-lined Main Street into a coffee-colored canal.Aerial video by WRAL-TV showed fields of debris where rescue workers in brightly colored shirts picked through splintered boards and other wreckage of the Windsor, North Carolina, mobile home park where two people were killed. Emergency responders searching the area Tuesday afternoon found no other casualties, and several people initially feared missing had all been accounted for, said Ron Wesson, chairman of the Bertie County Board of Commissioners. He said about 12 people were hospitalized.“It doesn’t look real; it looks like something on TV. Nothing is there,” Bertie County Sheriff John Holley told reporters, saying 10 mobile homes had been destroyed. “All my officers are down there at this time. Pretty much the entire trailer park is gone.”In eastern Pennsylvania, a 44-year-old Allentown woman was killed after encountering high waters on a street in Upper Saucon Township that swept her vehicle downstream Tuesday afternoon, the Lehigh County coroner’s office said.While in New York City, a massive tree fell and crushed a van in the Briarwood section of Queens, killing Mario Siles, a 60-year-old construction contractor who was inside the vehicle, police said. A woman in Mechanicsville, Maryland, died when a tree crashed onto her car during stormy conditions, said Cpl. Julie Yingling of the St. Mary’s County sheriff’s office.In Delaware, authorities said a woman was outside assessing storm damage when she was hit and killed by a falling tree branch.Isaias toggled between hurricane and tropical storm strength as it churned toward the East Coast. Fueled by warm ocean waters, the storm got a late burst of strength as a rejuvenated hurricane with top sustained winds of 85 mph before coming ashore late Monday near Ocean Isle Beach, North Carolina. Its tropical storm status was sustained, but weakened, as it headed north into Canada on Tuesday night.Before making landfall late Monday, Isaias killed two people in the Caribbean and battered the Bahamas before brushing past Florida.Tornadoes were confirmed by the National Weather Service in Virginia, Maryland, Delaware and New Jersey. Power outages also spread as trees fell, with more than 3.7 million customers losing electricity across multiple states as of 10:15 p.m. EDT Tuesday, according to PowerOutage.US, which tracks utility reports. New York City's power utility said it saw more outages from Isaias than from any storm except Superstorm Sandy in 2012.In Doylestown, Pennsylvania, officials said four children were treated for minor injuries after high winds partially tore the roof off a day care center. Also in the Philadelphia suburbs, rescue workers in Delaware County were searching for a young person who fell or jumped into the fast-moving water of a swollen creek, said Timothy Boyce, the county emergency services director.In New York City, fierce wind and rain forced the Staten Island ferry and outdoor subway lines to shut down. The New Jersey Turnpike banned car-pulled trailers and motorcycles.Some of the worst damage Tuesday seemed to be east and north of where the hurricane’s eye struck land in North Carolina.“Fortunately, this storm was fast-moving and has already left our state," Gov. Roy Cooper said Tuesday afternoon.In North Myrtle Beach, South Carolina, the storm sent waves crashing over the Sea Cabin Pier late Monday, causing a big section to collapse into the water as startled bystanders taking photos from the pier scrambled back to land.“I'm shocked it's still standing,” said Dean Burris, who watched from the balcony of a vacation rental.The Hurricane Center had warned oceanside dwellers near the North Carolina-South Carolina state line to brace for storm surge up to 5 feet and up to 8 inches of rain.Eileen and David Hubler were out early Tuesday cleaning up in North Myrtle Beach, where 4 feet (1.2 meters) of storm surge flooded cars, unhinged docks and etched a water line into the side of their home.“When the water started coming, it did not stop,” Eileen Hubler said. They had moved most items of value to their second floor, but a mattress and washing machine were unexpected storm casualties.“We keep thinking we’ve learned our lesson,” she said. “And each time there’s a hurricane, we learn a new lesson.” 5507

With his spring break just hours away, Central Michigan University student James Eric Davis Jr. was with his parents in a campus residence hall Friday morning when he shot them dead, police say.Davis Jr., 19, shot and killed his mother and father in the dorm on the northwestern edge of campus Friday morning, authorities said, leading to an hours-long manhunt that ended with his arrest early Saturday.It was the nation's 12th school shooting this year.It's not immediately clear what led to the shooting or why the parents, James Eric Davis Sr., 48, and Diva Jeenen Davis, 47, were on campus in Mount Pleasant, a roughly four-hour drive from their Chicago-area home.But authorities said the student had an encounter with police hours earlier -- on Thursday evening when he was taken to a hospital for what officers believed was a bad reaction to drugs, campus police Lt. Larry Klaus said.And the parents may have been intending to pick up their son for spring break, said Andre Harvey, mayor of the Chicago suburb of Bellwood, where the elder Davis was a part-time officer."The family is in shock and trying to piece everything together," a relative, speaking on condition of anonymity, told CNN.Arrest comes after midnightDetails about the younger Davis' arrest weren't immediately clear. But it came early Saturday after someone reporting seeing him on or near campus, the university said."The suspect was seen and reported by an individual on a train passing through the north end of campus shortly after midnight," the university said in an online statement. "Law enforcement personnel responded and arrested the suspect without incident."The shooting, which happened on Campbell Hall's fourth floor around 8:30 a.m. Friday, disrupted a campus that otherwise was winding down for a nine-day spring recess beginning Saturday.Students were told to stay in campus buildings until the afternoon when police officers started allowing them to leave. People trying to enter the campus to pick up students for spring break were initially directed to a campus-area hotel, where the university asked them to wait for instructions.The university's men's basketball home game Friday against Western Michigan University was rescheduled for Saturday morning at a neutral site, Northwood University, where it will be closed to the public except for family members, the Mid-American Conference said.The university, with roughly 23,000 students, is about a two-hour drive northwest of Detroit.Student had 'drug-related' incident earlier, police sayCampus police spoke with Davis Jr. on Thursday night, Klaus said during a news conference."At some point in the evening, he was transported to McLaren Hospital due to what the officers believed may be a drug-related-type incident, an overdose or a bad reaction to drugs. At that point he was released to the hospital staff," Klaus said.As for Friday's shooting, "we're calling it a family-type domestic issue at this point," he said.The victimsThe Davis family was from the Chicago area. Davis Jr. graduated from a high school in Plainfield, Illinois, about 30 miles southwest of Chicago, in 2016, said Tony Hernandez, Plainfield school district spokesman.His father was a part-time police officer in Bellwood for 20 years and assisted the department on special occasions."He was always there when you asked for him to be there," Bellwood police Chief Jiminez Allen said.The elder Davis was a pillar of the community, which has 20,000 residents, and was beloved by friends and neighbors, said Harvey, Bellwood's mayor.An Army veteran, he was also a police officer employed at the Jesse Brown VA Medical Center in Chicago, said center director Marc Magill."The staff at Jesse Brown VAMC take enormous pride in the care we provide our Veterans, and this situation hits us especially hard. We are currently providing grief counseling for staff," Magill said.The violence came more than two weeks after a shooting rampage at Marjory Stoneman Douglas High School in Parkland, Florida, left 17 people dead and spurred a national debate over gun control.Nine weeks into the year and 12 school shootingsCNN's calculation of the number of school shootings include shootings on school property that involve one or more victims and other factors. These can also be domestic violence incidents.The-CNN-Wire? & ? 2018 Cable News Network, Inc., a Time Warner Company. All rights reserved. 4423

White House officials said Monday that the Trump administration is pursuing another legislative push on immigration, but when pressed said the effort would largely be the same as it has been trying unsuccessfully since last fall.The comments came in a call on Monday with reporters organized to back up a string of tweets from President Donald Trump over the weekend and into Monday pushing a hard line on immigration, sounding off on the Deferred Action for Childhood Arrivals policy, illegal immigration and Mexico.The call, held on the condition the speakers not be quoted by name, largely re-hashed the administration's talking points on immigration, calling provisions of US and international immigration law "loopholes" that human smugglers misconstrue to encourage would-be migrants to make the journey to the US. 838