昌吉用试纸测出第二条线很浅(昌吉怀孕20天能做药流吗) (今日更新中)

WASHINGTON, Aug. 2 (Xinhua) -- The weakness of aging is associated with leaky calcium channels inside muscle cells and a drug already in Phase II clinical trials for the treatment of heart failure might plug those leaks, according to a report published Tuesday in the online edition of Cell Metabolism.Earlier studies by the research team led by Andrew Marks of Columbia University showed the same leaks underlie the weakness and fatigue that come with heart failure and Duchenne muscular dystrophy."It's interesting, normal people essentially acquire a form of muscular dystrophy with age," Marks said. "The basis for muscle weakness is the same." Extreme exercise like that done by marathon runners also springs the same sort of leaks, he added, but in that case damaged muscles return to normal after a few days of rest. A microscopic view shows smooth muscle cells derived from human embryonic stem cells showing the nuclei (blue) and proteins of the cytoskeleton (green) in this handout photo released to Reuters by the California Institute for Regenerative Medicine, March 9, 2009The leaks occur in a calcium release channel called ryanodine receptor 1 (RyR1) that is required for muscles to contract. Under conditions of stress, those channels are chemically modified and lose a stabilizing subunit known as calstabin1.Calcium inside of muscle cells is usually kept contained. When it is allowed to leak out into the cell that calcium itself is toxic, turning on an enzyme that chews up muscle cells. Once the leak starts, it's a vicious cycle. The calcium leak raises levels of damaging reactive oxygen species, which oxidize RyR1 and worsen the leak.The researchers made their discovery by studying the skeletal muscles of young and old mice. They also showed that 6-month-old mice carrying a mutation that made their RyR1 channels leaky showed the same muscular defects and weakness characteristic of older mice.When older mice were treated with a drug known as S107, the calcium leak in their muscles slowed and the animals voluntarily showed about a 50 percent increase in the amount of time spent wheel running. Now in clinical trials for patients with heart failure, the drug is known to work by restoring the connection between costabilin and RyR1.Despite considerable effort to understand and reverse age- related muscle wasting, there are no established treatments available. The new work suggests there may be hope in approaching the problem from a different angle."Most research has focused on making more muscle mass," Marks said. "What's different here is that we are focused not on muscle mass but on muscle function. More muscle doesn't help if it is not functional."

SAN FRANCISCO, July 20 (Xinhua) -- Google announced on Wednesday that it has reached a deal with author J.K. Rowling to launch the series of Harry Potter ebooks on Google's platform.When the series of Harry Potter ebooks launch on Pottermore.com in early October, the bestsellers will be available in the United States via Google eBooks platform, said Google in a blog post.When customers buy a Harry Potter ebook from Pottermore.com, they will be able to choose to keep it in their Google's online library in the cloud, as well as other e-reading platforms.Google said Google eBooks can be read on most devices with a modern browser, through Google apps for iOS and Android smartphones and tablets, and on more than 80 e-readers.Meanwhile, Rowling will continue to issue announcements via YouTube, as she announced Pottermore.com in June.The two sides also agreed to make Google Checkout the preferred third-party payment platform for all purchases made on Rowling's Pottermore.com.Pottermore.com, which will be launched on July 31, will sell ebook and audiobook versions of the seven Harry Potter novels, as well as additional content including background details and settings.According to The Times, the Harry Potter brand value is estimated to be more than 15 billion U.S. dollars. The deal could make Google move some e-reader customers from competitors like Amazon, whose e-reader Kindle does not support Google eBooks.

BERLIN, Aug. 28 (Xinhua) -- Mercedes-Benz, the world leading luxury car producer, celebrates the 125th anniversary of its invention of automobile with what it claimed the largest gathering ever, at the former Tempelhof airport in Berlin on the weekend.The Mercedes-Benz Club and Mercedes-Benz enthusiasts greet visitors with some 1,800 well-assorted Mercedes-Benz-branded vehicles, ranging from vintage and classic passenger cars to a variety of historic commercial vehicles, on a vast open areas of 250,000 square metres of the abandoned Tempelhof airport, which was closed in 2008.It took Mr. Lauritzen and his wife two days' drive of their cherised wecker of Mercedes-Benz Cabriolet B. 320.W 142.-3,4l to reach here for taking part in the pageant."It is a long journey, but we are happy to be here to see more class cars and more friends with same interests," Mrs Lauritzen said.Owners take the opportunity to present their lovingly cared-for vehicles, which include a number of truly rare items of automotive history, to the Berlin public.The couple of Mr. Kerner drove their red Mercedes-Benz 170Dba, a made-in-1952 model with a range of special and unique designs which are very rarely seen now, over journey of 155 km from Bitterfeld to join in the gala."I'm fond of driving my classic car of Benz," said Mrs Kerner, despite it can run maximally at a speed of 50 to 80 km per hour, "but I truly enjoy the diesel engine sounds and the historic feeling it evokes."The legendary Silver Arrows, dating from the 1930s and 1950s, are also presented from the Mercedes-Benz Classic collection for demonstration drives."The brilliant history of the Silver Arrows will be brought to life with a demonstration of their impressive engine sound and incredible driving dynamics," said Michael Bock, head of Mercedes-Benz Classic and Director of Mercedes-Benz Museum GmbH."It is not often that these racing cars are driven in public, so this will be a true highlight of the program of events in Tempelhof."During the grand show, visitors are also accessible to first-hand experiences of the latest technologies applicable in the future for in passenger cars, commercial vehicles and racing cars."Some 125 years ago, Carl Benz submitted his patent application for the Benz Patent Motor Car to the Patent Office in Berlin", the organizer appealed to the visitors, saying now Mercedes-Benz is returning to Berlin to celebrate together with Berliners.

SAN FRANCISCO, Sept. 27 (Xinhua) -- Apple on Tuesday announced an invitation-only special event featuring iPhone on Oct. 4, 2011.With a simple headline reading "Let's talk iPhone," the invitation said that there will be an "executive presentation at 10 a.m.." This could be the first big product introduction by the newly installed Chief Executive Officer Tim Cook after he took over the reins of Apple from Steve Jobs in August.The event, which will be held at Apple campus in Cupertino, California, has long been reported to be the introduction of iPhone 5, the next generation iPhone.According to U.S. media reports, the iPhone 5 is expected to have revamped hardware design with a larger screen, a higher resolution camera and a faster dual-core A5 chip on which the iPad 2 runs. Apple is also reported to release a low-cost and contract- free iPhone model bundled with its cloud computing service iCloud.

SAN FRANCISCO, Sept. 9 (Xinhua) -- AOL's chief executive officer (CEO) Tim Armstrong has reached out to Yahoo for talks of a merger of the two companies, U.S. media reported on Friday.Armstrong is discussing options for a combination aimed at strengthening the two Internet companies, Bloomberg quoted two people who are familiar with the matter as saying.The report said that the AOL CEO had been interested in a merger with Yahoo last year but was rejected while Carol Bartz served as Yahoo CEO, who was ousted by Yahoo's board on Tuesday.Reconsidering the option after Bartz's departure, Armstrong has talked with private equity firms and investment bankers from Allen & Co. working with Yahoo.Under one scenario being considered, Yahoo would acquire AOL and Armstrong would become CEO of the combined company, said the source.Both Yahoo and AOL are suffering from declining revenues, struggling to compete against companies like Google and Facebook. Some analysts said that the merger could not provide a long-term solution to the problems the two companies face after they failed to keep up with Internet trends.

来源：资阳报