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ISLAMABAD, Oct. 24 (Xinhua) -- Samina, 38, was shocked when doctor told her that she has been suffering from breast cancer for three years and due to late diagnosis the disease spread into her bones making the chances of survival very slim.Samina said that she is trying hard to fight the disease, at the same time she holds the doctors of her village responsible for failing to diagnose the disease in three long years. She is also concerned about her three kids too young to accept any bitter reality."I can't see the distressed faces of my children, I can't bear the fear that looms in their eyes, they know that with every coming day their mother is moving a step forward to death," Samina told Xinhua in a very low tone.When Samina and all other patients of that gloomy medical ward for breast cancer patients, in Nuclear Medicine Oncology and Radiography (NORI) hospital in Islamabad, were told that October is being observed as breast cancer awareness month they murmured that the awareness message should be reached to every nook and corner of the country this year so that no other woman would die due to unawareness.In a country like Pakistan where one in nine women is prone to breast cancer and around 40,000 women die every year due to lack of awareness of this disease. They come to visit oncology department of hospitals at a stage when the chances of survival are very remote.Omer Aftab, National Coordinator of the Pink Ribbon, said that Pakistan has the highest rate of breast cancer among Asian nations. It is the most common malignancy in women, and accounts for 38.5 percent of all female cancer patients, with 90,000 new cases every year.

BEIJING, Dec. 24 (Xinhua) -- A senior Chinese official has urged to improve work in the country's judicial administrative departments.Zhou Yongkang, a member of the Standing Committee of the Political Bureau of the CPC Central Committee, made the remarks at a meeting honoring excellent individuals and collectives in the judicial administrative sector in the past five years.Zhou commended the contributions that the judicial administrative departments have made to social stability, the building of socialist legal system, and the development of the society and economy, asking those being honored to make persistent efforts to serve the people.Zhou urged the judicial administrative organs at all levels to make new progress in serving the development by enhancing law awareness and providing high quality legal services.He also called for building grassroots mediation organizations that people can rely on, in order to resolve disputes in the grassroots and nip them in the bud.Labor education and rehabilitation in jails, as well as the community rehabilitation programs that can help law offenders successfully return and reintegrate into society, should be further improved, Zhou said, adding that it will also help enhance the social harmony by preventing repeated crimes.

WASHINGTON, Jan. 19 (Xinhua) -- New research published this week in Nature Medicine indicates that targeted drugs such as gefitinib might more effectively treat non-small cell lung cancer if they could be combined with agents that block certain microRNAs.The study, led by investigators with the Ohio State University Comprehensive Cancer Center, shows that overexpression of two genes called MET and EGFR causes the deregulation of six microRNAs, and that this deregulation leads to gefitinib resistance.The findings support the development of agents that restore the levels of these microRNAs. It offers a new strategy for treating non-small cell lung cancer, which is responsible for about 85 percent of the 221,000 lung-cancer cases and 157,000 deaths that occur annually in the United States. It also suggests that measuring the expression levels of certain microRNAs -- those controlled by the MET gene -- might predict which lung-cancer cases are likely to be resistant to gefitinib.Epidermal growth factor receptor (EGFR) is frequently overexpressed in non-small cell lung cancer, and this leads to uncontrolled cell proliferation. Gefitinib selectively inhibits EGFR activation and triggers cancer cells to self-destruct by apoptosis. However, non-small cell lung cancer cells inevitably develop resistance to the drug. The study reveals how this resistance occurs."Our findings suggest that gefitinib resistance that is caused by MET overexpression is at least partly due to miRNA deregulation, " says principal investigator Carlo Croce.

BEIJING, Nov. 9 (Xinhua) -- A Chinese Mars orbiter named Yinghuo-1 was successfully launched on Wednesday morning from Russian-leased Baikonur cosmodrome in Kazakhstan, China's authorities said. The orbiter was launched by a Zenit-2 booster rocket at 4:16 a.m. Beijing time Wednesday (2016 GMT Tuesday), hitching a ride on Russia's Phobos-Grunt (Phobos-Soil) craft, an unmanned probe on Phobos, a moon of Mars, said China's State Administration for Sciences, Technology, and Industry for National Defence.

WASHINGTON, Nov. 24 (Xinhua) -- A new study suggests that the rate of global warming from doubling of atmospheric carbon dioxide may be less than the most dire estimates of some previous studies.Authors of the study, which was funded by the National Science Foundation and published online on Thursday in the journal Science, say that global warming is real and that increases in atmospheric CO2 will have multiple serious impacts. However, the most Draconian projections of temperature increases from the doubling of CO2 are unlikely."Many previous climate sensitivity studies have looked at the past only from 1850 through today, and not fully integrated paleoclimate date, especially on a global scale," said Andreas Schmittner, an Oregon State University researcher and lead author on the Science article. "When you reconstruct sea and land surface temperatures from the peak of the last Ice Age 21,000 years ago -- which is referred to as the Last Glacial Maximum -- and compare it with climate model simulations of that period, you get a much different picture.""If these paleoclimatic constraints apply to the future, as predicted by our model, the results imply less probability of extreme climatic change than previously thought," Schmittner added.Scientists have struggled for years trying to quantify "climate sensitivity" -- which is how the Earth will respond to projected increases of atmospheric carbon dioxide. The 2007 IPCC report estimated that the air near the surface of the Earth would warm on average by two to 4.5 degrees (Celsius) with a doubling of atmospheric CO2 from preindustrial standards. The mean, or " expected value" increase in the IPCC estimates was 3.0 degrees; most climate model studies use the doubling of CO2 as a basic index.The researchers based their study on ice age land and ocean surface temperature obtained by examining ices cores, bore holes, seafloor sediments and other factors. When they first looked at the paleoclimatic data, the researchers only found very small differences in ocean temperatures then compared to now."Our study implies that we still have time to prevent that from happening, if we make a concerted effort to change course soon," said Schmittner.