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SAN FRANCISCO, Nov. 1 (Xinhua) -- Yahoo, which has been rumored to sell all or part of its business, announced on Tuesday that it is buying data-driven advertising network Interclick for around 270 million U.S. dollars.Interclick is a technology company providing data targeted solutions and optimization technologies."This investment underscores our focus on enhancing the performance of both our guaranteed and non-guaranteed display business across Yahoo and our partner sites and, combined with Yahoo's reach and advertising leadership, will deliver a powerful solution for marketers," said Ross Levinsohn, Yahoo's executive vice president for the Americas region.Some analysts said Interclick's technology could help Yahoo to grow its display advertising market share as Google and Facebook have gained on or surpassed the company in the area.But the acquisition also raised questions considering Yahoo's financial situation after it reported last month its revenue in the last quarter decreased by 5 percent year-over-year. The company is also in a chief executive officer (CEO) search following the firing of former CEO Carol Bartz in September and amidst reports of a possible takeover.Although in a financial struggle, Yahoo still has around 700 million unique monthly visitors and its news division is the biggest online news site with around 81.2 million unique visitors in August.Tech giants like Google and Microsoft are reported to be considering providing finance for the acquisition of Yahoo by another company or a group of companies.In a report on Monday, Bloomberg News reported that Yahoo is leaning toward selling Asian assets and redistributing the proceeds to shareholders, rather than selling itself to a group of buyers. Yahoo's shares fell more than 5 percent after the possibility was reported.
WASHINGTON, Dec. 12 (Xinhua) -- British scientists have discovered a new way to target cancer through manipulating a master switch responsible for cancer cell growth. The findings, published Monday in the U.S. journal Cancer Cell, reveal how cancer cells grow faster by producing their own blood vessels.Cancer cells gain the nutrients they need by producing proteins that make blood vessels grow, helping deliver oxygen and sugars to the tumor. These proteins are vascular growth factors like VEGF -- the target for the anti-cancer drug Avastin. Making these proteins requires the slotting together of different parts of genes, a process called splicing.Scientists at the University of West England and the University of Bristol discovered that mutations in one specific cancer gene can control how splicing is balanced, allowing a master switch in the cell to be turned on. This master switch of splicing makes cancer cells grow faster, and blood vessels to grow more quickly, as they alter how VEGFs are put together.In experimental models, the researchers found that by using new drugs that block this master switch they prevented blood vessel growth and stopped the growth of cancers."The research clearly demonstrates that it may be possible to block tumor growth by targeting and manipulating alternative splicing in patients, adding to the increasingly wide armory of potential anti-cancer therapies," the authors said.
JERUSALEM, Oct. 24 (Xinhua) -- A recent study carried out by Israeli researchers showed that the experience of motherhood is caused by alterations in the brain functions that help mothers locate and communicate with their offspring, especially if they are in distress.Researchers at the Hebrew University of Jerusalem said the results provide insight into how neural changes in response to odors and sounds help maternal behaviors develop in mothers."We know that distinct brain changes are linked with motherhood, " Dr. Adi Mizrahi, who conducted the research, said, "but the impact of these changes on sensory processing and the emergence of maternal behaviors are largely unknown."Mizrahi and his colleagues examined whether the primary auditory cortex -- a region in the brain that is involved in the recognition of sounds -- might serve to process the responses to their offspring's specific smell and voice.The research proved that the olfactory and auditory senses of female mice with their pups were triggered immediately after they gave birth, with especially strong responses to cries of distress."These processes help to explain how changes in the cortex in the brain facilitate efficient detection of pups," Mizrahi said.
WASHINGTON, Nov. 18 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday revoked its approval of Avastin for treating the breast cancer after concluding that the drug has not been shown to be safe and effective for that use.Avastin will still remain on the market as an approved treatment for certain types of colon, lung, kidney and brain cancer."After reviewing the available studies it is clear that women who take Avastin for metastatic breast cancer risk potentially life-threatening side effects without proof that the use of Avastin will provide a benefit, in terms of delay in tumor growth, that would justify those risks," FDA Commissioner Margaret Hamburg said in a statement. "Nor is there evidence that use of Avastin will either help them live longer or improve their quality of life. "Avastin's risks include severe high blood pressure; bleeding and hemorrhaging; heart attack or heart failure; and the development of perforations in different parts of the body such as the nose, stomach, and intestines.Avastin was approved for metastatic breast cancer in February 2008 under the FDA's accelerated approval program, which allows a drug to be approved based on data that are not sufficiently complete to permit full approval. After the approval, the drug's sponsor, Genentech, completed two additional clinical trials and submitted the data from those studies to the FDA. These data showed only a small effect on tumor growth without evidence that patients lived any longer or had a better quality of life compared to taking standard chemotherapy alone -- not enough to outweigh the risk of taking the drug.FDA's Center for Drug Evaluation and Research, which is responsible for the approval of this drug, ultimately concluded that the results of these additional studies did not justify continued approval and notified Genentech it was proposing to withdraw approval of the indication.Genentech did not agree with the Center's evaluation of the data and, following the procedures set out in FDA regulations, requested a hearing on the Center's withdrawal proposal, with a decision to be made by the Commissioner. That two-day hearing, which took place June 28-29, included recommendations from the FDA 's Oncologic Drugs Advisory Committee, voting 6-0 in favor of withdrawing approval of Avastin's breast cancer indication.
BEIJING, Jan. 8 (Xinhua) -- China canceled over one-third of all official ceremonies, seminars and forums last year in a bid to avoid extravagance or corruption in the use of public resources.Some 2,549 such activities proposed by governments or public institutions, or 37.7 percent of the total applications, which were deemed "ceremonial" and "unnecessary," were cut, saving 1.22 billion yuan (about 193.39 million U.S. dollars), said an official statement released Sunday.The statement was issued by the State Council's Office for Rectifying Malpractices, a ministry-level inter-agency supervisory body dedicated to eliminating administrative irregularities and abuse of power in government agencies, public institutions and major service sectors.Last year's inspections focused on activities co-funded by ministries and local governments, the statement said.The Chinese government agreed with the public that the soaring number of official celebrations, seminars and forums would cost plenty of money and manpower and exacerbate corrupt behaviors.In March, the State Council, or China's Cabinet, ordered 98 ministries and ministry-level government organs to make public their budgets and expenditures on official overseas visits, public vehicles and official receptions -- the "three public consumptions" that had triggered widespread public concern.Premier Wen Jiabao also repeatedly urged the country's government agencies to reduce administrative expenses, including cutting the number of meetings and documents printed.Official figures indicate that the country's crackdown on various forms of extravagant spending by officials saved the country 5.7 billion yuan in 2010.A blue book on China's conferences published in November estimated that the total output of the country's conference industry had reached nearly 1 trillion yuan. Companies made up half of this total, while a considerable portion came from the government and public institutions compared to other social organizations.