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Johnson & Johnson announced it has paused its coronavirus vaccine trials on Monday following an “unexplained illness” among one of its participants.Johnson & Johnson stressed that adverse events during trials are expected, and a pause gives researchers an opportunity to review all of the medical information before moving forward with the trial. Johnson & Johnson added that it’s not always immediately known if the affected person received a placebo or a study treatment.Among the trials paused was Johnson & Johnson’s multi-country “ENSEMBLE” vaccine, which entered Phase 3 testing in September. Johnson & Johnson said last month that its goal was to seek an emergency use authorization approval in early 2021.The FDA noted that a vaccine candidate must be at least 50% effective to receive emergency use authorization. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.” 1554
KANSAS CITY, Mo. — Missouri lawmakers advanced a bill Wednesday, that would allow concealed carry in churches, daycares and bars, among other locations.House Bill 1936 extends the list of places where gun owners can carry a concealed weapon — whether they have a permit or not."The definition of a criminal is someone who doesn't follow the law. We should be giving an individual the ability to protect themselves in any situation," said state Rep. Jered Taylor, a Republican from Nixa.This is the second year Taylor has introduced this bill.Currently, in Missouri, there are 17 locations where concealed carry is not allowed. Taylor's bill would narrow that list.If passed, the bill would allow concealed carry at amusement parks, casinos, child care facilities, churches, hospitals, stadiums, polling locations and local government buildings, including public universities and colleges."You cannot carry into those locations unless you have express permission from the property owner. What I am trying to do is leave it up to the property owner and let them decide what they want to allow and not allow," said Taylor.To opt out, private businesses would have to post signs prohibiting guns. Government buildings and public universities would not have that option."When I think about gun violence in KC and the legislation that is happening in Jefferson City, there is a huge disconnect," said AdHoc president Damon Daniel.Based on his experiences helping victims of crime, Daniel said he does not believe guns are the solution. In fact, hours before a committee passed HB 1936, he joined the Jackson County prosecutor in announcing a new service to help innocent bystanders of crimes."That's just not the solution. The solution to curb violence in Kansas City, especially when we talk about homicides, is we need more economic opportunities, we need more jobs, more mental health providers," said Damon, who added other than having a gun to protect one's home "no one wants a lot of people walking around carrying guns."Since the bill passed out of a House rules committee, it can be brought for debate on the House floor anytime.To read the bill in its entirety, see the window below. 2195

Jamal Khashoggi's death was pre-planned and was not spontaneous or an accident, Turkey's President Recep Tayyip Erdogan said on Tuesday in a highly anticipated speech, which flat-out denied Saudi Arabia's claim that the journalist's killing was not premeditated."Jamal Khashoggi was the victim of a ferocious murder," Erdogan said, underlining that his killing was not accidental, but meticulously planned. "This kind of brutality is against the collective human conscience."Erdogan also revealed that a Saudi team carried out reconnaissance at two separate locations and cameras and that a hard drive were removed from the kingdom's consulate prior to the journalist's arrival on October 2 for his scheduled appointment."We stated that we would not remain silent and that we would take every step necessary for justice to be done," Erdogan said at a parliamentary address to members of his ruling Justice and Development Party (AKP), two days after promising to reveal "the naked truth" of the Khashoggi case.Erdogan called on the King of Saudi Arabia for the 18 Saudi suspects linked to Khashoggi's death be tried in Istanbul.After weeks of denying any knowledge of Khashoggi's whereabouts, the Saudi government said on Friday that the journalist had indeed died in the kingdom's diplomatic compound in Istanbul. The Saudi story has shifted drastically since Khashoggi was last seen entering the consulate on October 2; the official line is now that he was accidentally killed when a discussion with officials turned into a brawl.Erdogan presented a very different version of events on Tuesday, speaking in Ankara as Saudi Arabia's flagship investment conference got underway in Riyadh, the Saudi capital. Dozens of top business leaders from around the world have pulled out of Crown Prince Mohammed bin Salman's showcase event, known as "Davos in the desert," as questions mount over the Saudi government's role in the death of the Washington Post columnist and US resident.Saudi Foreign Minister Adel al-Jubeir said on Sunday that Khashoggi's killing was part of a rogue operation and that his government would punish those responsible for his "murder."But Turkish officials have maintained from the start that Khashoggi's death was "violently planned" ahead of time, carried out by a team of Saudi operatives dispatched to Istanbul, and subsequently covered up.In the intervening weeks, Turkish officials have released a drip-feed of information related to their investigation into Khashoggi's murder, including surveillance footage shared exclusively with CNN that showed what a Turkish source described as a "body double" leaving the Saudi consulate in Istanbul on the day Khashoggi died. The Saudi operative, said by the Turkish source to be one of a 15-man team sent from Saudi Arabia to kill Khashoggi, was wearing the journalist's clothes and was picked up on surveillance footage at locations around Istanbul.Erdogan confirmed the body double in CNN's exclusive.The Turkish Foreign Minister Mevlut Cavusoglu said Tuesday that evidence uncovered during the investigation has yet to be shared with any country, according to Turkey state-run Anadolu News, but that Turkey was "ready to cooperate in a possible probe into Khashoggi case at UN, international courts.""Jamal Khashoggi's killing is a violently planned and a very complicated murder, which was being covered up," Omer Celik, AKP spokesman, said at the party's headquarters in Ankara on Monday. "I hope those responsible for Khashoggi's killing are punished and no one ever thinks of repeating this."Speaking to reporters on Monday, Erdogan's spokesman Ibrahim Kalin said: "The line our President put since the beginning of this case is very clear. The investigation will continue until the end." 3774
Kanye West will meet with President Donald Trump and his son-in-law Jared Kushner at the White House on Thursday.West will have lunch with the President at the White House and meet with Kushner, according to White House spokeswoman Sarah Sanders. The New York Times first reported news of the meeting.West's visit to the White House falls in line with Kushner's efforts at criminal justice reform. West hopes to discuss two key issues during his visit at the White House: job opportunities for ex-convicts and ways to increase manufacturing jobs in and around his hometown of Chicago. 592
Johnson & Johnson is beginning a huge final-stage study to try to prove if a single-dose COVID-19 vaccine can protect against the virus. It will be one of the world’s largest coronavirus vaccine studies so far, testing in 60,000 volunteers in the U.S., South Africa, Argentina, Brazil, Chile, Colombia, Mexico and Peru. A handful of other vaccines in the U.S. and elsewhere are already in final testing. The two other vaccine candidates in final-phase testing in the U.S. — candidates made by Moderna and Pfizer — were both approved in July. Earlier this month, Dr. Anthony Fauci said those trials should be filled by the end of September, meaning they should be completed by late November or early December.Hopes are high that answers about at least one could come by year’s end, maybe sooner. U.S. health officials insist the race for a vaccine isn’t cutting corners, despite enormous political pressure. 918
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