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WASHINGTON, Nov. 18 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday approved Erwinaze to treat patients with acute lymphoblastic leukemia (ALL), who have developed an allergy to E. coli derived asparaginase and pegapargase chemotherapy drugs used to treat ALL.Acute lymphoblastic leukemia is a type of cancer in which the bone marrow makes too many lymphocytes, a type of white blood cell. White blood cells help the body fight infection and are formed in the bone marrow.Erwinaze is injected directly into the muscle three times a week and works by breaking down one of the body's protein building blocks (the amino acid, asparagine) that is present in the blood, and is necessary for the growth of all cells. Leukemia cells cannot produce this protein building block. When a patient is treated with Erwinaze the leukemia cells die. Normal human cells are able to make enough asparagine for their own needs through biosynthesis and will not be affected by treatment with Erwinaze."The approval of Erwinaze underscores the FDA's commitment to the approval of drugs for conditions with limited patient populations with unmet medical needs using novel trial endpoints," said Richard Pazdur, director of the Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research.Side effects associated with Erwinaze treatment include serious allergic reactions, inflammation of the pancreas, high blood levels of liver enzymes, blood clotting, bleeding, nausea, vomiting and high blood sugar.
BEIJING, Nov. 13 (Xinhua) -- A campaign that aims to boost the public's role in safeguarding food safety and promote awareness of the issue was launched at the 9th China Food Safety Annual Conference, which closed on Sunday.Food safety has a bearing on people's health as well as the nation's sound and harmonious development, said Shi Xiushi, chairman of the Financial and Economic Committee of China's National People's Congress (NPC), at the opening, calling for efforts to raise companies' sense of responsibility and consumers' awareness in preventing and dealing with food safety crimes.The new campaign is part of a broader five-year program (2011-2015) of food safety education announced by the State Council Food Safety Commission (SCFSC) in May.The program aims for more than 80 percent of the public to be aware of basic food safety by 2015, with the rate for primary and high-school students reaching up to 85 percent or more.ARDUOUS WORKFood safety has become a growing public concern in China following a string of scandals over recent years. In the latest one, illegal workshops were found making and selling "gutter oil," which is processed from leftovers dredged from gutters.Gu Xiulian, former vice chairwoman of the NPC's Standing Committee, the country's top legislature, said ensuring safety is the top priority for the food sector, the country's pillar industry with an output of 550 million yuan (97.3 million U.S. dollars) in the first nine months of 2011.The development of the nation's food safety has failed to keep up with the demands of a public whose living standards have improved substantially in recent years, said Shi.Pledging to do everything it can to ensure food safety, the government takes a zero-tolerance approach to companies that sell unsafe food. In 2010 alone, authorities across the country investigated and handled 130,000 cases of food safety violations, shutting down more than 100,000 companies, according to the SCFSC."The food industry's overall development level is relatively low. There are weak links in the sector's credibility, management, detection techniques and even the laws and regulations," said Pu Changcheng, deputy director of the Administration of Quality Supervision, Inspection and Quarantine.Pu's points are exemplified by China's agricultural industry, which is largely based around small-scale production managed by disparate bodies. It would be a formidable task to eradicate the sector's safety issues.The catering business also faces a similar plight. The country has issued licenses to 2.2 million catering companies, most of which are small and individually operated, making safety supervision extremely difficult, according to Bian Zhenjia, deputy head of the State Food and Drug Administration.

WASHINGTON, Dec. 22 (Xinhua) -- The journal Science on Thursday chose the HPTN 052 clinical trial, an international HIV prevention trial as the 2011 Breakthrough of the Year.The study found that if HIV-infected heterosexual individuals begin taking anti-retroviral medicines when their immune systems are relatively healthy as opposed to delaying therapy until the disease has advanced, they are 96 percent less likely to transmit the virus to their uninfected partners. Findings from the trial, first announced in May, were published in the New England Journal of Medicine in August.The study was funded by the U.S. National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health."The HPTN 052 study convincingly demonstrated that anti- retroviral medications can not only treat but also prevent the transmission of HIV infection among heterosexual individuals," said NIAID Director Anthony Fauci in a statement. "We are pleased that Science recognized the extraordinary public health significance of these study results."Science's list of nine other ground-breaking scientific achievements from 2011 include:The Hayabusa Mission: After some near-disastrous technical difficulties and a stunningly successful recovery, Japan's Hayabusa spacecraft returned to Earth with dust from the surface of a large, S-type asteroid. This asteroid dust represented the first direct sampling of a planetary body in 35 years, and analysis of the grains confirmed that the most common meteorites found on Earth, known as ordinary chondrules, are born from these much larger, S-type asteroids.Unraveling Human Origins: Studying the genetic code of both ancient and modern human beings, researchers discovered that many humans still carry DNA variants inherited from archaic humans, such as the mysterious Denisovans in Asia and still-unidentified ancestors in Africa. One study this year revealed how archaic humans likely shaped our modern immune systems, and an analysis of Australopithecus sediba fossils in South Africa showed that the ancient hominin possessed both primitive and Homo-like traits.Capturing a Photosynthetic Protein: In vivid detail, researchers in Japan have mapped the structure of the Photosystem II, or PSII, protein that plants use to split water into hydrogen and oxygen atoms. The crystal-clear image shows off the protein's catalytic core and reveals the specific orientation of atoms within. Now, scientists have access to this catalytic structure that is essential for life on Earth -- one that may also hold the key to a powerful source of clean energy.Pristine Gas in Space: Astronomers using the Keck telescope in Hawaii to probe the faraway universe wound up discovering two clouds of hydrogen gas that seem to have maintained their original chemistry for two billion years after the big bang. Other researchers identified a star that is almost completely devoid of metals, just as the universe's earliest stars must have been, but that formed much later. The discoveries show that pockets of matter persisted unscathed amid eons of cosmic violence.
BEIJING, Nov. 9 (Xinhuanet) -- Kids with a depressed father tend to have more behavior issues than those with a happy father, a latest US study shows.The study, published in the journal Pediatrics, used data from home interviews with almost 22,000 families. All of them had a child aged between five and 17, and both a mother and father living at home, according to a Reuters report Tuesday.After analyzing the data, researchers found 11 percent of the children with a depressed father had problems at home or at school, whereas only six percent of those with a happy father had such problems.This is one of the first large-scale studies focusing on the connection between depressed fathers and children's behavior, said study author Michael Weitzman from the New York University School of Medicine.In addition, the study echoed the previous finding that mothers' depression could increase children's emotional and behavior problems.It was reported that 19 percent of the children in the study struggled emotionally and behaviorally if their mother was depressed."Parents who are depressed tend to engage less with their children, tend to display less positive behaviors, and display more harsh, negative and critical behaviors," said Jeremy Pettit, a psychologist not involved in the study, cited by Reuters.
SAN FRANCISCO, Nov. 9 (Xinhua) -- Cisco Systems Inc., the world 's biggest networking equipment maker, on Wednesday reported that its profit fell about 7.9 percent in the most recent quarter.In the company's fiscal 2012 first quarter ending on Oct. 29, Cisco posted its net income of nearly 1.78 billion U.S. dollars, compared with 1.93 billion dollars in the same period a year earlier.Excluding some items, earnings per share in the quarter were 43 cents, better than the 39 cents estimated by analysts, according to Bloomberg.Cisco's sales in the quarter reached 11.26 billion dollars, an increase of 4.7 percent year-on-year and also topped analysts' projection of about 11 billion dollars."We delivered a solid quarter," John Chambers, Cisco's chief executive officer, said in a statement."We've completed the majority of our restructuring and have organized Cisco to successfully execute against our strategy of providing intelligent networks, architectures and integrated products that solve customers' business problems," he added.
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