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WASHINGTON, Oct. 18 (Xinhua) -- Heart failure (HF) hospitalizations dropped 29.5 percent nationally over the past decade, according to a study by Yale physicians to be published Wednesday in the Journal of the American Medical Association.The risk-adjusted rate of heart failure hospitalization fell from 2,845 to 2,007 per 100,000 person-years from 1998 to 2008 in a fee-for-service Medicare claims analysis by Dr. Jersey Chen of Yale University and colleagues.The team also found that the rate of hospitalization for black men dropped at a lower rate, and that one-year mortality rates declined slightly during that period, but remained high.HF imposes one of the highest disease burdens of any medical condition in the United States and the risk increases with age. As a result, HF ranks as the most frequent cause of hospitalization and re-hospitalization among senior Americans. HF is also one of the most resource-intensive conditions, with direct and indirect costs in the United States estimated at 39.2 billion U.S. dollars in 2010.The study showed that the HF hospitalization rates varied significantly from state to state. The decline in the hospitalization rate from 1998 to 2008 was significantly higher than the national average in 16 states and significantly lower in three states (Wyoming, Rhode Island and Connecticut).Chen and his team also found that risk-adjusted one-year mortality decreased from 31.7 percent to 29.6 percent between 1999 and 2008, a relative decline of 6.6 percent, with substantial variation in different states."Because of the substantial decline in HF hospitalizations, compared to the rate of 1998, there were an estimated 229,000 fewer HF hospitalizations in 2008," said Chen in a statement, adding that with a mean HF hospitalization cost of 18,000 dollars in 2008, this decline represents a savings of 4.1 billion dollars in fee-for-service Medicare."The overall decline in the heart failure hospitalization rate was mainly due to fewer individual patients being hospitalized with heart failure rather than a reduction in the frequency of repeat hospitalizations," said Chen.
WASHINGTON, Dec. 7 (Xinhua) -- Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study published Wednesday in the Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.Aging-related memory loss is associated with the gradual deterioration of the structure and function of synapses (the connections between brain cells) in brain regions critical to learning and memory, such as the hippocampus.Recent studies suggested that histone acetylation, a chemical process that controls whether genes are turned on, affects this process. Specifically, it affects brain cells' ability to alter the strength and structure of their connections for information storage, a process known as synaptic plasticity, which is a cellular signature of memory.In the current study, Cui-Wei Xie, of the University of California, Los Angeles, and colleagues found that compared with younger rats, hippocampi from older rats have less brain-derived neurotrophic factor (BDNF) -- a protein that promotes synaptic plasticity -- and less histone acetylation of the Bdnf gene. By treating the hippocampal tissue from older animals with a drug that increased histone acetylation, they were able to restore BDNF production and synaptic plasticity to levels found in younger animals."These findings shed light on why synapses become less efficient and more vulnerable to impairment during aging," said Xie, who led the study. "Such knowledge could help develop new drugs for cognitive aging and aging-related neurodegenerative diseases, such as Alzheimer's disease," she added.

SAN FRANCISCO, Oct. 5 (Xinhua) -- Google announced Wednesday that Google Earth, the tech giant's virtual globe, map and geographical information program, has been downloaded more than one billion times since it was first introduced in 2005.According to Google's official blog, there have been more than one billion downloads of the Google Earth desktop client, mobile apps and the Google Earth plug-in. To celebrate the milestone, Google is aggregating all the interesting ways people have used Google Earth around the world and posting them on "www. OneWorldManyStories.com.""We never imagined our geospatial technology would be used by people in so many unexpected ways," said Google in the blog post.Google Earth maps the Earth by images obtained from satellite imagery, aerial photography and GIS (geographic information system) 3D globe. It also has versions of Moon, Mars and Sky, enabling users to see images and videos of the planets and distant galaxies.It is currently available in Google Earth, a free version with limited function, as well as Google Earth Pro and Google Earth Enterprise, subscription services with additional features intended for commercial use.
UNITED NATIONS, Nov. 18 (Xinhua) -- China on Friday voiced its hope that countries concerned "will continue to appropriately address the issue" of the alleged plot to kill Saudi Arabian ambassador to the United States "through dialogue and make joint efforts to maintain peace and stability in the Middle East and the Gulf region."The statement came as Li Baodong, Chinese permanent representative to the United Nations, was addressing the UN General Assembly to explain the Chinese position on the issue after he abstained from voting on the draft resolution on the alleged Iranian involvement in the assassination plot."China hopes countries concerned will continue to appropriately address the issue through dialogue and make joint efforts to maintain peace and stability in the Middle East and the Gulf region," he said."At present, the case is highly complicated and sensitive," Li said. "Parties still have different views over the issue. Any conclusion or action must be based on comprehensive, impartial, objective and transparent investigation and substantial evidence.""Before facts are out, parties should adopt a prudent approach, refrain from jumping to conclusions, and avoid action that may complicate and worsen the situation," he said."China abstained from the vote on the General Assembly draft resolution entitled 'Terrorist Attacks on Internationally Protected Persons'," he said. "We oppose all forms of terrorism, and always stand for compliance with international law and the basis norms governing international relations in handling state-to- state relations as well as effective protection of the safety and security of diplomatic personnel."Earlier on Friday, the UN General Assembly adopted a resolution which expressed deep concerns at the assassination plot and called on Iran "to comply with all of its obligations under international law." Iran strongly denied the allegation.Before or after the vote, countries such as Bolivia, Sudan and Venezuela said that due to a lack of solid evidence to support the allegation, the draft adoption would "create a dangerous precedent " in the international relations.
SAN FRANCISCO, Jan. 13 (Xinhua) -- Google seems to get no blessings for a good start for its New Year resolutions as the Internet search giant got an earful of complaints about its new social search service and felt mortified by a customer-poaching scandal in its Kenyan division.On Tuesday, Google announced "search plus your world" to deliver personalized search results by embedding its social service Google+ to its search engine.Although Google called it as "a beautiful journey begins," competitors and industry watchers said it was "a bad day for the Internet." They accused the company of using its dominant search engine to promote its own social networking site by giving Google+ pages and profiles an artificially prominent position in search results.The search giant first had a public bickering with Twitter which issued a statement on Tuesday saying that "As we've seen time and time again, news breaks first on Twitter. We're concerned that as a result of Google's changes, finding this information will be much harder for everyone."Google on Wednesday made a statement on its official Google+ page, saying that "We're a bit surprised by Twitter's comments because they chose not to renew their agreement with us last summer." The agreement, in which Twitter gave Google access to public tweets, expired last July and was not renewed.Twitter fired back by demonstrating the inefficiency of the new Google search feature. Twitter general counsel Alex Macgillivray tweeted a page of Google search results for the search term "@WWE" which did not include World Wrestling Entertainment's Twitter page, but Google+ page.Macgillivray noted that with 792,642 followers on Twitter compared with 24,900 followers on Google+, WWE's Twitter page is a more relevant social source than Google page and should be presented in Google's search results.Facebook, Google+'s major rival, has been remaining silent this week publicly while its employees criticized Google's moves in public status updates. Several prominent Facebook engineers and directors shared a tech blog about switching default search engine to Microsoft's Bing after "Google broke itself."Facebook has been working with Microsoft to allow Bing to reveal more personalized content.Industry watchers are also crying foul at the privacy and antitrust concerns raised by the new search feature. Search Engine Land, a tech blog closely following Google's news, posted several examples of how Google favors its own social networking service.Industry watchdog Electronic Privacy Information Center told the Los Angeles Times that the group is considering filing a complaint with the U.S. Federal Trade Commission (FTC). The organization once made the complaint that resulted in Google's settlement with the FTC last year that requires the Mountain View, California-based company to submit to external audits of their privacy practices every other year.On Friday, a Kenyan business directory startup Mocality said that Getting Kenyan Businesses Online, a Google-backed initiative to give small businesses free websites for one year, routinely accessed Mocality's database to obtain sales leads.The Search giant's Kenyan division called Mocality customers to pitch Google's alternative service, claiming they have had a partnership with Mocality. Mocality CEO Stefan Magdalinski said there is no such partnership.In a statement sent to the U.S. media, Google said it is " mortified" to learn that a team representing Google improperly used Mocality's data and misrepresented their relationship with the Kenyan company, noting that it "unreservedly apologized to Mocality" and is still investigating the issue.On Monday, BBC revealed that Google admitted profiting from advertisements of illegal websites selling drugs, fake passports and unauthorized tickets for the 2012 Olympics.The ads had been removed by Google after they were brought to the company's attention, but the search giant told BBC that the company "keeps any money it might make from companies advertising illegal services before such ads are removed."Meanwhile, on Thursday, Microsoft announced it has signed a patent licensing agreement with LG Electronics on the manufacturer 's devices running Google Android platform, leaving Motorola Mobility the only major Android-powered device maker that refuses to strike a deal with Microsoft.After the announcement, Microsoft's directors have been taking to Twitter to taunt Google as the two companies had a history of public back-and-forth. But so far, it appeared that Google didn't have time to needle back.
来源:资阳报