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As we're all focused on the current rollout of the COVID-19 vaccine, a technology known as thin-film freezing is getting a lot of attention. It's groundbreaking and could change the way we administer drugs or use medicine in general.You've probably heard about the need to keep the COVID-19 vaccine cold. It has to be so cold, in fact, that the shipment and transport are challenging. Well, what if that vaccine could be turned into powder?“What we’ve most recently been working on is the elimination of cold chain by storing as a powder, a dry powder where the drug is much more stable than if it was stored as a liquid or as a frozen liquid,” said co-inventor Dr. Robert Williams.Williams said it would eliminate the need for extreme cold storage and transport. The technology isn't new. He got a research grant and came up with it about 15 years ago.Williams, who is also a pharmacy professor at the University of Texas in Austin, said they were working on the technology and its multiple uses when the pandemic hit. And all of a sudden, they got a lot of attention.“We have published over 70 papers on the technology and using it for different products- it’s quite a mature process," Williams said. "We developed it because with other vaccines, the majority of the vaccine cost is in wastage because of this cold chain issue, so we published several key papers where we showed our thin-film freezing technology would protect vaccines - and you wouldn’t need cold chain storage.”Glenn Mattes, President, and CEO of TFF Pharmaceuticals added that the powders can be converted to topical preparations and they are currently working with the US Army to take some of the preparations and would then administer them directly through the eye.TFF is launching thin-film freezing into development through the FDA process. “I use the term ubiquitous because it is and disruptive because it is,” Mattes said. He added that they've explored their technology in the cannabinoid realm. But, as for the COVID vaccine, they're aiming for a second-generation usage.“To truly eradicate the pandemic, you have to have a global response," Mattes said. "The companies we’ve been speaking to certainly recognize the broad utilization of the technology but the application to the developing world, rural area, remote areas, where you can take a powder and inhale it or take the powder and reconstitute it has tremendous potential."Experts say it is only just the beginning as they launch their technology into a new world. 2511
ATLANTIC CITY, N.J. (AP) — The federal government is warning Americans to brace for a "floodier" future.Government scientists predict 40 places in the U.S. will experience higher than normal rates of so-called sunny day flooding this year because of rising sea levels and an abnormal El Nino weather system.A report released Wednesday by the National Oceanic and Atmospheric Administration predicts that sunny day flooding, also known as tidal flooding, will continue to increase."The future is already here, a floodier future," said William Sweet, a NOAA oceanographer and lead author of the study.RELATED: Devastating 'ARk' storm envisioned for California by U.S. Geological SurveyThe report predicted that annual flood records will be broken again next year and for years and decades to come from sea-level rise."Flooding that decades ago usually happened only during a powerful or localized storm can now happen when a steady breeze or a change in coastal current overlaps with a high tide," it read.The nationwide average frequency of sunny day flooding in 2018 was five days a year, tying a record set in 2015.But the East Coast averaged twice as much flooding.The agency says the level of sunny day flooding in the U.S. has doubled since 2000.Nationwide, the agency predicted, average sunny day flooding could reach 7 to 15 days a year by 2030, and 25 to 75 days a year by 2050.RELATED: How to check if your neighborhood is at risk of flooding"We cannot wait to act," said Nicole LeBoeuf, acting director of NOAA's Ocean Service. "This issue gets more urgent and complicated with every passing day."Global sea levels are rising at a rate of about 3 millimeters a year, or about an inch every eight years, according to Rutgers University researchers, who predict that by 2050, seas off New Jersey will rise by an additional 1.4 feet (0.4 meters).The study noted floods interfering with traffic in northeast states, swamping septic systems in Florida and choking Delaware and Maryland coastal farms with saltwater over the past year.Baltimore experienced 12 days of high-tide flooding from 1902 to 1936. Within the last 12 months, it experienced an additional 12 days.Robert Kopp, a leading climate scientist with Rutgers University, who was not involved in the study, said it confirmed many well-established trends."It's simple arithmetic: If you have higher sea level, you will have tides causing flooding," he said. "We're not talking about disaster flooding. We're talking about repetitive flooding that disrupts people's lives on a daily basis. It's sometimes called 'nuisance flooding,' but it has real impacts and costs."RELATED: Mega storm could cause billions in damage to California, report showsThe report cited the disruption of commerce in downtown Annapolis, Maryland, where parking spaces are lost to flooding. A 2017 study put the price tag on lost economic activity at as much as 2,000. The water table has risen to ground level and degraded septic systems in the Miami region, and farmlands in the Delmarva Peninsula in Delaware and Maryland have been damaged by salt water encroaching into planted areas.High-tide flooding is causing problems including beach erosion, overwhelmed sewer and drinking water systems, closed roadways, disrupted harbor operations, degraded infrastructure and reduced property values — problems which "are nearly certain to get much worse this century," the report read.The report's statistics cover May 2018 through April 2019.The agency forecasts sunny-day flooding this year in Boston at 12 to 19 days (it had 19 last year). It predicted sunny-day flooding this year in New York (8 to 13 days, compared with 12 last year); Norfolk, Virginia (10 to 15 days; compared to 10 days last year); Charleston, South Carolina (4 to 7 days, compared to 5 last year); Pensacola, Florida (2 to 5 days compared with 4 last year); Sabine Pass, Texas (6 to 13 days compared with 8 last year) and Eagle Point, Texas (29 to 40 days, compared to 27 last year).West coast predictions included San Diego (5 to 9 days compared to 8 last year); Los Angeles (1 to 4 days compared to 5 last year); Humboldt Bay, California (6 to 12 days compared to 12 last year); Toke Point, Washington (9 to 21 days compared to 12 last year) and 2 to 6 days in Seattle, compared to 2 last year.The report documented that 12 locations broke or ties their record of sunny day flooding last year, including 22 in Washington, D.C., 14 in Wilmington, North Carolina; and 12 each in Baltimore and Annapolis.FEMA created flood maps of San Diego County which enable users to search by their address. Click here to find your hazard risk. 4654
As you might have heard I teamed up with @PattyJenks and @LKalogridis to bring the story of Cleopatra, Queen of Egypt, to the big screen in a way she’s never been seen before. To tell her story for the first time through women's eyes, both behind and in front of the camera. pic.twitter.com/k5eyTIfzjB— Gal Gadot (@GalGadot) October 12, 2020 349
ATLANTA (AP) — A former Navy SEAL who claims to have killed Osama bin Laden has been banned by Delta Air Lines after removing his face mask during a flight.Robert O'Neill tweeted about his ban on Thursday, and the airline confirmed its action.I just got banned from @Delta for posting a picture. Wow.— Robert J. O'Neill (@mchooyah) August 20, 2020 O'Neill posted and later deleted a selfie showing himself with no mask on a plane.The incident happened Wednesday on flight from Minneapolis to Newark, New Jersey.All major U.S. airlines require passengers to wear face coverings to prevent the spread of COVID-19.Delta says it has banned more than 100 passengers for violating the rule. 692
At least 71 people were killed and 325 others wounded in rebel-held Eastern Ghouta after the Syrian government carried out a series of airstrikes and artillery bombardments, the UK-based Syrian Observatory for Human Rights said Monday.Sixty-two of the victims were civilians, including nine children and five women. Nine militants were killed, the group said of the attacks near Damascus over a 24-hour period.CNN could not independently verify the claim.The Eastern Ghouta area has been surrounded by Syrian forces for more than four years, with the siege intensifying last May when government forces conducted a large-scale offensive.It was supposed to be one of the "de-escalation zones," according to the peace agreement struck by Russia, Turkey and Iran in May 2017.About 400,000 Syrians have been killed since the conflict erupted in 2011, according to the United Nations. As many as 5.4 million Syrians have left their country, the UN Refugee Agency said, and 6.1 million are displaced from their homes but still inside Syria. The UNHCR High Commissioner, Filippo Grandi, calls the situation in Syria "the biggest humanitarian and refugee crisis of our time."The-CNN-Wire? & ? 2018 Cable News Network, Inc., a Time Warner Company. All rights reserved. 1270