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LOS ANGELES (CNS) - USC researchers have found the likely order in which COVID-19 symptoms first appear: fever, then cough and muscle pain, followed by nausea, and/or vomiting, and diarrhea, it was announced Thursday.Knowing the order of COVID-19's symptoms may help patients seek care promptly or decide sooner than later to self isolate, according to scientists at the USC Michelson Center for Convergent Bioscience. The information also may help doctors rule out other illnesses, or help doctors plan how to treat patients, and perhaps intervene earlier in the disease.The study, which appears in the journal Frontiers in Public Health, was led by doctoral candidate Joseph Larsen and scientists Peter Kuhn and James Hicks at the USC Michelson Center's Convergent Science Institute in Cancer."This order is especially important to know when we have overlapping cycles of illnesses like the flu that coincide with infections of COVID-19," said Kuhn, a USC professor of medicine, biomedical engineering, and aerospace and mechanical engineering. "Doctors can determine what steps to take to care for the patient, and they may prevent the patient's condition from worsening."Fever and cough are frequently associated with a variety of respiratory illnesses, including influenza, Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome. But the timing and symptoms in the upper and lower gastrointestinal tract set COVID-19 apart."Given that there are now better approaches to treatments for COVID- 19, identifying patients earlier could reduce hospitalization time," Larsen said.To determine COVID symptom chronology, the authors analyzed more than 55,000 confirmed coronavirus cases in China collected from Feb. 16 to Feb. 24 by the World Health Organization. They also studied a dataset of nearly 1,100 cases collected from Dec. 11 through Jan. 29 by the China Medical Treatment Expert Group via the National Health Commission of China.In addition, to compare the order of COVID-19 symptoms to influenza, the researchers examined data from 2,470 cases in North America, Europe and the Southern Hemisphere, which were reported to health authorities from 1994 to 1998."The order of the symptoms matter, " Larsen said. "Knowing that each illness progresses differently means that doctors can identify sooner whether someone likely has COVID-19, or another illness, which can help them make better treatment decisions." 2440
LIVE COVERAGE:SAN DIEGO (KGTV) — Hundreds of protesters gathered outside the San Diego Hall of Justice Sunday afternoon, demonstrating against police brutality.Protesters in San Diego called for justice for George Floyd, whose in-custody death in Minneapolis has sparked protests around the nation. See updates on Sunday's protests below (refresh for updates):UPDATE 12:30 a.m. Monday - Mayor Kevin Faulconer tweets, "Peaceful protesters march because they care about our community, justice, and accountability. Looters and rioters do not. We won’t stand for anyone hijacking this moment to perpetuate violence. The City will keep working to maintain order."------UPDATE 12:25 a.m. Monday - Police say rocks are being thrown at officers at 500 Broadway and that more arrests are being made.------UPDATE 11:42 p.m. - San Diego Police officers reporting on Twitter they are taking rocks at State St. and Broadway with damage. Vandalism with bats to businesses at Kettner and West Broadway are being reported as well.-------UPDATE 11:32 p.m. - SDPD are arresting a handful of people at 4th Ave. and Beech St. At least 10 people have been placed in handcuffs, according to reporter Adam Racusin.------UPDATE 10:31 p.m. - San Diego Police say they are continuing to respond to vandalism and rock throwing at officer downtown near C and State streets.------UPDATE 10:03 p.m. - San Diego Police report on Twitter that vehicles near Union and A St. are being attacked with rocks. SDPD adds that the demonstration at Pacific Highway and Broadway has been declared an unlawful assembly due to "violence and vandalism" and are telling people to leave. ------UPDATE 9:28 p.m. - San Diego Police officers arrive at Fourth Ave. and C St. Windows are broken at the CVS Pharmacy, according to 10News reporter Adam Racusin. Windows have been broken at an empty building at 5th and C Streets as well.------UPDATE 9:02 p.m. - San Diego deputies continue to try and force protesters to leave the County Administration Building using tear gas. Many have left, but some are still at the scene, 10News reporter Adam Racusin reports.------UPDATE 8:38 p.m. - SDSO has reportedly started to fire tear gas at the County Administration Building. 10News reporter Adam Racusin reports he is hearing pepper balls used as well.------UPDATE 8:23 p.m. - San Diego Sheriffs Department has declared the protest outside County Administration Building an unlawful assembly. SDSO telling people if they do not leave, they will be arrested. Some in the crowd have left, others are staying. ------ UPDATE 7:41 p.m. - Protesters continue to demonstrate on the steps of the County Administration Building, with several people addressing the crowd. ------UPDATE 6:39 p.m. - Protesters gathered at the County Administration Building near Waterfront Park to hold 8 minutes of silence for George Floyd.------UPDATE 4:01 p.m. - SDPD officers continue to push back protesters using tear gas near First St. and Broadway.------UPDATE 3:27 p.m. - San Diego Police have deployed tear gas at First St. and Broadway in addition to giving dispersal orders, SDPD tweeted.------UPDATE 3:17 p.m. - SDPD is now making unlawful assembly announcements downtown and asking protesters to disperse "due to the escalation of violence by the protesters," police tweeted. ------UPDATE 3:07 p.m. - San Diego Police officers have arrested at least one person downtown, as officers are using crowd-dispersal techniques.------UPDATE 3:05 p.m. - Fashion Valley Mall is closed due to potential protesters. Other restaurants in the area are reportedly closing as well.------UPDATE 3:03 p.m. - Caltrans has updated traffic closures to include the following: NB/SB I-5 (mainline), SB SR-163 transition to SB I-5SB I-5 transition to EB SR-94C St, E St and Imperial on-ramps to SB I-5 have all reopened to trafficThe San Diego-Coronado Bay Bridge remains closed in both directions due to police activity------UPDATE 2:50 p.m. - SDPD says officers are taking rocks and bottles at Front St. and Broadway and that multiple police vehicles have been vandalized.------UPDATE 2:39 p.m. - San Diego Police are reporting an "aggressive crowd" at State St. and Broadway and people throwing objects at officers.------UPDATE 2:18 p.m. - San Diego Police say about 100-200 protesters were reportedly throwing rocks and bottles at officers at 300 Broadway. No force was used and rocks and bottles have since stopped. Numerous groups are walking in different areas of downtown and motorists are advised to be careful and stay clear if possible, SDPD added.------UPDATE 1:34 p.m. - Caltrans says the following closures are in place due to police activity: NB/SB I-5 from SR-163 to Cesar Chavez PkwySan Diego-Coronado Bay Bridge (in both directions)SB SR-163 transition to SB I-5SB I-5 transition to EB SR-94C St, E St and Imperial on-ramps to SB I-5.See updated traffic map here.------UPDATE 1:31 p.m. - La Mesa will have another citywide curfew Sunday from 7 p.m. to 7 a.m. on Monday, according to La Mesa councilmember Akilah Weber.------UPDATE 1:29 p.m. - San Diego Police say a group of protesters has moved onto I-5 near B St. and remain peaceful. SDPD is asking motorists to be aware of closures in the area. Inbound and outbound traffic has been closed on the Coronado bridge, according to the City of Coronado.------UPDATE 1:22 p.m. - San Diego Police say they are asking protesters outside their headquarters to move to a larger area at the intersection of 15 and E streets to continue demonstrating. Police say the protest has remained peaceful. 5569

LOS ANGELES (KGTV) -- According to multiple media reports and NBA insiders, one of the summer's most coveted free agents Kawhi Leonard will be joining the Los Angeles Clippers.Friday's news ends days of KawhiWatch, a media and fan frenzy that included a helicopter chase and people camping outside hotels hoping to persuade the 2019 NBA Finals MVP to stay with the Toronto Raptors, or join either the Los Angeles Lakers or Clippers.Leonard's camp has not released an official announcement nor made any comments on the reports as of Friday night.The former San Diego State University star will be joining a young and exciting Clippers team that won two games against the top-seeded Golden State Warriors in the first round of this year's Western Conference playoffs. The Leonard signing now makes the Clippers a top contender for the 2019-2020 NBA title.The Lakers were the heavy favorites in the Kawhi Sweepstakes. The Lakers dealt away a youthful core of assets to the New Orleans Pelicans for power forward All-Star Anthony Davis in hopes of landing the league's baller trifecta of LeBron James, Davis, and Leonard -- AKA the Big 3.Leonard, a 6'7" small forward who grew up in Los Angeles and played at SDSU for two seasons, will join All-Star forward Paul George, who was reportedly acquired via a trade with Oklahoma City, also on Friday night.The 28-year-old Leonard is expected to sign a four-year, 2 million maximum contract, according to ESPN Senior NBA insider Adrian Wojnarowski.A Friday night @wojespn bomb this lifelong @LAClippers fan never thought he'd see! Kawhi and Paul George. Is it #NBA season yet?— Jeff Lasky (@10NewsLasky) July 6, 2019GEORGE TO CLIPSWojnarowski reports that the "Clippers are sending the Thunder four unprotected first-round picks, one protected first-round pick and two pick swaps, league sources tell ESPN. Those picks go to OKC with Gallinari and SGA." 1907
LOS ANGELES (AP) — The latest on the midterm election in California.11:40 p.m.California's appointed Democratic Attorney General Xavier Becerra has won election after promising voters he will keep fighting Trump administration policies. 244
LONDON (AP) — Angelina Jolie has not ruled out a move into politics — and has joked that she might be tough enough to take the rough and tumble that comes with it.The American actress and U.N. envoy told BBC radio she "can take a lot on the chin" — a possible reference to her bitter divorce from Brad Pitt.When asked if she is moving in the direction of politics, the 43-year-old Oscar winner said, "I honestly will do whatever I think can really make change."Jolie is a special envoy for the U.N. refugee agency. She used her slot as a "guest editor" on the BBC to highlight refugee issues in the Middle East.She also included Chinese artist Ai Weiwei and Nobel Peace Prize winner Denis Mukwege on the show. 717
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