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SAN DIEGO (KGTV) - Businesses are bracing for Governor Gavin Newsom's announcement Monday after San Diego has been on the state's watch-list since July 3, due to a surge in coronavirus cases.Newsom could announce indoor activities, like arcades, restaurant dining, movie theaters and museums will be shut down to contain the spread.This news comes as San Diego restaurants faced a volley of changes over the past four months."I think that the only thing that is constant is the change," Chief Brewing Officer Mike Hess said from his Imperial Beach brewery.He said the lucky thing about most of his locations is they have outdoor space, so they can shift more easily. "I called everybody Friday when we got word when it might change on Monday and everybody was like ‘Okay what do we need to do?’" He said sighing.READ RELATED: Mike Hess Brewing Company serving up a different type of alcoholSome of the changes he's made to be compliant with health orders have come at quite a cost. He said in one pay period his labor costs at the Imperial Beach location are three times the norm because they switched from bar service to table service and have to sanitize more often.Across town at Small Bar, Owner Karen Barnett said they shut down at the beginning of July and don't have any plans to reopen.'At the end of the day a business is a business, people are more important.' Barnett said they have been doing take out since the beginning of the pandemic, but never reopened for dine in.She said the small space at her business and horror stories of other restaurants and bars dealing with enforcing social distancing, wearing a mask and employees testing positive with the virus, helped her stick to her guns.On Friday, she posted this on Instagram, "After much consideration, Small Bar will be closing for the entire month of July (possibly longer). When the global pandemic was declared almost 4 months ago, we decided to quickly switch gears and continue to serve our community as thoughtfully and safely as possible. Unfortunately, Americans both near and far don't seem to be listening as closely to science as we are. We no longer deem our services "essential". We care about our community and feel the best move right now is to take a step back for a few weeks. In the meantime, we will be working on our footprint and how we can safely reopen later. We encourage more businesses to follow our lead to help flatten the curve, yet again. We will be working on ways to serve with as little contact as possible, but until that time we wish you all health and peace in the world. Take care."Monday we will find out if all restaurants will have to shut down inside dining, and wait at least three weeks until reopening. 2725

SAN DIEGO (KGTV) -- Baseball is back, and that could mean potentially good news for businesses near Petco Park in downtown San Diego.On Tuesday, Major League Baseball announced a 60-game season will begin on July 23 and 24. Players are expected to return for training camps on July 1.While the MLB announcement did not specify the role of fans, multiple reports suggest the season will begin in empty ballparks with no fans in attendance.To reduce travel, the schedule will include 10 games for each team against its divisional opponents, along with 20 games against the opposite leagues corresponding geographical division.For the San Diego Padres, that will mean 10 games each against the San Francisco Giants, Los Angeles Dodgers, Arizona Diamondbacks, and Colorado Rockies. The Padres will also play teams from the American League West."Major League Baseball is thrilled to announce that the 2020 season is on the horizon," MLB Commissioner Robert Manfred said in a news release. "We have provided the Players Association with a schedule to play 60 games and are excited to provide our great fans with Baseball again.Businesses near Petco Park welcomed the news.Brant Crenshaw, co-owner of the sports bar Social Tap, which is located next to the ballpark, said the pandemic has hurt business. He is hopeful that the return of baseball will lead the way for more sports to return. He said it could help bring some customers back, especially if fans aren't yet allowed back into the ballparks."The only way you're going to be able to watch these games is on TV, and you can come down here and watch every game," Crenshaw said. "It's a one-stop-shop, so if you're a fan of teams out of state, we'll have them playing. So, I think it will help to get some sports back on TV.” 1783

SAN DIEGO (KGTV) — As the world waits for a vaccine against the coronavirus, two San Diego biotechs are teaming up to develop a nasal spray using designer antibodies cloned from COVID-19 survivors.About 70 companies worldwide are working on therapies for COVID-19 using cloned antibodies, according to an estimate by the International AIDS Vaccine Initiative. A few of these treatments, known officially as monoclonal antibody therapies, have advanced to clinical trials.Most require an injection, but San Diego-based Diomics and its partner Active Motif, based in Carlsbad, are developing a once-a-day spray that could be easily self-administered.Early research suggests the coronavirus primarily enters the body through the nose. The spray, called Dioguard, is designed to coat the lining of the nasal cavity with cloned antibodies that are held in place for 24 hours or more using a proprietary polymer material developed by Diomics.Diomics CEO Anthony Zolezzi said he believes the spray “holds the key to allowing many aspects of life to resume until the day comes when there’s an effective vaccine in widespread use.”Diomics is also developing two tests for COVID-19 antibodies using its polymer beads, including a device that looks like a nicotine patch that is designed to monitor for infections for a week or more.RELATED: How a dot on your forearm could be the future sign of COVID immunityActive Motif is providing the cloned antibodies for the nasal spray. With a lab in Shanghai and other relationships in China, the Carlsbad company was able to clone antibodies from 11 Chinese survivors in February, before the World Health Organization declared a pandemic.When the company started the cloning project, they thought the virus would probably disappear in three to six months, said Active Motif CEO Ted DeFrank. “Then people started realizing, no this is going to be with us for a while.”The plasma from the 11 Chinese patients contained thousands of antibodies, and scientists with Active Motif set about selecting the one that was most effective, dubbed 414-1. The company says it can neutralize SARS-CoV-2 virus particles with 98 percent effectiveness.Monoclonal antibodies have some similarities to convalescent plasma, which is a complex cocktail of antibodies and other immune molecules drawn from the blood of recovered patients. One of the key differences is that cloned antibodies can be mass produced in a lab.Cloned antibodies have been used in treatments for more than 30 years, primarily for cancer. One such treatment famously helped former U.S. President Jimmy Carter beat melanoma.But of the more than 100 monoclonal antibody therapies licensed for use, only seven are for communicable diseases, according to IAVI.Historically, the treatments have been expensive and difficult to produce, but Diomics said it’s targeting a price of about a spray for Dioguard, roughly per bottle.“We do not want to have huge profits from a pandemic, that’s just wrong,” Zolezzi said. “We’re going to price this as effectively as we can for the masses. We want to get this out to the masses.”Animal testing is about to begin and the companies said they hope to progress to human trials soon. Their goal is to release the spray in early 2021, when a vaccine may be on the market but not yet widely available.If the spray works, it could be adapted to other viruses to help fight future pandemics, Zolezzi said."That’s our real goal," Zolezzi said. "That we never get caught flat-footed like this time." 3526

SAN DIEGO (KGTV) -- Caltrans is warning drivers about a series of SR-163 closures throughout the week. According to the agency, all lanes of north and southbound SR-163 between I-8 and Genesee Avenue for three to six nights. The highway will be closed so crews can remove falsework from the bridge on the SR-163 Friars Road overcrossing. The southbound closures will begin at 11 p.m. with the northbound closures starting at 11:30 p.m. All lanes will reopen at 5 a.m. The list below shows which lanes will be closed on certain nights: Sunday: All southbound lanes, the northbound far right collector lane and the right main lane (slow lane).Monday: No full freeway closure. Only the northbound and southbound right main lanes.Tuesday: All southbound lanes, and the northbound left lane (fast lane).Wednesday: All northbound lanes, and the southbound left lane.Thursday: No full freeway closures. Only the northbound right lane.Friday/Saturday: No freeway work scheduledSunday, March 10: All northbound lanes. During the closures, drivers on the northbound SR-163 will be rerouted to eastbound I-8 to northbound I-805 to the merge at northbound SR-163.Southbound motorists will be rerouted to southbound I-805 to westbound I-8 to the southbound SR-163 connector ramp. 1274

SAN DIEGO (KGTV) -- Class-action lawsuits have been filed all over the country over the Equifax data breach, affecting approximately 143 million consumers.RELATED: Massive Data Breach At Equifax Leaves 143M At RiskAt least two lawsuits have been filed in San Diego.Timothy Blood of Blood Hurst & O’Reardon represents a San Diego man who believes his information was stolen.“It really ends up affecting probably most households in the United States,” Blood said. “Equifax has been very aggressive, in my opinion, not dealing with this very well.”Blood believes the offer of one-year credit monitoring is not enough.“With something like a social security number, you have that for the rest of your life, so you will need protection for the rest of your life,” Blood said.RELATED:  800

来源：资阳报