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TIJUANA, Mexico (AP) — The asylum claims of six Hondurans were accepted for processing Tuesday, ending a 17-hour standoff involving U.S. authorities, the migrants and two U.S. lawmakers supporting them on a tiny piece of American soil at the country's border with Mexico.The Hondurans had camped out in an area of San Diego's Otay Mesa border crossing past where pedestrians pass a wall plaque delineating the international boundary but before they reach inspectors. They were joined by U.S. Reps. Nanette Barragan and Jimmy Gomez, both California Democrats."They're on U.S. soil, and they're basically being blocked for presenting themselves for asylum," Barragan said in a video posted on Twitter that she said was taken around 2:40 a.m.The asylum seekers arrived at the crossing Monday afternoon, and after several hours U.S. inspectors agreed to process claims of eight unaccompanied children and a mother and her five children, attorneys said. Six more were initially not allowed into the country and sat on blankets throughout a chilly night before authorities agreed Tuesday to process their claims."Children are sick, they're crying, they've had to use the bathroom," Nicole Ramos, an attorney at Al Otro Lado, a legal services organization working on behalf of the migrants, said Monday night. "We've had to get blankets and food for them."Customs and Border Protection did not comment on the status of the Honduran asylum seekers, but officials said claims are processed as quickly as possible.The impasse highlighted a U.S. practice to limit entry for asylum seekers at official crossings when they are at full capacity, which it calls "metering" or "queue management." Authorities emphatically deny they are turning away asylum seekers — something that is prohibited under U.S. and international law — and say they are simply asking them to temporarily wait in Mexico.CBP says a surge in asylum claims has strained resources. The number of people expressing fear of returning to their home countries — the initial step toward asylum — jumped 67 percent at Mexico border in the fiscal year that ended Sept. 30, rising to 92,959 claims from 55,584 the previous year.Critics contend that CBP is limiting the number of asylum claims to deter people from coming.In San Diego, U.S. authorities funnel asylum claims through the San Ysidro port of entry, the nation's busiest crossing. Asylum seekers themselves manage waiting lists in a tattered notebook on the Tijuana side.The wait at San Ysidro had neared 3,000 names even before a caravan of more than 6,000 people reached the border city last month. Typically 60 to 100 asylum claims are processed per day at the crossing, meaning many migrants will likely have to wait in Tijuana for months.People who appear at the city's other crossing, Otay Mesa, are normally redirected to San Ysidro. But Monday's group managed to reach U.S. soil, which usually means they are transferred to San Ysidro to have their claims processed immediately. 3003

There were 10 people shot and killed in Friday's shooting at Santa Fe High School in Texas. At least 10 others were wounded.So far, two victims have been publicly identified: a substitute teacher and an exchange student from Pakistan.Houston Texans defensive end JJ Watt has offered to pay for the funerals of the victims, according to a Houston Texans spokeswoman.Here's what we know about those who died:Cynthia TisdaleCynthia Tisdale was a substitute teacher at Santa Fe High School, her family told CNN. Her niece, Leia Olinde, said the family was notified of her death Friday night.Tisdale's brother-in-law, John Tisdale, said in a Facebook post Friday night that she was a member of the Anchor Bible Baptist Church in Pharr, Texas.John Tisdale also said in his post that his sister-in-law's husband, William Recie Tisdale, is "in bad health with a terminal lung disease." The couple has four children.Cynthia Tisdale's son, Recie Tisdale, told The Washington Post that his mother loved children and teaching."She started substitute teaching because she loved to help children," he told the newspaper. "She didn't have to do it. She did it because she loved it."Recie Tisdale is a police detective in League City, which is 10 miles away from Santa Fe, where the shooting took place.Sabika SheikhThe Embassy of Pakistan in Washington confirmed on Facebook that Sabika Sheikh, an exchange student, was killed in Friday's shooting."Ms. Sheikh was in Texas as part of the Youth Exchange & Study (YES) Programme," the embassy said in a statement to CNN. "Our thoughts and prayers are with Sabika's family and friends. Ambassador Aizaz Chaudhry spoke to the father of Sabika Sheikh expressing heartfelt condolences over the tragic death of his daughter."Abdul Aziz, Sabika's father, told AFP in Pakistan that he learned of his 17-year-old daughter's death on CNN."We are still in a state of denial," he said. "It is like a nightmare. ...There is a general impression that the life is safe and secure in America. But this is not the case."US Secretary of State Mike Pompeo said Sabika was "helping to build ties" between the US and her native country and offered his condolences to her family and friends."Sabika's death and that of the other victims is heartbreaking and will be mourned deeply both here in the United States, and in Pakistan," Pompeo said in a statement.US Ambassador to Pakistan David Hale tweeted a statement on Sheikh's death."This morning, I called the family of Sabika Sheikh and offered my deepest condolences. As an exchange student, Sabika was a youth ambassador, a bridge between our people and cultures. All of us at the U.S. Mission in Pakistan are devastated by and mourn her loss. We will honor her memory."The-CNN-Wire 2760

Too few new antibiotics are under development to combat the threat of multidrug-resistant infections, according to a new World Health Organization report published Tuesday. Adding to the concern: It is likely that the speed of increasing resistance will outpace the slow drug development process.As of May, a total of 51 antibiotics and 11 biologicals -- medical products often made from natural sources -- are being developed, the new report said."The idea is that biologicals could replace use of antibiotics, which could help in overcoming the resistance problem," Peter Beyer, an author of the report and senior adviser to the WHO's Department of Essential Medicines and Health Products, wrote in an email.Seemingly, this large number of potential new drugs should suffice, yet it is not nearly enough.First, just 33 of the antibiotics in the pipeline target priority pathogens. This year, the WHO published a list of a dozen "priority pathogens": 12 separate families of antibiotic-resistant bacteria that pose the greatest threat to human health.Among the priority pathogens is a drug-resistant tuberculosis, which kills about 250,000 people around the world each year, and a variety of multidrug resistant strains -- Acinetobacter, Pseudomonas and various Enterobacteriaceae -- which are responsible for infections in hospitals and nursing homes and among patients whose care requires ventilators and catheters.Of the 33 potential medicines for treating priority bug infections, only eight are innovative treatments. The other 25 are simple modifications of existing families of antibiotics. At best, then, the 25 will serve as short-term solutions since it is expected bacteria will quickly adapt to and resist these new (though somewhat familiar) drugs, according to the WHO."It is difficult to speculate why companies develop specific new medicines," Beyer noted. "But in general many new treatments do not necessarily constitute advances over existing treatments."TB infections require a combination of at least three antibiotics, according to the new report, yet only seven of the new TB medicines are even in clinical trials. Soon, there will be a serious lack of treatment options for this infection, the report warns.The same is true for gram-negative pathogens, which can cause severe, often deadly infections typically in hospitals and nursing homes.Gram-negative bacteria have more complex cell walls than gram-positive, explained Beyer. "In a nutshell, it is more complex to develop a novel antibiotic that can penetrate the complex gram-negative cell wall and stay inside the bacterium," he wrote.Finally, the WHO sees too few oral antibiotics being developed. These are necessary "to target the critical priority pathogens (and) be accessible in low- and middle-income countries," Beyer noted.To address the problem of developing new antibiotics, the WHO and the Drugs for Neglected Diseases Initiative set up the Global Antibiotic Research and Development Partnership. However, new drugs alone cannot combat the threat of antimicrobial resistance. The WHO is also working to improve infection prevention and control while developing guidance for the responsible use of antibiotics."Always seek medical advice before taking antibiotics and then always follow the advice of the health-care professional," Beyer noted.The new report is a "fantastic (and very useful!) summary" of the antibiotic situation, wrote Bill Hanage, an associate professor of epidemiology at Harvard T.H. Chan School of Public Health, in an email. Hanage, who has also published studies of antibiotic resistance, was not involved in the new report.Although the risk of getting a completely resistant infection is low in the United States, about 2 million people each year become infected with "resistant enough" bacteria that are harder to treat, Hanage said. And every year, more than 20,000 people die of these infections."More resistant infections don't just mean you or someone you care about is more likely to die from one, they also mean healthcare will get even more expensive," Hanage said. "Many of the procedures we take for granted in medicine, from cancer treatments to surgeries, depend on our ability to handle infections that happen in the course of treatment."The number of new drugs in development is simply not enough, he said."The great majority will not make it into the hands of doctors or your treatment," Hanage wrote. "As the report states, for drugs to be used in humans they have to pass 3 hurdles, the phase 1, 2 and 3 trials. Drugs entering that pipeline have just a 14% chance of getting all the way through to be used in humans." 4676

Three UCLA basketball players accused of shoplifting in China last week returned to Los Angeles on Tuesday.Video showed the three freshmen greeted by a media scrum as they walked out of a Los Angeles International Airport terminal about 6 p.m. (9 p.m. ET).US President Donald Trump earlier said he asked his Chinese counterpart to help in the case. 356

This illustration provided by Alex Boersma in July 2020 depicts a Kongonaphon kely, a tiny relative of dinosaurs and pterosaurs. Kongonaphon lived roughly 237 million years ago and would have stood only 10 centimeters (4 inches) tall. (Alex Boersma via AP) 264