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SAN DIEGO, Calif. – What’s usually a marathon for biotech companies is now a full-blown sprint to stop the spread of coronavirus.Kate Broderick, the Senior Vice President of R&D at Inovio Pharmaceuticals in San Diego, remembers the moment she first learned about the mysterious outbreak unfolding thousands of miles away. “Yes, absolutely, distinctly, probably one of those moments you’ll remember forever. I was in my kitchen at home the 31st of December,” said Broderick.She never imagined that two months later it would be the crisis it is today. “Every week I keep thinking it’s going to get better, it’s going to start to tone down a little bit, but in fact, rather than getting better it’s getting worse every week,” said Broderick.Inovio has made headlines before, creating vaccines for Zika, Ebola, and now the coronavirus. After Chinese researchers shared the genetic sequence of COVID-19, Inovio designed a vaccine in just three hours Using its proprietary DNA medicines platform technology. The vaccine was designed to precisely match the DNA sequence of the virus“In an outbreak setting we really don’t have two to three years to wait for a vaccine, so that’s where we come in at Inovio pharmaceuticals, we use DNA medicine technology,” said Broderick.While traditional vaccines use the virus itself, this method puts DNA inside E.coli, which naturally replicates the medicine over and over. The paste is then purified, leaving behind only the DNA medicine, which Inovio hopes to test in humans next month.“Infectious diseases are global and they don’t care about boundaries and borders, everyone is affected from childhood all the way through seniors,” said Phyllis Arthur, who’s been in the infectious disease industry for 20 years.Arthur is Vice President of Infectious Diseases and Diagnostic Policy at BIO, an association made up of about 1,000 companies.“One of the things we’re seeing, from outbreak to outbreak, unfortunately, is we’re getting faster at using platform technologies to build something that can be tried in humans sooner than we were the last time,” said Arthur.She’s following dozens of companies working on vaccines, treatments, and diagnostic tools. If their vaccines work, companies like Inovio will have to figure out how to manufacture them fast.“You may have the best vaccine in the world, but if you can only produce 1,000 doses of it, that’s not really going to help 1.4 billion people in China,” said Broderick. Continued funding will also be critical. Broderick says while their Zika vaccine looked promising in humans, it never ultimately got FDA approval for broad public use.“The problem there was, although great for global health, was that of course cases of the virus really steadily declined, the problem for us there was so did the funding,” said Broderick.She says that way of thinking is shortsighted but does see change on the horizon. “It’s a huge amount of responsibility on everyone’s shoulders, and I think we feel genuinely compelled to do everything in our power, hence why no one complains about two hours of sleep, because this is a point in our careers we can truly, literally, make a difference in saving lives, right now,” said Broderick.After the company begins human trials in the U.S., they’ll continue testing in China and South Korea. They hope to deliver one million doses by the end of the year.If they make it that far, it too would be a day Broderick will never forget. 3462

Super Blood Wolf Moon Eclipse. No, it's not a death metal band — it's a rare lunar phenomenon that will occur on Jan. 20.The super blood wolf moon eclipse is actually just the concurrence of three separate phenomena — a lunar eclipse, a super moon and a wolf moon. A lunar eclipse occurs when the Earth is positioned between the sun and the moon, casting the moon completely in the Earth's shadow and giving it an organish, "bloody" look. Full lunar eclipses occur between two and four times a year.A supermoon occurs when the moon is within 90 percent of its closest possible distance to the Earth. According to 625

Spaces usually filled with tens, hundreds, thousands of people -- are now empty."We're trying to navigate how to survive through this," Imam Muhammad Kolila said."You forget how much you value like giving someone a hug or shaking someone's hand," Christ-follower Claire Fundingsland said."Time right now is so bizarre. A day seems like a year," Senior Rabbi Joseph Black said.For many Americans, spiritual practice can offer a sense of peace. However, with shelter-in-place mandates across the country, the routine of gathering in person with a faith community is disrupted. Rabbis, Imams, and Pastors have all made changes to the way they usually worship."In one of our campuses, we'll put 4,000 people in one room, and that just didn't seem like the wisest idea," Lead Pastor Jim Burgen sad.Jim Burgen is the lead pastor of Flatirons Community Church. It's one of the largest churches in the U.S., fitting 16 to 18 thousand people into its five campuses each week. The church already had an online presence, so moving to virtual services was a relatively smooth transition. However, the pastor says preaching to an empty building seemed a bit inauthentic."Now we're using this opportunity to do something different," Burgen said. "I just recorded my sermon for this weekend in an empty coffee shop. The world has changed. This place should be full of people, but it can't be at the moment."He says the church's online presence has nearly doubled. Still, other religious institutions have had to navigate through online streaming for the first time."No one in Rabbinical school taught me how to MacGyver a TV station out of my computer, but that's kind of what we're doing," Temple Emmanuel Senior Rabbi Joseph Black said.He says the Jewish community is finding that it's still possible to touch people's lives with online classes and services."In Judaism, the idea of being a part of a community is essential. There are certain prayers that we can only say when we have ten people, and it's called a minion. We're able to do that virtually, and I think people are truly understanding and appreciating the importance of reaching out, being a part of something bigger than themselves even in this time of uncertainty and fear."While Temple Emmanuel can continue most of its rituals online, Muhammad Kolila -- the Imam of the Denver Islamic Center -- says the physical connection is necessary for the Islamic faith."It's fine to pray by yourself at home, a park, or work, but it's not encouraged as praying in the mosque," Imam Kolila said. "It has more rewards in Islam."Usually, there would be more than a hundred people moving in and out of the Mosque for the five daily prayers. But for everyone's safety, the Mosque is now vacant. Imam Kolila says what they can offer online are lectures and reflections to continue spiritual education. Like teaching the importance of choosing generosity over greed and how we can use this time to grow."It's mentioned in the Quran multiple times that when people felt challenged, they would start to become self-aware of how they live their lives." While nobody is sure when this will all be over, religious leaders, as well as followers like Claire Fundingsland, are choosing to focus on the positive."I truly believe that God can do a miracle, and this can turn a big corner tomorrow," Fundingsland said."In times like this, I think sacred space and sacred community is very, very important," Rabbi Black said."Look at your privileges now, and think of people without these privileges," Imam Kolila said."We're not defeated. We're going to be OK. It's going to be tough, we have to take care of each other, but remember we're not alone and God's with us," Pastor Burgen said. 3728

Residents were urged to shelter in place for several hours after an explosion and fire broke out Wednesday at a massive ExxonMobil plant in Texas, injuring 66 people, officials said.The injuries were non-life threatening, plant manager Jason Duncan told reporters. Most involved minor, first-degree-type burns, with the victims treated at a local clinic, he said. Most were ExxonMobil employees or contractors.City officials said via Twitter Wednesday afternoon that the shelter-in-place advisory had been lifted after monitoring failed to detect "any levels of concern" in the air. The fire had been contained by the evening."We realize the people who live here in Baytown and our surrounding communities are worried," Baytown spokeswoman Natasha Barrett told reporters. "We understand that and we've been working hour after hour to check on things, to monitor air quality."The fire occurred at the company's Baytown Olefins Plant, ExxonMobil spokeswoman Sarah Nordin said. The company website describes the complex as one of the largest refining and petrochemical complexes in the world. It's located about 25 miles east of Houston.Barrett said the fire began about 11:07 a.m. local time and the precautionary shelter-in-place was issued about 10 minutes later.The blaze is in a unit that contains polypropylene material and Exxon asked that the shelter-in-place order be issued west of the plant and south of the Texas Spur 330 freeway "out of an abundance of caution," the city of Baytown said via Twitter.Duncan said the fire broke out at a polypropylene recovery unit, where the plastic is purified for production. He said crews were working to shut down the units to isolate the fire source.Duncan said the company is conducting air quality monitoring at the site and fence line, and cooperating with regulatory agencies. He said no adverse environmental effects had been detected.Barrett said city and county officials were also monitoring the air.The cause of the explosion is unknown, he said. 2015

Roughly every 90 seconds, an American is sexually assaulted.“I turned around and saw that there was a man behind me, and he was holding a gun to me,” recalled Nataska Alexenko. “He said ‘This is loaded. Do as I say, or I will blow your brains out.’” On August 6, 1993, Alexenko became one of the estimated 600 people who experienced a sexual assault that day in America.“I just couldn’t believe I was still alive,” Alexenko added.Despite the unimaginable trauma, the then-college student found the strength to go to a hospital and have a rape kit done.“You are poked and prodded, evidence is collected from your body after you have just experienced something so horrific,” said Alexenko.Alexenko found comfort in the belief that her kit would be tested immediately. However, that didn’t happen in her case.“I had no idea my rape kit wasn’t tested,” Alexenko explained. “I had no idea until I got a call nine and a half years later.”However, after the kit was tested, her attacker was found. The delay of justice prompted her to look into how common this experience is for other rape victims.“What I found was gut wrenching,” said Alexenko. She found, at the time, there were hundreds of thousands of rape kits sitting in police evidence rooms around the country. Currently, there are still over 100,000 of those rape kits unopened and untested. That number doesn’t include a dozen states that do not report the status of their rape kits. “There is no other type of forensic evidence that remains untested,” said Karen Friedman Agnifilo, the Chief Assistant District Attorney in Manhattan. “It just doesn’t happen. This is the only one.”“There is no excuse not to test rape kits,” said Cyrus Vance, District Attorney in Manhattan.Their office not only apologized to Natasha Alexenko for the delay in her kit being tested, but they made a public commitment to never have a backlog again.New York City’s Office of Chief Medical Examiner began testing rape kits every day, and still does. The city has now become the leader in the national movement known as End the Backlog.New York City was able to end its rape kit backlog in 2003 but went on to provide funding to more than a dozen other states to help end the backlog there. Now, 55,000 rape kits have been tested, leading to hundreds of perpetrators identified.“It is about treating woman as equal in the eyes of the law,” said Vance. “And if you are not testing rape kits, then we are failing woman.”“Hopefully, one day, we will just look back and say, ‘never again’, but it really has to be a national legislative mandate that no kit can remain untested,” said Agnifilo.So far, a federal mandate like that doesn’t exist. “When I meet survivors whose kits haven’t been processed, and you just see the pain that they are feeling, I mean, how can you let them down?” said Alexenko, “How can you do that to someone who has gone through so much and truly just wants to make sure that the person who harmed them doesn’t go on to harm others?”Alexenko has a non-profit now called 3038

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