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2019 was another bruising year for many American retailers, despite healthy consumers and a strong economy.This year, US retailers announced 9,302 store closings, a 59% jump from 2018 and the highest number since 225
A Denver family is trying to raise million in order to cure their son with a rare genetic disease. Doctors told Amber Freed that her 2-year-old son is one of 34 people in the world to have this rare neurological genetic disease. “The disease is so rare, it doesn’t even have a name,” Freed said. “It’s called SLC6A1, because that is the gene that it effects.” The disease causes Maxwell to have trouble moving and communicating, and soon it will only get worse. “The most debilitating part of the disease will begin between the ages of 3 and 4,” Freed said. “So, we are in a fight against time.”Maxwell has a twin sister named Riley. “I noticed early on that Maxwell wasn’t progressing as much as Riley,” Freed said. “I noticed he couldn’t use his hands. The doctors told me that every baby can use their hands. That’s when I realized there was something wrong with him.”After multiple visits to the doctor, Freed was able to find a genetic specialist to give Maxwell a diagnosis. “He looked at me and said, ‘Something is very wrong with your son. I don’t know if he’s going to live,’” Freed said. “My soul was just crushed. It was a sadness I didn’t even know existed on earth. You never think something like this could happen. I left my career, and I had no other choice but to create my own miracle and to find a treatment forward to help Maxwell and all those others like him.” Freed searched for scientists trying to create a cure, which she found at the University of Texas Southwestern Medical Center in Dallas. “We’re working with diseases where kids are born with a defective gene,” said Steven Gray, an associate professor at UTSW in pediatrics. “Our approach is to replace that gene to fix the condition at the level of their DNA. We’re taking the DNA that those patients are missing and packaging that into a virus and use that virus as a molecular delivery truck to carry those genes back in their body and fix their DNA.” “It’s a rare disease, no one has ever heard of it,” Freed said. “But one rare disease messed with the wrong mother.” Freed said she has raised million to help with research for the cure and will need an additional million, in order to let Maxwell and many others continue to enjoy life. “I want Maxwell to have every opportunity that children should have in this life,” Freed said. “When he is having a good day, I just try and soak him in as much as I can. We don’t take anything for granted in this house.” If you want to help donate for the cure, you can do so by visiting 2535

A high school cheerleading team in North Carolina was put on probation by the state athletic association after the team held up a "Trump 2020" sign at a football game earlier this year.The photo, shared on social media among school parents and conservative groups, shows a cheerleader and two students in what appear to be MAGA hats holding a "Trump 2020: MAKE AMERICA GREAT AGAIN" banner. A number of other cheerleaders are posing near the sign.According to 471
@SouthwestAir @MCO my flight to Washington DC has been delayed for almost 2 and a half hours and I was getting HEATED until this gate agent started playing games with everyone waiting to pass the time and now I’m like I’ll wait all damn night if you keep this up ?? #amazing pic.twitter.com/K0WnThxcW6— Kristen Dundas (@kdunds13) August 23, 2019 357
A baseball bat used by legendary player Babe Ruth to hit his 500th career home run has sold at auction for over million.An unnamed bidder on Saturday paid ,000,800 for the bat, which Ruth held to smash his 500th homer while playing for the 257
来源:资阳报