成都哪里看雷诺氏综合症看得好(成都脉管畸形科医院医院) (今日更新中)

SAN DIEGO (KGTV) — Governor Gavin Newsom’s vaccine safety task force will have to work quickly once the FDA announces a decision on Pfizer’s COVID-19 vaccine candidate.The 11-member panel, officially called the Scientific Safety Review Workgroup, has been tasked with reviewing the safety and efficacy of vaccine trials and rendering a recommendation on their use in California.The workgroup has a difficult mission: review the data thoroughly enough to offer a recommendation independent from the FDA, but do it fast enough to avoid delaying distribution of the vaccine.Pfizer’s emergency use authorization application spans thousands of pages.The workgroup has already reviewed Pfizer’s early-stage clinical trial data from phases 1 and 2 and found no cause for concern, Governor Gavin Newsom said. They’re still waiting to get their hands on the all-important Phase 3 data, which included thousands of participants.Panel member Dr. Rodney Hood, the president of the Multicultural Health Foundation, acknowledged the task force will have to complete its review of the Phase 3 data “very, very quickly.” Dr. Hood is one of two members from the San Diego region, along with Dr. Mark Sawyer of Rady Children’s Hospital.“We certainly don't want to introduce any unnecessary delay in the vaccine being available to Californians,” Dr. Sawyer said.The FDA has scheduled a meeting of its vaccine advisory committee, known by its acronym VRBPAC (pronounced verb-pack), on Dec. 10. The agency said it will make Pfizer’s Phase 3 data available at least two days before that meeting.At the end of that meeting, a group of about 20 experts on the advisory committee will vote on whether to recommend emergency authorization of the vaccine. The FDA is expected to issue a decision shortly after, although the agency does not have to abide by the advisory committee’s recommendation.“The California committee is on notice to be ready for a meeting either later in the day on the 10th or on December 11,” said Dr. Sawyer.Dr. Sawyer was recently added to VRBPAC, so he will cast a vote on whether to recommend approval of the vaccine at the national level before participating in California’s process.“It is going to take a few days for the vaccine to really start flowing,” he said. “I don't think the [California] committee is going to introduce extra delay.”The California committee has promised to issue its decision within 24 hours of the FDA’s to avoid slowing down distribution, but that means the members may have as few as three days to review the safety and efficacy data.Federal regulators will spend about three weeks reviewing the thousands of pages of data submitted as part of Pfizer’s application. VRBPAC and the California Scientific Safety Review Workgroup will render decisions based on summaries prepared by the FDA, Dr. Sawyer said.Both doctors say they have confidence in the FDA’s process and acknowledge it would be very unlikely for the California workgroup to break with the agency’s recommendation. They said the mission of their review is to add an extra layer of verification after complaints the Trump administration was exercising political pressure on the FDA.“I think the governor foresaw that it was going to be very important that the general community accept these vaccines, assuming they're approved and are safe and effective, because otherwise we're not going to get out of this pandemic,” Dr. Sawyer said.The doctors say they want to make sure that community acceptance extends across all demographics, so they’ll be looking closely at the numbers to see if various ethnic or racial groups had different responses to the vaccine.Based on research on past vaccines, a differential response is not expected, Dr. Hood said. However, COVID-19 does strike Latinos and African-Americans more severely, making vaccine acceptance among minority communities all the more critical.“I want to look at the data, get an assessment of risk-benefit and the question I ask is, would I take it? Number one. Number two, if I would take it, would I recommend it to my family?” he said.The doctors said they will also closely examine reports of side effects.Early data suggests both Pfizer and Moderna’s candidates have somewhat harder-hitting side effects than the typical flu vaccine. Dr. Sawyer compared the side effects to the recent shingles vaccine.“Your arm hurts for a day or two. You may not feel well. You may feel a little bit under the weather for the first 24 hours. You could even have a mild fever or headache,” he said, noting those symptoms typically resolve within 24 to 48 hours based on the data available so far.“That's actually a good sign. You want that to happen,” he added.Those sorts of short-term side effects are signs the body is building a strong immune response. They’re evidence the vaccines work as well as advertised, but the doctors say they won’t know for certain until they review the final numbers. 4949

SAN DIEGO (KGTV) — Gusty offshore winds and high temperatures will work their way back into San Diego County this week.San Diego Fire-Rescue is expected to beef of staffing Sunday through Monday in anticipation of the Santa Ana wind event forecasted to start Sunday night.Sunday, winds will turn offshore and become gusty along coastal slopes, according to the National Weather Service. High pressure will add to the warming, increasing the risk for wildfires.NWS forecasts a high of 76 degrees and low of 58 degrees, Sunday.WEATHER: Check updated conditions across San Diego County Those temps rise Monday, with a forecasted high of 85 degrees and low 62 degrees. Monday will see winds shift east, as winds shifts through the coastal slopes and into San Diego County mountains and foothills. Wind speeds may sit at 15-25 mph, with gusts up to 30-40 mph. Humidity levels will hover near 10%, elevating the fire danger.Breezy conditions are expected to continue into Tuesday morning, before weakening that afternoon. Low humidity and warm temperatures, with periods of easterly winds, will be common throughout the week, NWS says. 1138

SAN DIEGO (KGTV) -- Home sales in San Diego are starting to see a dramatic decrease, according to a new report by CoreLogic.Year-to-year, home sales fell nearly 18 percent from September of 2017 to September of 2018. From August to September of this year, home sales fell nearly 22 percent. Since 1988, the average change in sales between August and September is only 9.8 percent.“The nearly 18 percent year-over-year drop in Southern California home sales this September was the largest for any month in almost eight years,” said Andrew LePage, a CoreLogic analyst.Also in September, sales of newly-built homes in Southern California were 46.6 percent below the September average since 1988.The drop in home sales is due to higher prices and rising mortgage rates, according to CoreLogic. Those factors are pricing out some would-be buyers and prompting others to wait and see what happens with the housing market.The median home price in San Diego County in September of 2018 was 5,000, up nearly eight percent from the same time last year, however, the median price fell by 1.4 percent from August to September of 2018.“Price growth is moderating amid slower sales and more listings in many markets,” LePage said. “This is welcome news for potential homebuyers, but many still face a daunting hurdle – the monthly mortgage payment, which has been pushed up sharply by rising mortgage rates.” 1405

SAN DIEGO (KGTV) — For several months, San Diegans were invited to weigh in on the Port Master Plan proposal. It's the Port of San Diego's first comprehensive update in nearly 40 years, aiming to reflect changes in the needs and priorities of the region. The Port manages 34 miles of San Diego Bay and Waterfront along Chula Vista, Coronado, Imperial Beach, National City, and San Diego. When the Port published the proposed master plan in April, several communities voiced major concerns; two of the most vocal being Coronado and Point Loma residents. "We have this little slice of history, and I think it's our obligation to preserve, so it's enjoyed generations to come," said Cameron Lilley, a multi-generational Point Loma native.For months, Lilley has been garnering community support in opposition to some of the proposals impacting Shelter Island. "We started digging into it and quickly realized that there were so many points that really didn't consider the locals in the restructure of our community," said Lilley. Some of their primary concerns:Up to 1600 new hotel rooms70,000 square feet of retail and restaurant spaceRemoving private and historic docksThe Port received nearly 3,000 comment letters in response to its initial proposal. On Monday Port commissioners listened to public comment and made recommendations to staff.Direction to staff for the Shelter Island Planning District:No new hotel rooms on Shelter Island, move them to Harbor Island 30-foot height limit, consistent with City of San Diego height limitKeep Marlin Club at current location La Playa Piers - keep piers the way they are; open to the public with gangways and floating docks to remain privateLa Playa Yacht Club - no perimeter walkway, pursue other methods to provide public access to the areaScott Street - no reconfigurationAdd clarifying language:While it was never the Port’s intent to build a restroom on the La Playa Trail or at the trailhead, add language to clarify that no restrooms will be built Clarify the Port’s intent for the La Playa Trail to maintain it in its natural stateClarify the Port’s intent to maintain and protect current maritime usesPort staff will bring a revised proposal back to the table in six months, giving the public another opportunity to weigh in. 2289

SAN DIEGO (KGTV) - Family and friends of a disabled Clairemont woman are making a plea for the arrest of a hit-and-run driver who left her with serious injuries.Last week, a beaming Delores Odom appeared at a surprise party for her 59th birthday. One of the attendees was her friend and neighbor Maritza Gates. "She was so happy that day. It breaks my heart to see her in the hospital now in so much pain," said Gates. On Saturday just before 6:30 p.m., Odom decided to take a walk to grab dinner. She was crossing westbound on Genesee Avenue in the south crosswalk when she was hit by a vehicle that had been going westbound on Derrick Drive and made a left turn to southbound Genesee Avenue, according to police.Odom's daughter Brianna says her mother broke her back in two places. Odom has feeling in her toes, but still faces possible paralysis and requires complicated back surgery. Her recovery and rehabilitation is made more challenging because of a decades-old diagnosis of multiple sclerosis. "There's a special place for people like that. I don't understand how you could hurt someone and then leave them. My mom is one of the nicest people ever. You don't know someone's story when you leave them to die on the street," she said.Police say there is no description of the vehicle and are looking for witnesses. Anyone with information is asked to call Crime Stoppers at 1-888-580-8477.A Gofundme campaign has been set up to help with expenses. 1462

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