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Epidiolex, the first cannabis-based medication approved by the US Food and Drug Administration, is now available by prescription in all 50 states.The twice-daily oral solution is approved for use in patients 2 and older to treat two types of epileptic syndromes: Dravet syndrome, a rare genetic dysfunction of the brain that begins in the first year of life, and Lennox-Gastaut syndrome, a form of epilepsy with multiple types of seizures that begins in early childhood, usually between ages 3 and 5."Because these patients have historically not responded well to available seizure medications, there has been a dire need for new therapies that aim to reduce the frequency and impact of seizures," said Justin Gover, CEO of GW Pharmaceuticals, the maker of Epidiolex, in a written statement. "We are committed to ensuring that these patients can access this novel cannabinoid medicine that has been thoroughly studied in clinical trials, manufactured to assure quality and consistency, and is eligible to be covered by insurance for appropriate patients." 1063

ESCONDIDO, Calif. (KGTV) -- Authorities are offering a large reward for information leading to the arrest of a suspect accused in an arson attack on a mosque in Escondido. The FBI announced the ,000 reward at a news conference Thursday. The FBI, Bureau of Alcohol, Tobacco, Firearms and Explosives as well as local authorities are investigating the incident. RELATED: Graffiti referencing New Zealand left at Escondido mosque after possible arsonThe arson happened at the Islamic Center of Escondido on West 6th Avenue around 3 a.m. on March 24. A handful of worshipers were inside at the time and were able to extinguish the flames before any significant damage was done. RELATED: Security tight at San Diego area mosques after Sunday's arsonWhen police arrived, they found a message in graffiti referencing the shootings at mosques in New Zealand. 861

Everything should be working properly now! We are continuing to monitor the situation. Thank you all for your patience and our sincere apologies for disrupting your day.— Zoom (@zoom_us) August 24, 2020 210

ESCONDIDO, Calif. (KGTV) — In a display of solidarity with protesters, Escondido officers were seen taking a knee with protesters during a demonstration against police violence on Monday.Photos showed the officers alongside protesters demonstrating against racism, police brutality, and calling for justice for George Floyd, a black man who died in police custody in Minneapolis.Long-time resident Vanessa Reyes attended the demonstration which happened outside of Escondido Police Department headquarters. She captured the profound moment in a series of photos she later shared with 10News.“It was very emotional, it was very eye opening for me.”The mother of four said she wanted to document the protests for her children, ages 7- to 22-years-old. Not knowing what to expect, she decided to keep her children home while she snapped images of the demonstration.“I went out there to support the black community and take pictures because I really want to have pictures for my kids to show them this is going to be history, this is real, this is what’s going on.”Reyes described the demonstration as peaceful and emotional, though some times rowdy.“The younger kids, maybe like the 20-25 year old’s, they were very, very involved and wanted to be heard, and the chief of police was willing to let them be heard," said Reyes. “Everybody just wanted to be heard and there was so much emotion and the Escondido Police sat there and listened.”At one point during the protest, Reyes said the crowd, comprised of people of various races, moved towards the police skirmish line. “When we first got there all the officers were across the street, then all of a sudden the protesters moved towards the officers," said Reyes.The tense situation was de-escalated when demonstrators struck a conversation with an officer.“A group of protesters got together and asked the officers if they wanted to take a knee and have a moment of silence for George Floyd and they didn’t hesitate.”Reyes began taking photos to capture one of San Diego's most powerful moments of these demonstrations that saw a weekend marred by violence and riots across the county.The officers, dressed only in their regular uniforms, joined the crowd.“That moment was extremely emotional. You could tell that they [officers] were very genuine and you could tell they really want to make peace and everything better for us.”Unlike some of the chaotic confrontations witnessed in other parts of the country, Reyes said demonstrators and police officers were respectful of each other, and that the police chief was actively encouraging the crowd to share their voice.“Officers tried to ask everybody what could they do.”The scene was similar to a display caught on Sunday in downtown San Diego, where protesters exchanged fist bumps and handshakes with officers. Other moments of unity between police and demonstrators have been captured around the nation.In a statement, an Escondido Police officer said:"Last night I, as well the citizens of Escondido were witness to a peaceful, passionate, justified protest. I want to thank our community for your powerful display of protest, in the peaceful yet profound manner it was delivered.I witnessed 'the few' agitators that attempted to hijack the event with violent and destructive means, met by 'the many' of our community members, protest groups and participants, who thwarted all efforts demanding peace and civility.For this I extend my deepest gratitude. Thank you for supporting us as we were doing our best to support you. We hear you, we stand and or kneel with you and through these difficult times we will not wavier in our mission to serve and protect you.I truly believe it is you, the people, that make this the City Of Choice!"Protests across the county and around the nation began this week after video surfaced showing a Minneapolis officer kneeling on Floyd's neck for nearly 10 minutes. Floyd's death while in-custody sparked nationwide calls for police reform. 3989

Fashion designer Hubert de Givenchy, a pioneer in high-end ready-to-wear clothing and famous for styling Audrey Hepburn's little black dress in "Breakfast at Tiffany's," has died at the age of 91, the House of Givenchy confirmed on Monday via its official Twitter account."The House of Givenchy is sad to report the passing of its founder Hubert de Givenchy, a major personality of the world of French Haute Couture and a gentleman who symbolized Parisian chic and elegance for more than half a century. He will be greatly missed," the company announced.His longtime partner, former haute couture designer Philippe Venet, revealed in a statement to AFP that Givenchy died in his sleep on Saturday.Givenchy entered the world of fashion in 1944 at the age of 17, training under Parisian designer Jacques Fath.Before long, he had moved on to designing for several major fashion houses including Robert Piguet, Lucien Lelong and Elsa Schiaparelli.Givenchy was in his mid-20s when he threw caution to the wind and launched his eponymous label in 1952. He maintained low overhead costs to keep down the prices of his designs.His first collection -- which championed the concept of separates and featured flawlessly detailed embroidered pieces, chic silk prints and sophisticated ball gowns -- immediately drew international recognition.From the off, he blazed a trail of innovation in the industry starting with his "Bettina blouse," named for popular French 1950s supermodel Bettina Graziani, which reintroduced tailored shirts into high fashion.But Givenchy was perhaps best known for his decades-long friendship with his muse Audrey Hepburn, which blossomed while she was filming her 1954 hit "Sabrina."Givenchy continued to style her outfits for "Breakfast at Tiffany's," "Funny Face" and "How to Steal a Million" and their friendship would endure until Hepburn's death from cancer in 1993."It was a kind of marriage," Givenchy told the UK's Daily Telegraph newspaper in 2015. "Little by little, our friendship grew and with it a confidence in each other," he added."There (was never) any criticism of the other person, no upsets."Enduring legacyOver the years, the haute couturier became a firm favorite of some of the world's most glamorous and highly admired A-listers.When Jackie Kennedy accompanied her husband to Paris in 1961, she turned to Givenchy to help dress her."It was not the same relationship or friendship that I had with Audrey," the couturier said in 2012 of his work with Kennedy. "The American people felt emotion for Jackie, but they preferred to have an American couturier design her dresses when they came to France for a state visit. Jackie asked for more than 10 or 15 pieces, saying 'I don't know if I can be dressed by a French designer.'"He continued: "We did all the fittings in secret. Then after the event at Versailles, Jackie sent me a little postcard to tell me that General de Gaulle gave her a very nice compliment. He said, 'Madame, this evening you look like a Parisienne.'"During his illustrious career, Givenchy also styled the likes of Elizabeth Taylor and Princess Grace of Monaco.Today, his label continues to be relevant and innovative, remaining incredibly popular with celebrity fans including Beyoncé, Kanye West and Rihanna. Beyoncé's love of the fashion house's style is well-known, with her having worn its creations to the last five Met Galas she attended between 2012 and 2016 (she didn't attend the gala in 2017). Fashion elite mourn 3498

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