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NEW YORK (AP) — In a litmus test for American moviegoing in the pandemic, Christopher Nolan’s “Tenet” brought in an estimated .2 million through the holiday weekend in U.S. and Canadian theaters. The result could be greeted as either the rejuvenation of U.S. cinemas — more Americans went to the movies this weekend than they have in nearly six months — or a reflection of drastically lowered standards for Hollywood’s top blockbusters given the circumstances. About 70% of U.S. movie theaters are currently open. Those in the country’s top markets, Los Angeles and New York, remain closed. Warner Bros. has emphasized that the usual opening-weekend calculus is out the window. Few onlookers felt it was possible to gauge how “Tenet” would open. The film, which cost 0 million to make and at least 0 million to market, will need to get close to 0 million to break even.The Walt Disney Co. also debut its 0 million live-action “Mulan” remake, but did so in a on-demand purchase for Disney+ subscribers. 1028

None of the countries that make up the G20 group of major world economies is on course to adequately reduce climate change, with 82% of the bloc's energy supply still coming from fossil fuels, a new report has warned.Of the countries, only India has set targets that would keep global temperature rise below 2 degrees Celsius, the upper limit recommended by the Paris Climate Agreement, if adopted globally.Overall, the world is heading for a 3.2-degree rise, the organization Climate Transparency said, in an analysis of the G20's current emissions-cutting targets for 2030 published Wednesday.Targets set by the worst offenders -- Russia, Saudi Arabia and Turkey -- would lead to a rise of more than 4 degrees if they were adopted worldwide, the report added.The G20 comprises representatives from Argentina, Australia, Brazil, Canada, China, the European Union, France, Germany, India, Indonesia, Italy, Japan, Mexico, Russia, Saudi Arabia, South Africa, South Korea, Turkey, the United Kingdom, and the United States.The landmark Paris Agreement, drafted in 2015, resulted in an aim to keep global warming below 1.5 degrees compared to pre-industrial levels, with 2 degrees set as an upper limit.But the report cautions that those targets are virtually impossible to reach at current rates. It follows similar warnings made last month by the Intergovernmental Panel on Climate Change (IPCC), which found that the earth will reach the crucial 1.5 degree threshold as early as 2030."The G20 economies actually need to cut their emissions by half by 2030 to keep warming below 1.5°C," said Jan Burck, senior adviser at equality NGO Germanwatch, one of the report's authors. Germanwatch is one of 14 partners that make up Climate Transparency."But instead of responding to the urgency of climate change, the G20 countries continue to pour money into factors that drive climate disruption, like fossil fuel subsidies, instead of taking stronger action," he added.G20 countries account for around 80% of the world's global greenhouse gas emissions, according to the World Resources Institute.  2104

New research suggests that antibodies the immune system makes to fight the new coronavirus may only last a few months in people with mild illness, but that doesn’t mean protection also is gone or that it won’t be possible to develop an effective vaccine.“Infection with this coronavirus does not necessarily generate lifetime immunity,” but antibodies are only part of the story, said Dr. Buddy Creech, an infectious disease specialist at Vanderbilt University. He had no role in the work, published Tuesday in the New England Journal of Medicine.The immune system remembers how to make fresh antibodies if needed and other parts of it also can mount an attack, he said.Antibodies are proteins that white blood cells called B cells make to bind to the virus and help eliminate it. The earliest ones are fairly crude but as infection goes on, the immune system becomes trained to focus its attack and to make more precise antibodies.Dr. Otto Yang and others at the University of California, Los Angeles, measured these more precise antibodies in 30 patients diagnosed with COVID-19 and four housemates presumed to have the disease. Their average age was 43 and most had mild symptoms.Researchers found that the antibodies had a half-life of 73 days, which means that half of them would be gone after that much time. It dovetails with a previous report from China also suggesting antibodies quickly fade.The results “call for caution regarding antibody-based ‘immunity passports,’ herd immunity, and perhaps vaccine durability,” the California authors write.That’s true, Creech said, but other parts of the immune system also help confer protection. Besides churning out antibodies, B cells develop a memory so they know how to do that again if needed.“They would get called into action very quickly when there’s a new exposure to the virus. It’s as if they lie dormant, just waiting,” he said.Other white blood cells called T cells also are better able to attack the virus the next time they see it, Creech said.Although circulating antibodies may not last long, what we need to know is if and how people remake antibodies if exposed to the coronavirus again and if they protect against another infection, Alison Criss, an immunologist at the University of Virginia, wrote in an email. “We also need to know if there is a protective T cell response” that reappears.Vaccines, which provoke the immune system to make antibodies, might give longer-lasting protection than natural infection because they use purified versions of what stimulates that response, she noted.Creech agreed.“This shouldn’t dissuade us from pursuing a vaccine,” he said. “Antibodies are only a part of the story.”___Marilynn Marchione can be followed on Twitter at http://twitter.com/MMarchioneAP___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2967

NOBLESVILLE, Ind. — President Donald Trump thanked an Indiana teacher for helping thwart a school shooting on Friday at Noblesville West Middle School outside of Indianapolis."Thanks to very brave Teacher & Hero Jason Seaman of Noblesville, Indiana, for his heroic act in saving so many precious young lives. His quick and automatic action is being talked about all over the world!" Trump tweeted.Seaman is a science teacher at the school, and multiple students on the scene say Seaman was the teacher who helped stop the shooter.His mother, Kristi, says her son was shot in the abdomen, the hip and the forearm, according to her Facebook page. She says Jason is out of surgery and is "doing well."According to his LinkedIn page, Seaman has been a science teacher at Noblesville schools since July 2014. He is also the head football coach for the seventh-grade team.A student who was in the classroom at the time of the incident credited the teacher with stopping the shooting from being worse than it was.Southern Illinois University football also tweeted about Seaman. He was a defensive end for the Saluki's from 2007-10. 1141

NEW YORK (AP) — There is still plenty of life in Stephenie Meyer's "Twilight Saga." Meyer says she is planning at least two more books in her mega-selling vampire series. Meanwhile, the author's long-awaited "Midnight Sun" sold more than 1 million copies in its first week, the publisher Little, Brown Books for Young Readers announced Thursday. 354

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