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WASHINGTON, Nov. 18 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday revoked its approval of Avastin for treating the breast cancer after concluding that the drug has not been shown to be safe and effective for that use.Avastin will still remain on the market as an approved treatment for certain types of colon, lung, kidney and brain cancer."After reviewing the available studies it is clear that women who take Avastin for metastatic breast cancer risk potentially life-threatening side effects without proof that the use of Avastin will provide a benefit, in terms of delay in tumor growth, that would justify those risks," FDA Commissioner Margaret Hamburg said in a statement. "Nor is there evidence that use of Avastin will either help them live longer or improve their quality of life. "Avastin's risks include severe high blood pressure; bleeding and hemorrhaging; heart attack or heart failure; and the development of perforations in different parts of the body such as the nose, stomach, and intestines.Avastin was approved for metastatic breast cancer in February 2008 under the FDA's accelerated approval program, which allows a drug to be approved based on data that are not sufficiently complete to permit full approval. After the approval, the drug's sponsor, Genentech, completed two additional clinical trials and submitted the data from those studies to the FDA. These data showed only a small effect on tumor growth without evidence that patients lived any longer or had a better quality of life compared to taking standard chemotherapy alone -- not enough to outweigh the risk of taking the drug.FDA's Center for Drug Evaluation and Research, which is responsible for the approval of this drug, ultimately concluded that the results of these additional studies did not justify continued approval and notified Genentech it was proposing to withdraw approval of the indication.Genentech did not agree with the Center's evaluation of the data and, following the procedures set out in FDA regulations, requested a hearing on the Center's withdrawal proposal, with a decision to be made by the Commissioner. That two-day hearing, which took place June 28-29, included recommendations from the FDA 's Oncologic Drugs Advisory Committee, voting 6-0 in favor of withdrawing approval of Avastin's breast cancer indication.

TEHRAN, Oct. 9 (Xinhua) -- Iran is going to launch domestically- built Navid satellite by Safir satellite launcher by the end of March 2012, the semi-official Mehr news agency reported on Sunday.Navid (promise) is a research satellite and is currently undergoing pre-launch tests, said the report without further details.In June, Iran put the Rasad (surveillance) satellite in the orbit to render images to the country.Iran put a satellite into orbit in 2009 and sent some small animals into space in 2010. It plans to send man into space by 2020.

BEIJING, Oct. 24 (Xinhuanet) -- There is no evidence to prove that using a cell phone can increase the risks of brain cancer, suggested a lastest study by Danish researchers.To arrive at the result, the researchers examined the health records from 1990 to 2007 for 358,403 Danish cell phone plan subscribers.They found that among people using cell phones for as long as 13 years or more, the cancer risks were almost the same as for non-subscribers.The finding, published in the British Medical Journal last week, alleviated the fear among the world's 5 billion cell phone users.Five months ago, a statement from the World Health Organization's International Agency for Research on Cancer (IARC) sparked fear in cell phone users around the world because it said that cell phone use might cause brain cancer.However, the finding could not rule out the risk of brain cancer triggered by heavy use of cell phones, admitted Patrizia Frei of the Danish Cancer Society's Institute of Cancer Epidemiology, lead author of the study.Frei added, cited by CNN, "There are still some open questions, about greater amounts of use, and about the effects on children."The IARC did not give formal response to the study, but it offered some ways for cell phone consumers to reduce possible risks months ago.Texting and using hands-free sets for voice calls lower exposure to potentially harmful radiation, compared to device-to-ear voice calls, by at least 10-fold, IARC stated, reported by the New York Daily News.

BEIJING, Dec. 28 (Xinhuanet) -- China started to run its own satellite positioning system, Beidou, on Tuesday as the country climbed the global tech ladder and challenged the monopoly of the West. Beidou, or Big Dipper, the domestic version of the US Global Positioning System (GPS), started providing navigation, positioning and timing data on a pilot basis to China and the neighboring area for free on Tuesday, Ran Chengqi, director of the China Satellite Navigation Office, said. The system, with 10 orbiting satellites, covers an area from Australia in the south to Russia in the north. Signals can reach the Xinjiang Uygur autonomous region in the west and the Pacific Ocean in the east, Ran said. With six more satellites to be launched next year, the system will cover a wider area and eventually the entire globe by 2020 with a constellation of 35 satellites, he said. The accuracy of the positioning service will also improve as more satellites orbit. During the trial run Beidou can offer positioning to within 25 meters but when the system is officially launched next year accuracy will be enhanced to within 10 meters, he said. With the system operational China is the third member of an elite group, along with the US and Russia, to develop a satellite navigation system. The US spent 20 years and more than billion on the GPS. Completed in 1994, the system has 24 navigation satellites and is widely used around the world. Beidou has its own unique features, Ran said. "It not only tells users where they are and what time it is but also allows users to tell others the information through short messages," Ran said, adding that this feature is being considered by other systems. Russia's Glonass system achieved a 24-satellite constellation in 1996 but succumbed to funding problems. The rebuilding of the Glonass system is almost finished and Russian media reported that the system resumed service earlier this month. The European Union and the European Space Agency are building the Galileo satellite navigation system. Japan and India also intend to build independent regional navigation systems. "Countries build their own systems because owning an independent satellite navigation system is important to economic development and national security," said Pang Zhihao, deputy editor-in-chief of the monthly publication Space International. There have long been concerns that the US might take its dominant GPS offline in certain international emergencies. Ran said that the Beidou system will be "helpful" to national defense. An "independent and controllable" satellite navigation system can guarantee national economic development as well as scientific and industrial strength, he said. China started to reduce its reliance on the GPS in 2000, when it sent an experimental pair of positioning satellites into orbit. But Ran stressed that Beidou is "built for the world", as the compatibility of various systems enhances reliability for users. "If you only use GPS there will be blind spots. But from demonstrations I saw recently, receivers that are compatible with Beidou will overcome these problems," he said. He encouraged enterprises at home and abroad to join the research and development of application terminals compatible with Beidou. The office put a test version of the system's Interface Control Document online on Tuesday, which is a technical document vital for the manufacturing and development of receivers and chips. The prospects for the country's satellite navigation industry look bright, experts said. Analysts estimated that around 2020 the industry's output will reach 0 billion globally, including 400 billion yuan ( billion) to 500 billion yuan from China. According to the 2011 Report on Application of Geosaptial Information in China released on Monday, the number of satellite navigation application terminals in China has grown from less than 100,000 in 2000 to more than 10 million in 2009. The number is expected to reach 340 million by 2015. An insider said a compatible receiver for car use costs 1,600 yuan to 3,000 yuan, higher than a GPS receiver. "Chips supporting both GPS and Beidou systems have been developed, and terminals have been produced. There are no technical hurdles for the industry," said Han Shaowei, CEO of Beijing-based Unicore Communications Inc, a major navigation chip and core component provider. Beidou application terminals have been put into use in vehicles, such as government cars in Guangdong province. Ran said that private terminal makers in Guangdong are testing their receivers on the road, and the products seem stable. "The price of the compatible terminals is expected to be slashed next year," he said.

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