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SAN FRANCISCO, Sept. 13 (Xinhua) -- Researchers in San Francisco, U.S. have found in a latest study that bisphenol A (BPA) and methylparaben, two chemicals commonly used in consumer products, can interfere with the breast cancer drugs, local media reported on Tuesday.In the study, doctors from California Pacific Medical Center in San Francisco found that healthy breast cells from high-risk patients started to find ways to bypass breast cancer drugs after they were exposed to BPA and methylparaben in the lab.The cells exposed to the two chemicals kept growing and didn't die after they were introduced with Tamoxifen, a current standard drug therapy for female breast cancer and most common used treatment for male breast cancer, Dr. William Goodson, lead author of the study, told San Francisco Chronicle.Goodson said that BPA and methylparaben not only mimic estrogen 's ability to drive cancer, but appear to be even better than the natural hormone in bypassing the ability of drugs to treat it. The finds have been published online in the British medical journal Carcinogenesis.The research shows more evidence of safety issues of BPA, a chemical primarily used to make plastic baby bottles, food containers, household electronics and etc, as well as the less known methylparaben, a chemical preservative used in cosmetics and other personal care products.The researchers noted that the breast cancer rates have been growing by about the same amount in men as in women over the past three decades. Scientists have been looking at environmental causes for the disease and wondering where the hormones are coming from.Goodson said BPA and methylparaben are used so widely and even found in household dust, noting that it is still unknown whether the effects of exposure to the chemicals are reversible.Since 2008, several governments issued reports questioning the negative health effects of BPA, especially raising concerns regarding exposure of fetuses, infants and children. BPA use has been banned in baby bottles in a lot of countries and regions.As for methylparaben, the U.S. Food and Drug Administration said on its website that "at the present time there is no reason for consumers to be concerned about the uses of cosmetics containing parabens (including methylparaben)."

WASHINGTON, Sept. 26 (Xinhua) -- Older people with low blood levels of vitamin B12 markers may be more likely to have lower brain volumes and have problems with their thinking skills, according to researchers at Rush University Medical Center in Chicago.The results of the study will be published Tuesday in Neurology, the medical journal of the American Academy of Neurology.Foods that come from animals, including fish, meat, especially liver, milk, eggs and poultry are usual sources of vitamin B12.The study involved 121 older residents of the south side of Chicago over the age of 65. They had blood drawn to measure levels of vitamin B12 and B12-related markers that can indicate a B12 deficiency. The same subjects took tests measuring their memory and other cognitive skills.An average of four-and-a-half years later, MRI scans of the participants' brains were taken to measure total brain volume and look for other signs of brain damage.Having high levels of four of five markers for vitamin B12 deficiency was associated with having lower scores on the cognitive tests and smaller total brain volume."Our findings definitely deserve further examination," said Christine Tangney, associate professor at Rush University Medical Center and lead author of the study. "It's too early to say whether increasing vitamin B12 levels in older people through diet or supplements could prevent these problems, but it is an interesting question to explore. Findings from a British trial with B vitamin supplementation are also supportive of these outcomes."On the cognitive tests, the scores ranged from -2.18 to 1.42, with an average of 0.23. For each increase of one micromole per liter of homocysteine -- one of the markers of B12 deficiency -- the cognitive scores decreased by 0.03 standardized units or points.Tangney noted that the level of vitamin B12 itself in the blood was not associated with cognitive problems or loss in brain volume. "Our findings lend support for the contention that poor vitamin B12 status is a potential risk factor for brain atrophy and may contribute to cognitive impairment," said Tangney.

BERLIN, July 26 (Xinhua) -- German national disease control center said on Tuesday that the country's deadly E. coli outbreak has been over, as no new case reported in the last three weeks.The Robert Koch Institute (RKI) said the last case related to the E.coli outbreak was reported on July 4.As a three-week-period would cover the disease's incubation time, diagnosis time and the time for the transfer of a case, this virtually means an end of the outbreak."The largest EHEC outbreak is over in Germany," said RKI President Reinhard Burger. "I pay tribute to people who have joined in the great work, making investigation and looking after the patients."The RKI said Germany would keep watching the deadly EHEC O104: H4 intensively and asked people to pay attention to personal and food hygiene, as individual infection still cannot be ruled out.This round of outbreak has claimed 52 lives and affected more than 4,000 people since early May.The source of this disease was first believed to be cucumbers and tomatoes from Spain, and then was locked onto bean sprouts grown in a farm near Hamburg in the state Lower Saxony. Later European authorities said one batch of fenugreek seeds from Egypt was probably the source.

KATHMANDU, Aug. 3 (Xinhua) -- Two glaciers in Nepal that shrank at an accelerated rate in the past 10 years compared to preceding decades will inevitably disappear from rising temperatures as no fresh snow supply is expected for them, a new research by Japan's Nagoya University says.According to Wednesday's Republica daily, the masses of the Yala glacier of Langtang Himal in central Nepal and the AX010 glacier of Shorong Himal in the Khumbu region shrank annually by 0. 8 meters and 0.81 meters respectively in the 2000s, which was a significant acceleration from the 0.68 and 0.72 meters of shrinkage per year between 1970 and 1990, said findings of the research published in a journal of the National Academy of Sciences of the United States on Tuesday."If the trend since the 1990s continues for the Yala and AX010 glaciers, the disappearance of these glaciers is inevitable because they are about to lose their accumulation areas, thus, no snow supply is expected for these glaciers," says the research conducted by Koji Fujita and Takayuki Nuimura.The researchers also found that while the shrinking of glaciers has accelerated in humid environments, the opposite is true for those in arid environments. The shrinking of Rikha Samba glacier located in the Kaligandaki Hidden Valley slowed from 0.57 meters per year between 1970 and 1990 to 0.48 meters per year in the 2000s."A comparison of the mass balance results and annual precipitation reveals that glacier wastage has been accelerated in humid environments but suppressed in an arid environment," the research says.Apart from environment, altitude also appears to play a role in the lifespan of glaciers, the researchers say. Rikha Samba is located at an altitude of 5,700 meters where loss of mass from melting could be compensated to some extent by collection of snowfall.The Yala glacier and AX010, on the other hand, are located at lower altitudes of 5,400 meters and 5,200 meters respectively.

SHENZHEN, June 4 (Xinhua) -- Chinese scientists who have fully sequenced the genome of the new E. Coli spreading through Europe said Saturday they found genes in the bacteria that gave it resistance to eight classes of antibiotics.Researchers with the Beijing Genomics Institute, the world's largest DNA sequencing center, have found genes in the newly identified 0104 strain of E. Coli bacteria that made it resistant to major classes of antibiotics including sulfonamide, cephalothin, penicillin and streptomycin.This helped explain why doctors in Europe had difficulties in fighting the bug that has killed 18 people and sickened nearly 2,000, BGI's major research arm in Shenzhen said on its website Saturday.This would help doctors choose right medicines for the treatment, it said.The researchers are developing a diagnostic kit which will be used to detect the bacteria and prevent the epidemic from spreading further.The Chinese researchers obtained DNA samples of the bacteria from collaborating scientists in Germany and fully sequenced its genome in three days this week.They announced on Thursday the E. Coli spreading through Europe was "a new strain of bacteria that is highly infectious and toxic".The 0104 strain of E. Coli was not previously involved in any E. Coli outbreaks. However, it has 93 percent sequence similarity with the EAEC 55989 E. Coli strain which was isolated in the Central African Republic and known to cause seriously diarrhea, BGI said.The source of the outbreak is unknown, but scientists say it is highly likely to have originated in contaminated vegetables or salad in Germany.