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SAN DIEGO (KGTV) — Infectious disease experts say it may take months before the first doses of a COVID-19 vaccine reach an important population: kids.Some doctors worry it may already be too late to get a vaccine authorized for younger kids before the start of the next school year because of the time it takes to recruit children and conduct a new round of clinical trials.“Our children under 12 years of age are almost certainly going into next school year without a vaccine option available for them,” said Dr. Evan Anderson, a pediatrician at Children’s Healthcare of Atlanta and associate professor at Emory University.Dr. Anderson said such a delay could further impact school reopenings and have resulting consequences on children’s mental health, among other concerns. He said the window is rapidly closing to get a vaccine authorized in time for children older than 12 unless more trials begin immediately.In October, Pfizer tested its vaccine candidate for the first time in 100 kids aged 12 to 15. Moderna is expected to begin testing in that age group in January, according to Dr. Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases. However, neither company has announced plans to begin testing their candidates in children under 12.That’s concerning to the American Academy of Pediatrics, which has been calling on vaccine-makers to include children in clinical trials since September. The AAP argues immunization is critical to stemming the pandemic.“We know that children can be infected with COVID-19 and can transmit it to others. To reduce the spread of this virus and control the pandemic as well as for their own safety, it’s crucial that children be included in the national vaccination program, and that vaccines are made available to children as soon as possible,” said Dr. Yvonne Maldonado, chair of the AAP Committee on Infectious Diseases, in another push last month.Although COVID-19 takes a more severe toll on older adults, children make up about 12 percent of the infections in the U.S. and recent studies have shown kids over 10 years old can transmit disease as efficiently as adults, the AAP noted.More than 1.3 million kids had been infected with COVID-19 as of Nov. 26.Experts say it’s important that drug companies test COVID-19 vaccines in children separately from adults.“Kids' immune systems are really different than adults. As any pediatrician will tell you, kids are not just small adults, their immune systems behave really differently,” said Dr. Christian Ramers of Family Health Centers of San Diego.Dr. Ramers said testing is needed to find the right vaccine dose for kids and see if there are any unexpected side effects.But there are challenging logistics in any pediatric trial. Since children’s immune systems change as they grow, vaccine-makers have to separate their trials into several age groups. That means more child volunteers are needed.“I mean it's more challenging, as an investigator myself for research, to enroll a kid into a study because you have to get permission [from parents],” said UC San Francisco infectious disease expert Dr. Peter Chin-Hong.Because parents have to sign off, experts say it can take much longer to enroll enough kids for a study.In a statement to ABC 10News, Pfizer said it is “working actively with regulators on a potential pediatric study plan.”“As we do with all vaccines which are initially studied in adult populations, we are following a careful, stepwise approach as we move down to younger age groups,” said Jerica Pitts, Pfizer’s director of global media relations.“Global regulatory agencies require evaluation of the candidate vaccine in pediatric populations. Moving below 12 years of age will require a new study and potentially a modified formulation or dosing schedule,” she added.Could a vaccine become mandatory at schools?Once a vaccine is approved for kids, a lot of parents are wondering if and when it might become mandatory at California schools.The California Department of Public Health told ABC 10News several things would need to be in place before it would consider making a vaccine mandatory at either schools or child care facilities.The vaccine would need to reviewed and approved by the FDA and recommended for use in children by the federal Advisory Committee on Immunization Practices. The state would also look for a recommendation by the American Academy of Pediatrics, and there would need to be "sufficient vaccine supply to enable access for all children."READ MORE: Will California make the COVID vaccine mandatory at schools? 4602
SAN DIEGO (KGTV) — It's a new season with new threads for the San Diego Padres.The Padres unveiled new home and away sets of uniforms sporting the team's classic brown colors during a fashion show-style event at Petco Park Saturday.Third baseman Manny Machado, first baseman Eric Hosmer, and shortstop Fernando Tatis Jr. were on hand to model the new look the Friars take into 2020. Two styles of the new uniforms featured a return to pinstripes, one on a white base reading "Padres" and the other on dark gray reading "San Diego." The third uniform was brown with gold "San Diego" across the chest and dark gray pants. 627
SAN DIEGO (KGTV) -- Maintenance crews were hard at work at UC San Diego Tuesday fortifying campus buildings ahead of the rainstorms expected this week, all while several dorms continued to dry out from the last one.Workers shored up roofs and deployed straw wattles and 200 sandbags near the Marshall Lower Apartments. The university said 12 to 15 dorms flooded last week during torrential rain.UC San Diego said drains near the apartment complex were overwhelmed by the water and debris.RELATED: UC San Diego students reeling from flooded dorms after storm“We conducted additional drain and area inspections of the Lower apartments in advance of the rain,” the university said in a message to residents. “[Housing, Dining and Hospitality] maintenance staff will be on standby to ensure that everything holds and storm drains remain clear.”The National Weather Service said a flash flood warning will be in effect Wednesday morning through Thursday evening in coastal areas and the inland valleys.The bulk of the rain is expected to hit Wednesday evening through Thursday morning. Rainfall totals through Friday could reach 1.5 to 2 inches in coastal areas and up to 3 inches in the San Diego County mountains, NWS meteorologist Miguel Miller said.UC San Diego maintenance crews were still trying to dry out some of the dorms that flooded with fans Tuesday, meaning some students have to contend with the hum of dehumidifiers while studying for midterms.RELATED: What you need to know about San Diego's Thanksgiving holiday storm“The dehumidifiers were kind of loud, but it was a constant sound so I got used to it,” said one student.Another student, Jason Rose, said not only did his apartment building flood, his car did too. The vehicle was parked in the Hopkins Parking Structure.“I was studying all night for a week, so I didn’t go to my car until four days after. When I opened my car door, it smelled terrible and when I looked inside it was just full of water,” he said.“It’s totalled probably,” he added.Rose said the university did offer to help with his insurance claim.Check 10News Pinpoint Weather conditionsStudents said maintenance crews have been quick to respond to issues, but with this week’s storms will be a test.“I’m pretty concerned,” said one student. “Especially because it seems like there’s not any long term changes right now. I know that takes longer to do, but I don’t think 10 sandbags are going to save all of our apartments.” 2466
SAN DIEGO (KGTV) — It has now been seven months since the pandemic began, and there are still a lot of questions about the best ways to treat patients with COVID-19.Researchers at UC San Diego are leading an effort to produce swift and reliable answers that could help doctors tailor treatments and hospitals plan bed space more efficiently.Doctors agree: the best way to fight any disease is to tailor the treatment for each individual based on their age, gender, race and other factors. But how does one doctor do that with a new disease like COVID-19, especially if their hospital has only seen a few hundred cases?“There might be some patterns you can get from 500 patients but there might be some others that you cannot,” said UCSD professor Dr. Lucila Ohno-Machado, chair of the Department of Biomedical Informatics.Dr. Ohno-Machado’s solution? Pool data.She’s leading the charge behind COVID19questions.org, a collaboration between 12 medical systems spanning more than 200 hospitals across the country.The collaboration includes several University of California health systems, the University of Texas Health Science Center at Houston, the University of Colorado Anschutz Medical Campus, and the largest organization in the cohort, the Veterans Affairs Healthcare System.“Each hospital is a little small to answer the questions. So by having it all together, we get the answers quicker,” said Ohno-Machado.They’re going after answers on how long patients with diabetes or cancer stay in the hospital, and whether COVID-19 is deadlier for smokers or non-smokers.Their findings revealed that men are much more likely to wind up on a ventilator than women.And they quantified just how much better we’ve gotten at treating COVID-19 over time.Since May 1, hospital stays among surviving patients have shrunk more than 10 days on average. That’s important for hospital managers planning and predicting bed space.“We decided to open this to the public and to our colleagues, and then we pick which answers have not been answered before and seem to be of most general interest,” Dr. Ohno-Machado explained.If this sounds like a straightforward approach, it’s not. Patient confidentiality laws make it hard for hospitals to share data and the information released by the CDC is limited.Maintaining patient confidentiality while sharing granular data is the most groundbreaking feature of the collaboration, called Reliable Response Data Discovery or known by its Star Wars-inspired acronym, R2D2.UCSD said R2D2 differs from other patient databases and registries because each health system maintains control of data rather than sharing it in a central repository. Through advanced computer techniques, each partner agency shares aggregated data, not patient-level information.The collaboration’s research is based on what’s called “observational data,” so Dr. Ohno-Machado said it’s not a replacement for a randomized, controlled clinical trial, which takes time. She noted their data reflects lessons on hospitalized patients, not everyone infected with the virus.But she said at a time when fast answers can save lives, COVID19questions.org could help. 3161
SAN DIEGO (KGTV) — It’s decision time for the San Diego Padres, who are trying to choose the right candidate to replace fired manager Andy Green.Widespread reports, confirmed by 10News, indicate the Padres have narrowed their search to two very different candidates.The first is 38-year-old Jayce Tingler, who has worked in a variety of coaching and front office roles with the Texas Rangers, but has no Major League managerial experience.RELATED: Padres' Yates wins Baseball Digest's top reliever awardThe second is 67-year-old Ron Washington, who managed the Texas Rangers to back-to-back World Series appearances in 2010 and 2011, before stepping down in 2014. He's currently the 3rd base coach for the Atlanta Braves.The Padres have previously stated a preference for an experienced manager, which could give Washington the edge. But the decision largely rests on the shoulders of general manager A.J. Preller, who is said to be high on Tingler’s ability to communicate with players in English and Spanish along with his understanding of baseball analytics.The timing of the decision remains unknown but both candidates were in San Diego this past week for second interviews with club officials.RELATED: Padres to unveil new 2020 uniforms in NovemberThe team fire Green days before the conclusion of the regular season. Green manned a 274-366 record during his four seasons with the team.Following Green's dismissal, Preller said "the biggest thing I know is we’re better than what we’ve shown," during a media conference. He added that he felt the team needed a "different voice, different direction" moving into the 2020 season."It's a big decision. You don't want to be sitting here in this spot again," Preller told media on hiring a new manager. "It'll be a good process. It'll be detailed." 1808