成都腿部血管炎好治疗医院(成都市中医血管炎医院) (今日更新中)

It’s hard to regard Ellie as a menace.When Greg Manteufel is frustrated or feeling down, she sits by him. At night, she sleeps under his covers. At dinner, she’s there next to him, knowing he’ll throw something her way. She belies the stereotype of the vicious pit bull.“We love her like she’s our daughter,” he said of the dog.And yet, Ellie may be the reason Manteufel nearly died.Gravely ill, he lost parts of his arms and legs, as well as the skin of his nose and part of his upper lip. The cause was capnocytophaga (cap-noh-seye-TOE’-fah-gah), a germ from Ellie’s mouth or from another dog he encountered.Capnocytophaga is commonly found in the saliva of cats and dogs and almost never leads to people getting sick, unless the person has a compromised immune system. But Manteufel was perfectly healthy. In fact, he doesn’t think he’d ever used his health insurance before he fell ill.The case is extremely rare and doctors at his hospital, Froedtert & the Medical College of Wisconsin, had no explanation for why he got so sick. But over the last 10 years there have been at least five other healthy people who have had severe reactions to the germ. A team of researchers connected with Harvard Medical School has developed a theory on why — a gene change in all the victims.And their finding means doctors can’t rule out the capnocytophaga bacteria could strike Manteufel and other victims again.___Greg Manteufel thought he was getting the flu in June of 2018. He had a fever, vomiting and diarrhea. But when he started getting confused, his family took him to the hospital.Doctors did blood cultures and found capnocytophaga, which caused sepsis, a severe blood infection that led to his blood pressure dropping and many of his organs shutting down.“Do what you have to,” he told the doctors.He had so much to live for — foremost, his wife of 16 years, Dawn, and 26-year-old son, Mike. He was just starting to get really good at his day job, painting houses. He cherished his Harley Davidson Electric Glide. He was in the middle of fixing up his ’66 El Camino. And of course there was Ellie, the pup.And so he persisted, through more than 20 surgeries, including amputations of his left and right arms just below the elbow, and legs through the middle of the knee.His wife and son stayed optimistic, because he was.“Greg said he didn’t come this far to lay down and let this beat him,” Dawn Manteufel said.He was out of the in-patient rehab unit in about two weeks, learning to move from his wheelchair to the bed, toilet and car. The usual stay is three to four weeks, said Dr. David Del Toro, medical director for the inpatient rehab unit at Froedtert.Manteufel made similar quick advances using his arm prosthetics and leg prosthetics.“He does not seem like any other patient I’ve met before,” Del Toro said. “He’s just, you know, full speed ahead.”Meanwhile, researchers at Brigham and Women’s Hospital in Boston, connected to Harvard Medical School, as well as Dana-Farber Cancer Institute and Beth Israel Deaconess Medical Center had been investigating cases like his.The team has done genetic testing on five otherwise healthy people who suffered capnocytophaga infections to see if they could find anything in common. They discovered all had a gene connected to the immune system that was working differently — a genetic variant.“It was a really thrilling moment,” said Elizabeth Fieg, a genetic counselor at Brigham and Women’s Hospital. “The stakes are so high with these cases and the patients have gone through so much.”They believe it makes those people more susceptible to developing severe medical problems from capnocytophaga. But they are also trying to determine if there are other risk factors.Of the five in the study, three survived with amputations and two did not. Fieg hopes their research can determine why some did not survive.She also hopes if their theory is confirmed, it will help diagnose cases faster, and perhaps save lives and limbs.That’s why Greg Manteufel jumped at the chance to take part when he was approached in August.Researchers need to gather more evidence, but hope to publish their study in the next year to 18 months.___Manteufel’s life now includes frequent occupational therapy appointments to perfect his use of arm prosthetics — the kind with metal moveable hooks at the end. He’s using a fork regularly and he’s now working on picking up the TV remote, opening doorknobs, cutting vegetables and doing the dishes.He’s using shortened leg prosthetics, called stubbies, to get his body conditioned to eventually use to full-sized ones. Those are expected to arrive any day.Plastic surgeons plan another surgery to perfect his nose. They’ve already moved skin from his forehead there. It looks oversized now, but it will eventually fit in with the rest of his face.He plans to get his car revamped so he can drive with prosthetics. He wants to get a special pole so he can go fishing again. He is even considering going back to work painting.He’s also become less quiet and a lot more outgoing. “Now everybody I see wants to hear something or talk to me. I tell them a 15-minute story about what happened. They probably want me to leave, you know,” he said, chuckling.Ellie’s often by his side.“She loves kids. She loves puppies. Other dogs,” Manteufel said.As harmless as she seems, she may have capnocytophaga germ.The results of Manteufel’s genetic tests are expected in three to four months. Fieg said people with the gene variant are at increased risk for recurrent capnocytophaga or other infections in the future.While Manteufel doesn’t like the sound of that, he said Ellie’s accidentally scratched him since he’s been home and even licked his mouth. He’s been fine.And even if he does have the gene variant, he said, it changes nothing.“We didn’t even bother testing her,” said Manteufel. “We weren’t going to get rid of her if it was her that caused it anyway.”“We just love her to death.” 5972

INDIANAPOLIS — President Donald Trump has ordered all flags to be flown at half-staff after a deadly mass shooting Friday in Virginia Beach. In a proclamation signed Saturday, Trump ordered the flags to be flown at half-staff until sunset on June 4. Authorities say 12 people were killed in the mass shooting Friday. You can read the full proclamation below: 371

It begins with a smiling teen boy, opening his locker to retrieve the "perfect" backpack that his mom bought him.It ends with a young girl, in tears, texting a goodbye to her mother as a door opens and foot steps approach.The 238

Jimmy Carter was the first U.S. president born in a hospital. Today, he marks a new milestone as the oldest living former president ever.At 94 years and 172 days old, Carter has passed the previous record held by the late 234

In the nation’s capital, when it comes to immigration, much of the focus is often on the southern border and undocumented migrants. This month, though, it’s immigrants that have come to the U.S. legally who are about to face new challenges, as they try to become permanent residents or U.S. citizens.Public assistance, like Section 8 housing vouchers or food stamps, could play a big role in the fight over immigration.It is called the “public charge” rule and it is not new; it’s been on the books since the late 1800s. What is new, however, is what defines a public charge.Back in 1882, when immigrants arrived in the U.S., they had to prove they had cash and enough money to get where they were going, once they landed.Fast forward to 1996: that’s when the government decided other factors should be included as part of a green card application – like a person’s finances, health, age, education – and whether a sponsor, such as a family member who is a citizen or already has a green card, could financially vouch for you.Now, the rule will change again. Immigration officials will be able to deny a green card if they think some will “likely” end up needing public assistance, like welfare, food stamps or Medicaid.If that person needed such help in the past, it could count against them. That is placing greater scrutiny on the 400,000 people each year, who apply for to become permanent residents in the U.S.The Trump Administration argues the change is needed so that public assistance is safe-guarded for U.S citizens and residents who need it.“The benefit to taxpayers is a long-term benefit of seeking to ensure that our immigration system is bringing people to join us as American citizens, as legal permanent residents first, who can stand on their own two feet, who will not be reliant on the welfare system,” said Ken Cuccinelli, acting director of the United States Citizenship and Immigration Services, in making the announcement in August. Yet, some who work with the immigration system disagree. Aaron Hall is an immigration attorney in Denver.“Every change that’s happened over the last two years has been aimed at making the immigration process more burdensome, more difficult,” Hall said. Hall added that not only is the definition of a “public charge” changing, so is the green card application itself.“For the first time ever, they’re asking applicants to provide a credit score,” he said. “People who have not had immigration status prior or who have spent time living in a foreign country are not going to have a credit score. So, they have negative factor against them, even before they get started with their application.”The revised “public charge” rule is set to take effect on Oct. 15, but it is already being challenged by multiple states in court. A could injunction could delay it as the lawsuits make their way through the courts, a process that could potentially take years. 2922

来源：资阳报