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WASHINGTON, Nov. 24 (Xinhua) -- An inexpensive drug that treats Type 2 diabetes has been shown to prevent a number of natural and man-made chemicals from stimulating the growth of breast cancer cells, according to a newly published study by a Michigan State University researcher. The research, led by pediatrics professor James Trosko and colleagues from South Korea's Seoul National University, provides biological evidence for previously reported epidemiological surveys that long-term use of the drug metformin for Type 2 diabetes reduces the risk of diabetes-associated cancers, such as breast cancers.The research appeared online this week in PLoS One.For the study, Trosko and colleagues focused on the concept that cancers originate from adult human stem cells and that there are many natural and man-made chemicals that enhance the growth of breast cancer cells. Using culture dishes, they grew miniature human breast tumors, or mammospheres, that activated a certain stem cell gene. Then the mammospheres were exposed to natural estrogen -- a known growth factor and potential breast tumor promoter -- and man-made chemicals that are known to promote tumors or disrupt the endocrine system.The team found that estrogen and the chemicals caused the mammospheres to increase in numbers and size. However, with metformin added, the numbers and size of the mammospheres were dramatically reduced. While each of the chemicals enhanced growth by different means, metformin seemed to be able to inhibit their stimulated growth in all cases."While future studies are needed to understand the exact mechanism by which metformin works to reduce the growth of breast cancers, this study reveals the need to determine if the drug might be used as a preventive drug and for individuals who have no indication of any existing cancers," Trosko said.

PHNOM PENH, Oct. 3 (Xinhua) -- Cambodia reported on Monday that some 54 Cambodian children had been killed by dengue fever in the first nine months of this year, compared to 37 kids dying of the disease in the whole year of 2010.From January to September this year, some 12,392 cases of dengue fever had been reported with 54 children killed by the disease. The whole year 2010 reported only 5,497 cases, Ngan Chantha, director of dengue control at the Ministry of Health, said on Monday."This year's rainy season has been plagued by floods, leading to more cases of the disease," he said. "I would like to appeal to parents to let their children sleep under mosquito nets and if their kids have any symptom that is suspicious of the disease, they should urgently send them for medical attention."Dengue is caused by mosquitoes. The disease causes an acute illness of sudden onset that usually follows symptoms such as headache, fever, exhaustion, severe muscle and joint pain, swollen glands and rash.In Cambodia, the outbreak of dengue fever usually begins at the onset of the rainy season from May to October. 

BEIJING, Jan. 17 (Xinhuanet) -- India has reported the first case of "totally drug-resistant tuberculosis," a long-feared and virtually untreatable form of the killer lung disease.Similar highly resistant cases have been noted before. In 2003, two Italian women died and there were 15 cases reported from Iran in 2009. That same year, The Associated Press reported on a case of a Peruvian teenager who was infected at home but diagnosed while visiting Florida.Such kind of TB has mostly been limited to impoverished areas, and has not spread widely. But experts believe there could be many undocumented cases.No one expects the Indian TB strains to rapidly spread elsewhere.The airborne disease is mainly transmitted through close personal contact and isn't nearly as contagious as the flu. Indeed, most of the cases of this kind of TB were not from person-to-person infection but were mutations that occurred in poorly treated patients.The Indian hospital that saw the initial cases tested a dozen medicines and none of them worked. A TB expert at the U.S. Centers for Disease Control and Prevention said they do appear to be totally resistant to available drugs."It is concerning," said Dr. Kenneth Castro, director of the CDC's Division of Tuberculosis Elimination. "Anytime we see something like this, we better get on top of it before it becomes a more widespread problem."Ordinary TB is easily cured by taking antibiotics for six to nine months. However, if that treatment is interrupted or the dose is cut down, the stubborn bacteria battle back and mutate into a tougher strain that can no longer be killed by standard drugs. The disease becomes harder and more expensive to treat.Tuberculosis is an age-old scourge that lies dormant in an estimated one in three people. About 10 percent of those people eventually develop active TB, which kills roughly 2 million a year, according to WHO. Each victim infects an average of 10 to 15 others every year, typically through sneezing or coughing.If a TB case is found to be resistant to the two most powerful anti-TB drugs, the patient is classified as having multi-drug-resistant TB (MDR). An even worse classification of TB — one the WHO accepts — is extensively drug-resistant TB (XDR), a form of the disease that was first reported in 2006 and is virtually resistant to all drugs.About 20 percent of the world's multi-drug-resistant cases were found in India, which is home to a quarter of all types of tuberculosis cases worldwide.

BEIJING, Jan. 1 (Xinhua) -- President Hu Jintao, along with other Chinese leaders, celebrated the New Year with political advisors Sunday morning in Beijing and delivered an important speech.Hu and the other members of the Standing Committee of the Political Bureau of the Communist Party of China (CPC) Central Committee Wu Bangguo, Wen Jiabao, Jia Qinglin, Li Changchun, Xi Jinping, Li Keqiang, He Guoqiang and Zhou Yongkang attended a tea party held by the National Committee of the Chinese People's Political Consultative Conference (CPPCC).

BEIJING, Jan. 6 (Xinhua) -- Surveillance data on the size and frequency of earthquakes in Antarctica collected by China's Great Wall Station show that the continent is not earthquake-free, a Chinese seismic expert said Thursday."China's newly-built seismic observatory in Great Wall Station has documented a hundred-odd earthquakes occurring in the region over the past year," said Chang Lijun, a member of China's 28th Antarctic expedition team.The discovery challenges the prevailing notion that the Antarctic has no earthquakes, as many earthquakes have gone undetected due to lack of seismological observation in the region.However, thanks to technological advances, scientists have discovered that the continent is still subject to some minor tremors.Chang, also an associate researcher at China Earthquake Administration's Geophysics Institute, said last year's earthquakes ranged in magnitude from 0.5 to 4, scales which are usually undetectable to common people.The tectonic movements of Antarctica, which sits on two plates that pulled away from each other in the northern Ross Sea between 28 and 40 million years ago, but later converged, fascinate geologists worldwide.At the end of 2010, Chinese scientists set up a new broadband seismic observatory in Great Wall Station, greatly increasing China's ability to measure tremors and tectonic movements on the continent.

来源：资阳报