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SAN DIEGO (KGTV) -- Barrio Logan businesses are moving outdoors on Saturday in hopes of bringing in some revenue. The businesses are hosting the first Walk the Block, which will include outdoor dining, live music and shopping. The business were struggling because of pandemic closures and they tell ABC 10News that they decided to get permits to be able to serve and sell to customers outdoors. All social distancing and mask rules will apply. Walk the Block will go on from 12 p.m. to 7 p.m. from Chicano Park to 26th Street. 536

SAN DIEGO (KGTV) - Could you feed yourself on about per day? The San Diego Hunger Coalition is encouraging San Diegans to take part in the annual CalFresh Challenge to raise awareness about food insecurity. CalFresh public assistance allots .07 daily in food benefits, according to SDHC. The system, known nationally as SNAP, helps those in need but it is insufficient for helping people meet basic needs, SDHC says. During the CalFresh Challenge, participants must spend no more than .35 for five days on all meals, drinks, and snacks. During the week, participants must not accept free food. San Diego Hunger Coalition wants participants to post about the experience on social media with the hashtag #CalFreshChallenge. Participants are also asked to donate to SDHC. 784

SAN DIEGO (KGTV) -- As Hurricane Maria barrels past Puerto Rico and toward the Dominican Republic, one San Diegan is finally home from a different storm.  167

SAN DIEGO (KGTV) — Around San Diego, there are plenty of chances to treat dad to a special freebie or event for Father's Day.San Diego's local Father's Day events celebrate the day for dads with some BBQ fun, with live music and plenty of delicious food.A handful of local eateries will also toss in a freebie along with the meal on Father's Day for dads.Here are a few specials to treat dad to this Father's Day:FoodRuth's Chris Steakhouse: Dads get a gift card if they dine at Ruth's Chris on Father's Day. Also, when buying 0 worth of gift cards, get a bonus gift card.Fogo de Ch?o Brazilian Steakhouse: Dads who eat at Fogo de Ch?o on Father's Day get a complimentary dining card for one full Churrasco lunch, dinner or Sunday brunch on his next visit.Mimi's Cafe: Dads get a free appetizer with purchase of an entree on Father's Day.Wienerschnitzel: Dads get a free old fashioned sundae at Wienerschnitzel restaurants on Father's Day.EventsBelmont Father's Day Fest and Car Show: Check out nearly 200 classic and modern cars, live music, a Father's Day brunch and cornhole tournament, and free activities during Belmont Park's Father's Day celebration.Maritime Museum Father's Day Sail: Sail aboard the Maritime Museum's tall ships, like the "Californian" or "San Salvador," on Father's Day weekend for a three-hour trip around San Diego Bay. Lunch with a drink will be included on the journey.Father's Day BBQ at 10 Barrel Brewing: Celebrate dad at 10 Barrel Brewing's Father's Day BBQ, complete with shuffleboard, games, beer, and a BBQ feast for from Chef Tommy Fraioli. Father's Day Concert and BBQ: The Hotel Del Coronado will hold their annual Father's Day Concert & BBQ to support the Gary Sinise Foundation. The event kicks off with a skydiving show followed by food, drinks, and live music from Gary Sinise & The Lt. Dan Band.Father's Day cruises: Take dad on a Hornblower Father's Day cruise for a two-hour tour of San Diego Bay, a special Father's Day brunch buffet, and live music. Dad also gets a free pint glass.Classic Car Show: Check out Belching Beaver Brewery's 6th annual Classic Car Show in Vista for a day of cars and brews. 2181

SAN DIEGO (KGTV) — As the world waits for a vaccine against the coronavirus, two San Diego biotechs are teaming up to develop a nasal spray using designer antibodies cloned from COVID-19 survivors.About 70 companies worldwide are working on therapies for COVID-19 using cloned antibodies, according to an estimate by the International AIDS Vaccine Initiative. A few of these treatments, known officially as monoclonal antibody therapies, have advanced to clinical trials.Most require an injection, but San Diego-based Diomics and its partner Active Motif, based in Carlsbad, are developing a once-a-day spray that could be easily self-administered.Early research suggests the coronavirus primarily enters the body through the nose. The spray, called Dioguard, is designed to coat the lining of the nasal cavity with cloned antibodies that are held in place for 24 hours or more using a proprietary polymer material developed by Diomics.Diomics CEO Anthony Zolezzi said he believes the spray “holds the key to allowing many aspects of life to resume until the day comes when there’s an effective vaccine in widespread use.”Diomics is also developing two tests for COVID-19 antibodies using its polymer beads, including a device that looks like a nicotine patch that is designed to monitor for infections for a week or more.RELATED: How a dot on your forearm could be the future sign of COVID immunityActive Motif is providing the cloned antibodies for the nasal spray. With a lab in Shanghai and other relationships in China, the Carlsbad company was able to clone antibodies from 11 Chinese survivors in February, before the World Health Organization declared a pandemic.When the company started the cloning project, they thought the virus would probably disappear in three to six months, said Active Motif CEO Ted DeFrank. “Then people started realizing, no this is going to be with us for a while.”The plasma from the 11 Chinese patients contained thousands of antibodies, and scientists with Active Motif set about selecting the one that was most effective, dubbed 414-1. The company says it can neutralize SARS-CoV-2 virus particles with 98 percent effectiveness.Monoclonal antibodies have some similarities to convalescent plasma, which is a complex cocktail of antibodies and other immune molecules drawn from the blood of recovered patients. One of the key differences is that cloned antibodies can be mass produced in a lab.Cloned antibodies have been used in treatments for more than 30 years, primarily for cancer. One such treatment famously helped former U.S. President Jimmy Carter beat melanoma.But of the more than 100 monoclonal antibody therapies licensed for use, only seven are for communicable diseases, according to IAVI.Historically, the treatments have been expensive and difficult to produce, but Diomics said it’s targeting a price of about a spray for Dioguard, roughly per bottle.“We do not want to have huge profits from a pandemic, that’s just wrong,” Zolezzi said. “We’re going to price this as effectively as we can for the masses. We want to get this out to the masses.”Animal testing is about to begin and the companies said they hope to progress to human trials soon. Their goal is to release the spray in early 2021, when a vaccine may be on the market but not yet widely available.If the spray works, it could be adapted to other viruses to help fight future pandemics, Zolezzi said."That’s our real goal," Zolezzi said. "That we never get caught flat-footed like this time." 3526