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The trial points to the retinas in a patient’s eyes as possible clues to diagnosing Alzheimer's using equipment that’s already standard in many optometry and opthalmology offices. Doctors are hopeful the new detection could mean diagnosing the disease up to 20 years before symptoms start. The clinical trials are crucial for families like the Lees. Kristine Lee watched as Alzheimer’s slowly stole her grandma’s memory, slipping away one phone call at a time. “We’d call and say ‘Hi Grandma! We love you hope you’re doing well.’ My aunt would say, ‘She heard your voice. She smiled,’ but eventually that progressed,” Lee said.Lee lost her grandma by the time she turned 18, but her death soon shaped her entire career when she joined the Alzheimer’s Association and started heading up races in an effort to raise money in search for a cure. “I was like this is where I belong,” Lee said with a smile.Dr. Stuart Sinoff, a neurology physician at BayCare knows that pain too. “I lost my mother to Alzheimer's in February,” he said softly. Coincidentally, her diagnosis happened years after Sinoff began researching new ways to detect Alzheimer’s . “My mom was not clearly an Alzheimer’s patient at that time so that kind of happened to come along because we’re all touched by this condition,” Sinoff explained.Now, Sinoff and doctors from Butler Hospital in Providence, Rhode Island, are about to launch a million clinical trial to study retinas to detect Alzheimer’s years before memory loss begins. “When you leave your keys, when you’re wondering what your shopping list was, is it really just the relatively expected mild change in aging or do you have an important neurodegenerative disease that might be the beginning of something really disastrous? This research will pave the way for patients to find out sooner,” Sinoff added. The test is not only faster but costs a fraction of standard diagnosis. The retina scan is estimated to cost around , compared to ,500 for the average PET scan. 2003

"The same energy that went into finding those old tweets could be the same energy put in to finding the response to the questions that have been asked years after years after years. We feed the internet trolls and reward them. I'm not going to do it man. I'm going to be me. I'm going to stand my ground.

The woman described Aghdam as a very reserved person who often walked with her head down and was very shy -- a stark contrast to the flamboyant personality she presented on her YouTube channel. 193

The rush now is to move the legislation as quickly as possible. Lawmakers have until Friday at midnight to pass the bill before the government runs out of money. The House is expected to vote on the plan later this week -- likely Thursday, according to House Deputy Whip Patrick McHenry -- but the main obstacle will be whether the Senate can move quickly enough to avert a shutdown given its rules. If one lawmaker objects, it could force Senate leaders to run out the clock and even face a temporary shutdown into the weekend.A Senate GOP aide says if the House passes the bill Thursday, the Senate could take it up later that day. But passage probably wouldn't take place until at least Friday. The aide didn't know of any senators wanting to put up procedural hurdles that could slow walk the bill past the Friday funding deadline.House Republicans leaders are discussing the possibility of waiving the so-called "three-day rule" and holding a vote on the package as soon as Thursday, according to one aide, though nothing has been decided yet.Democratic and Republican leaders huddled Wednesday morning to put the finishing touches on the bill."We hope we'll be ready to go in two hours," Senate Minority Leader Chuck Schumer said Wednesday morning following the meeting between leaders in Speaker Paul Ryan's office.Sen. Rand Paul, a Republican from Kentucky who forced a brief shutdown in February because of his opposition to a spending bill, said he has not made a decision about whether he would hold up this proposal."I haven't made a decision yet about whether or not I'll consent to time agreements, " he told reporters Tuesday.The release of the legislation was delayed as negotiators spent the early part of the week haggling over controversial policy riders on immigration, infrastructure and health care. What was expected to be a bill released Monday dragged into Wednesday. 1892

The Shape of Water and "Three Billboards Outside Ebbing, Missouri" -- two very different love stories of sorts -- are somewhat favored. But Jordan Peele's political thriller "Get Out," Greta Gerwig's coming-of-age film "Lady Bird," and the war drama "Dunkirk" are also seen as contenders. 338