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SAN DIEGO (KGTV) — Independent reviews by the FDA show the COVID-19 vaccines by Pfizer and Moderna have similar levels of safety and efficacy, although there are early indications of potential differences.Both vaccines rely on the same basic approach: jumpstarting the immune system with messenger RNA. The FDA confirmed their overall efficacy is essentially identical; 95 percent for Pfizer and 94.1 percent for Moderna.However, signals in the data suggest Moderna’s vaccine may better protect against severe cases of COVID-19, while Pfizer’s vaccine may work better in adults over 65. But experts warned those differences may just be statistical illusions.In Moderna’s study of 30,000 volunteers, 30 people got severe cases of COVID-19. All 30 of those cases were in the placebo group, suggesting the vaccine offers powerful protection against the most serious symptoms.In Pfizer’s trial of 44,000 volunteers, one vaccinated person got a severe case compared to 10 people in the placebo group.“We still need more data,” said Dr. Abisola Olulade of Sharp Rees-Stealy. “It's not a reason to recommend one versus the other.”In adults over 65, the efficacy of Moderna’s vaccine dipped slightly to 86.4 percent. Pfizer’s vaccine was 92.9 percent effective in people aged 65 to 74 and 100 percent effective in individuals 75 and up.“When I think people in the community look at that number, they might say, ‘Oh, that Moderna vaccine probably isn't as good for the older population compared to the Pfizer vaccine.’ But as a clinician looking at numbers, they're both amazing,” said UC San Francisco infectious disease expert Dr. Peter Chin-Hong.FDA scientists found both vaccines are safe but short-term side effects are common, especially with Moderna’s drug. Both vaccines are administered in two doses. The table below lists the percentage of vaccinated volunteers who reported a side effect after either dose, although side effects were most common after the second injection.Side effect Moderna PfizerFatigue 68.5% 62.9%Headache 63.0% 55.1%Muscle pain59.6%38.3%Joint pain44.8%23.6%Chills43.4%31.9%Fever14.8%14.2%Typically the symptoms went away in one day.“Just because a vaccine has side effects doesn’t mean it’s not safe,” said Dr. Olulade. “We know that side effects happen actually because your immune system is working and waking up. It's actually a positive thing.”The slight difference in side effects could be because of differences in the way researchers polled volunteers, or it could be something with the architecture of the vaccines, experts said.The companies use different tiny bubbles of fat to enclose the messenger RNA. Moderna’s bubble is a little stronger and more stable so it doesn’t need to be stored at sub-arctic temperatures.“It could be that [Moderna’s] elicits a little more inflammation than the other,” Dr. Chin-Hong said.Having slightly more side effects could be a sign that Moderna’s vaccine prompts a stronger immune response that might lead to longer-lasting immunity, but the durability of either vaccine remains one of the most pressing unanswered questions.The biggest difference may be where the vaccines are deployed. Since Pfizer's vaccine needs to be stored at such cold temperatures, experts said Moderna's vaccine may be prioritized for rural hospitals and community health centers that lack ultra-cold storage units. 3370
SAN DIEGO (KGTV) -- Just days before masses of people are expected to descend on Del Mar for the San Diego County Fair, a busy road has reopened following a bluff collapse. City crews completed a retaining wall and reopened Jimmy Durante Boulevard Wednesday afternoon. The road wasn't originally expected to reopen until June 4, several days after the fair opens on May 31. RELATED: What to know for the San Diego County FairThe northbound lanes of Jimmy Durante Boulevard closed in late April after part of a bluff collapsed. The cost of cleanup and stabilizing the cliff is expected to cost million. At a meeting in May, the city council voted to declare a local emergency, allowing the city to qualify for federal emergency funds. 745
SAN DIEGO (KGTV) -- It all started when La Jolla Shores resident, Penne Horn, had a birthday coming up."It started as a joke. My son asked what I wanted for my birthday and without any thought the words flew out of my mouth 'I want an ice cream maker,'" Horn said. The rest you could say is history.Since the day she received her wishlist item, she like many of us, spent time indoors with her new addition. "I started making ice cream. I just had too much of it and thought there's gotta be something I can do with this," Horn described. So she began to give it away to neighbors. It was so good that nearby residents with a sweet tooth wanted more and insisted on paying her, when a light a bulb went off. "I was hearing stories of families who got dogs in beginning of COVID, then lost their job and couldn't feed family let alone their dogs. I thought I will make the ice cream and ask people for donations. They'll donate and I'll buy dog food, and take it down to St. James church where they'll distribute it." Then new ideas kept getting added to the mix."One lady came to me and said I'll donate whatever if you make an ice cream named after my dog." Then, Twoee's Howling Good Ice Cream was born, named after her own sweet furry companion. "I draw all these different characters of dogs and name the ice cream after their dog."Horn's a former member of the Scripps and Humane Society boards, and she's always given back to the community. "It's part of my life, it's part of who I am."This time around, her community service was something new, a bit more sweet and born out of a pandemic. "There's a little silver lining if you look for it, I never would've started this if it hadn't been for the pandemic. There's good in everything." So far, Horn had donated over 400 pounds of dog food to local churches and the San Diego food bank. Click here more information on Twoee's Howling Good Ice Cream. 1915
SAN DIEGO (KGTV) — Light scattered showers fell throughout the day from Mission Valley to Carmel Valley.While Sunday's rainfall marked the first fall rain for the region, Alex Tardy with the National Weather Service said that rain will disappear by Monday. “We're looking at conditions that are bone dry, record dry. It’s never been this dry before and just a little bit of rain like this, while it's nice and we won’t have any fires [Sunday], once the dry air starts blowing through on Monday and continues into Tuesday, it's not going to make much of a difference,” Tardy said.RELATED: In-depth: Why La Ni?a could make wildfire season worseTardy said that San Diego may go long stretches without rainfall this season as we move into a dry La Ni?a winter. However, when the rain eventually comes, it could come in sporadic heavy storms. Tardy also added that the conditions will have fire crews on high alert for weeks. “It also means a delay in the start of our winter so we could be in for a very long fall period where we mostly see dry conditions,” Tardy says. “What that means for us is that fire danger [could be] continuing into the fall and well into the early winter.” 1186
SAN DIEGO (KGTV) — Jayce Tingler doesn't plan to be a homebody in the San Diego Padres clubhouse."I want to be shagging in the outfield ... If you're out being active, more organic natural moments will arrive," Tingler told reporters, saying that he doesn't plan to sit in his office often.The Padres introduced the former Texas Rangers coach to the media at Petco Park Thursday. In front of a backdrop of brown and gold, general manager A.J. Preller spoke on Tingler's experience and confidence in him managing the team starting in 2020. Notably, Preller said he was looking for someone players would "run though a wall for" in his search.RELATED: San Diego Padres to unveil new 2020 uniforms in NovemberBefore Tingler arrived in San Diego to don number 32, he worked with the Rangers has a field coordinator and interim bench coach. Preller hailed Tingler's experience in player development for the organization, and bilingual and communication skills. The duo worked together while Preller was a scout and assistant general manager in Texas. Preller said Thursday that Tingler had showed him that he's "comfortable being uncomfortable" from his success as a young manager in the Dominican Republic.But the big question for many outside of Preller's is Tingler's experience. He becomes the Padres 21st manager in franchise history and the team's sixth-straight skipper without prior MLB managerial experience."Look, I'm going to make mistakes. My guess is at some point the players are going to make mistakes. So we have some common ground," Tingler said. "I hope to learn quick. I hope to have people around from various areas of expertise."Part of the expected change between 2019 to 2020 will include other coaching positions. Tingler says he's looking to surround himself with a staff that pushes players."We're in that process. We're meeting with people. The bottom line, can you build relationships and can you impact players, can you push them and make them better," Tingler said.Tingler walks into a club that has under delivered for the last decade. Last season marked the Padres' ninth-straight losing season. Former manager Andy Green didn't fair better, posting a .428 win percentage during his four seasons with the team.The last time the team finished above .500 was in 2010, under then-manager Bud Black.To that, Tingler says he's confident in the current squad of players and looks forward to his new staff forming those all important relationships to impact young players — hopefully producing a winning season."We've got a lot of players with huge upside ... I think they shared that kind of undying passion to win here in San Diego," Tingler said. 2676