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KANSAS CITY, Mo. — After nobody won the most recent Mega Millions drawing, the jackpot prize for Tuesday is expected to approach record territory.No ticket sold for Friday’s drawing matched all five numbers plus the Mega Ball, so the jackpot will reach an estimated 4 million (2.6 million cash) on Tuesday.The Mega Millions jackpot record is a 6 million prize on March 30, 2012.The jackpot has been growing since July 24, when a California office pool of 11 people won a 3 million prize, according to a Mega Millions statement.That was the largest prize ever won on a single ticket.“It’s so exciting for our players, and all of us, to see the Mega Millions jackpot getting so close to an all-time record level,” Lead Director of the Mega Millions Consortium and Director of Maryland Lottery and Gaming Gordon Medenica said. “With a little luck, we may still break that record by Tuesday”The Powerball jackpot Saturday night was an estimated 4 million, a sizable sum in its own right.“Jackpot fever is definitely sweeping the country,” Medenica said. 1072
LA JOLLA, Calif. (KGTV) - A researcher at UC San Diego just got a million grant to further his work into nanosponge therapy.Liangfang Zhang, a professor of nanoengineering and bioengineering, has been working on creating macrophage cellular nanosponges, tiny particles covered in white blood cell membranes, to treat sepsis and other diseases."They can be used to bind to the virus and neutralize the virus," Zhang says. "So now the virus would lose the ability to infect the host cells."The nanosponges act as decoys, tricking a disease or virus into binding with them instead of with human cells. While the initial aim is to treat sepsis, Zhang says it has applications to other deadly diseases, including COVID-19."The formulation that we're developing for treatment of Sepsis is the same formulation that you will use with COVID-19," he says.The grant comes from CARB-X, a Boston-based medical philanthropy that specializes in funding research into antibacterial treatments. Zhang says the money will be used for his company, Cellics Therapeutics, to further advance the research into clinical trials, FDA approval, and production of the nanosponge therapy.Steve Chen, president and chief medical officer of Cellics Therapeutics, says he's hopeful they can advance the nanosponges into human trials within two years."We're essentially looking at how this platform can treat not just infectious disease or future pandemics, but you could actually have a lot of applications in any type of autoimmune diseases or any type of inflammatory diseases," says Chen.In an early study published this year, Zhang's research showed the nanosponges were around 90% effective at blocking infections from taking hold.RELATED: UC San Diego researchers testing nanosponges to fight COVID-19Chen says the research and trial period may take too long for the nanosponges to be used during the current coronavirus pandemic. But he's hopeful it will help make the next outbreak less severe."My sincere desire is that we are not going to need this for COVID-19. But I think this does position us very well for any potential future kind of viral outbreak," says Chen.Cellics is also working on a Red Blood Cell version of their nanosponges, which may be ready for human trials within a year. 2283

Kentucky Speaker of the House Jeff Hoover resigned from his position Sunday amid sexual harassment allegations, saying he had made "mistakes."Hoover, who The Courier-Journal newspaper in Louisville reported had secretly settled a sexual harassment allegation by a woman on his legislative staff, did not resign as a state representative, however, and has denied all allegations."I did make mistakes, in that I engaged in inappropriate text messages," the Republican lawmaker said at a press conference announcing his decision. "I engaged in banter that was consensual, yet make no mistake, it was wrong on my part to do that. And for that I am truly sorry."The Courier-Journal was the first to report Hoover's settlement last week, citing sources with direct knowledge of the matter. The settlement involved three other Republican state representatives and Hoover's chief of staff, the newspaper reported.Hoover and his accuser, whom the Courier-Journal has not identified because she says she was sexually harassed, declined to comment, as did a lawyer for the woman, the newspaper said.Hoover asked for the public's forgiveness in a tearful statement on Sunday, saying, "To say that the past few weeks and days have been trying and difficult for me and my family would be an understatement."Kentucky's House speaker pro tempore, Republican David Osborne, said in a statement that he will be assuming operational control of the chamber as acting speaker.Hoover's resignation comes a day after Kentucky Gov. Matt Bevin, also a Republican, called for "the immediate resignation of every individual who has settled a sexual harassment case, who is party to trying to hide this type of behavior."In a press conference Saturday, Bevin drew a "clear line in the sand for every elected official in Kentucky. These actions that have been alleged, not denied, and increasingly corroborated, and that are increasing in specificity and in number, were not isolated to a single person, or a single event, but involved multiple events and multiple people.""They know who they are, some have been named," Bevin said. "I would simply say this: For the sake of themselves, for the sake of their families and for the sake of Kentucky, they should resign. Period. The people of Kentucky deserve better than the type of shenanigans that have gone on for far too long in this town.""I expect the immediate resignation of everyone named," Bevin concluded.Hours after Bevin's speech, Hoover issued a statement that stopped short of confirming the Courier-Journal report."I am disappointed that our Governor in his press conference Saturday afternoon would call not only for my resignation but the resignation of other individuals who have no involvement in this matter," he said. "The governor has yet to ask our side of the story. He and I have not spoken since the story broke, and I did not receive a courtesy call from him before his grandstanding today. Instead, he has accepted as fact only, one side of the story.""In effect, the governor seeks to be judge, jury, and executioner without hearing the evidence," Hoover said, adding then that he had no plans to resign, and was "more resolved than ever to continue my work as speaker thru the 2018 session." 3264
Johnny Nash, a singer and songwriter best known for performing “I Can See Clearly Now,” has died at the age of 80, his family confirmed to NBC News.NBC News reported that Nash’s health has declined in recent months, but family did not state a cause of death.“I Can See Clearly Now” became Nash’s only No. 1 hit in 1972. Nash also had a top 10 hit in 1968 with “Hold Me Tight.”Nash achieved success at a young age, releasing three studio albums before his 20th birthday with Paramount. Besides performing pop music, he was known to be one of the few non-Jamaican artists to perform Reggae-genre music in the country. He collaborated with famed Reggae performer Bob Marley, and released a cover of Marley’s hit “Stir it Up.” 730
Jared Kushner told a software developer who worked at his newspaper, the New York Observer, to delete several "critical" stories in 2012, according to Austin Smith, the developer who said he "complied."Smith now has regrets about his involvement.Kushner was seeking to erase Observer stories that were "critical of his commercial real estate colleagues," Smith said in a Hacker News message board post.Back then, Kushner was the publisher of the Observer. Now he is a senior adviser to President Donald Trump.Smith said he was inspired to speak out by a recent Hacker News discussion about unethical behavior, plus the president's usage of extreme "enemy of the people" rhetoric to attack journalists."I didn't know any better then, but I do now," Smith said in a series of tweets on Monday.He said he is sorry for deleting stories by Observer staff members.BuzzFeed highlighted the deletions on Monday. A "handful of articles" were affected. The White House press office did not respond to requests for comment.According to emails seen by BuzzFeed's Steven Perlberg, Kushner went around the paper's editors "to mandate the removal of a handful of articles from the website."BuzzFeed noted that "the secret removal of stories due to outside pressure is widely regarded as an unethical practice in journalism."The editor at the time, Elizabeth Spiers, said on Twitter that she found out about this action "a few months ago." Her reaction: "I don't have enough choice expletives describe my feelings about that."How could Kushner pull this off without the newsroom knowing?"When you publish some 50 odd stories a week, you don't notice two or three missing here and there weeks after fact," Spiers told CNNMoney."We also had a couple of site redesigns and site search was abysmal," she added. "So if you didn't immediately find something in search there were more likely (at the time) explanations."Spiers has been critical of Kushner and other Trump White House officials.Kushner resigned from the Observer when he joined the Trump administration in January 2017. He transferred the paper into a family trust. 2116
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