成都得了脉管炎怎么治疗(成都得了动脉硬化怎样办) (今日更新中)

President Donald Trump’s physical Dr. Sean Conley confirmed Friday that the president is taking an experimental antibody treatment to help him fight the coronavirus following his diagnosis this morning.Dr. Conley said Friday afternoon that Trump is "fatigued."Trump is taking the Regeneron antibody cocktail, which is currently in a clinical trial. Conley said that Trump has been treated with a single 8 gram dose, which Conley said was infused "without incident."Trump is also said to be taking Vitamin D, zinc, famotidine, melatonin and daily aspirin. The Regeneron trial has only been tried on 275 patients as of this week, but the company said earlier this week that it has showed promising results.Regeneron confirmed that Trump was given the treatment under a "compassionate use request.""In the USA, this type of compassionate use program is also known as an Expanded Access Program (EAP) and is intended for patients with serious or life-threatening conditions, who do not have any viable or available treatment options, and are unable to participate in ongoing clinical trials," Regeneron said in a statement. The plan is to enroll 2,000 patients in early studies of the treatment."After months of incredibly hard work by our talented team, we are extremely gratified to see that Regeneron's antibody cocktail REGN-COV2 rapidly reduced viral load and associated symptoms in infected COVID-19 patients," said George D. Yancopoulos, M.D., Ph.D., President and Chief Scientific Officer of Regeneron. "The greatest treatment benefit was in patients who had not mounted their own effective immune response, suggesting that REGN-COV2 could provide a therapeutic substitute for the naturally-occurring immune response. These patients were less likely to clear the virus on their own, and were at greater risk for prolonged symptoms.The treatment is a combination of two monoclonal and was designed specifically to block infectivity of SARS-CoV-2, the virus that causes COVID-19, the company said.“The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus's spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.” Regeneron said in a statement. “Preclinical studies have shown that REGN-COV2 reduced the amount of virus and associated damage in the lungs of non-human primates.”According to Regeneron, the treatment has been tried on hospitalized and non-hospitalized patients and as a preventative for those who have had close contact with coronavirus patients. So far, the drug has been particularly promising for non-hospitalized patients.Regeneron said the treatment reduces the viral load from the coronavirus, and boosts the body’s immune response to the virus. 2890

Protests, elections, COVID-19--these are some of the factors experts say are leading to the rise of gun sales this year.“There’s just so much happening right now to make people feel uncertain, and I think that’s the one thing that might explain gun sales,” said Trent Steidley, a sociologist and Assistant Professor at the University of Denver.Steidley focuses on topics like firearms and society.“First, it was COVID to think about. OK, people are probably feeling unsure about a lot of things, and we know uncertainty kind of correlates with gun sales. It can go with things like a recession, it can go with things like unemployment,” he explained. “What we've seen now is about four months of pretty heavy gun sales.”A firearm industry survey conducted by the NSSF showed handguns outpaced shotguns 2 to 1 in sales among first-time gun buyers, following a larger, rising trend Steidley has been watching.“Before 2012, 2013, long guns, shotguns, rifles, consistently outpaced handguns. Slowly over time, that ratio changed though,” he said.FBI firearm background check data appears to coincide with two major events. The top two highest weeks for checks since 1998 were March 16 through March 22 of this year with 1,197,788 checks, and June 1 through June 7 with 1,004,798 checks. For reference, March 13 was the day President Donald Trump announced the national emergency for coronavirus and May 25 was the day of George Floyd’s death in Minneapolis.“It’s human nature. People feel threatened in some way, either they feel their rights might be threatened,” Sheriff Justin Smith in Larimer County, Colorado said. “You can’t go on the internet or watch TV and pick up the news and not see some very concerning stories on spikes in violence around the country.”Smith said his department has seen an increase in those applying for concealed handgun permits.“The numbers are certainly on the increase. We just can’t say because a lot of folks are stuck waiting. We’re clear into September on appointments right now, but I definitely get that sense those numbers are up,” he said.The response from Steven Reams, Weld County Sheriff, echoed the same:“I’ve definitely seen a marked increase in concealed weapon permit applications. It started to increase in mid-March and then there was a dramatic increase in June, and then another in July. It seems that most applicants are not necessarily all new gun owners, more than half are people who just decided it was a good time to start carrying. The balance of the applicants are largely first time gun buyers.”Surveys from the NSSF show firearm retailers believe 40 percent of all guns purchased this year have been by first-time buyers, which has brought training and safety to the forefront.“Representatives of the industry and trainers are all aware there's a need to get these people trained up on how to use a gun safely, how to store a gun, proper safety protocols,” Steidley said.“Training is a must,” Steve Allred said. “I would say probably 50 percent of my students never even held a gun.” Allred leads gun safety and self-defense courses in Wyoming. COVID-19 impacted what he’s able to do, but thanks to technology, he’s figured out a solution.“We ran five, six, seven classes every year in the summer mainly,” he said. “April is usually when we start classes. We just decided everyone's kind of going to the Zoom thing. Anyways, we can provide the class live.”There are limitations of what Allred can teach virtually, but he offers anyone who takes the class to join him on the range, as well.“What it’s allowed us to do is it's allowed us to instead of concentrate locally, we’re having students all over the country,” he said.While feelings of uncertainty fuel firearm sales, Allred said no matter someone’s reason for buying a gun, it’s important they know how to use it.“Why do I want a gun? Why do I push my wife to train with her weapon? And it boils down to just the ability to protect when you least expect it,” he said. 3992

Rep. Chris Stewart on Tuesday defended President Donald Trump's response to the death of Washington Post journalist Jamal Khashoggi in the Saudi Consulate in Istanbul in October, saying that "journalists disappear all over the country.""We have to have a relationship with some players we don't agree with," the Utah Republican told CNN's Brianna Keilar on "CNN Right Now." "Journalists disappear all over the country.""This is a very, very difficult challenge because we have to, on one hand, hold them accountable -- including the crown prince for whatever action he may have been involved with," Stewart added. "And at the same time what is protecting US interests? What is going to counter Shia extremists? What is going to help bring stability? What will help bring an end to the war in Yemen? You have to balance all those considerations as we move forward on this."After being subjected to massive international pressure, Saudi officials admitted the death of Khashoggi was a premeditated murder.Trump responded?to the incident in a statement last month subtitled "America First!" that called Khashoggi's murder "terrible" but declared Saudi Arabia "a great ally"On Tuesday, lawmakers were briefed by CIA Director Gina Haspel about the incident.Sen. Bob Corker, a Tennessee Republican who chairs the Senate Foreign Relations Committee, told CNN after the briefing with Haspel that Saudi Crown Prince Mohammed bin Salman "ordered, monitored, the killing" of Khashoggi.When pressed on Trump's dismissive response to the incident, Stewart added, "I think all of us agree there needs to be an appropriate response here, we need to hold individuals accountable and we need to completely understand the facts regarding that as well." 1757

President Trump has removed Rex Tillerson as his Secretary of State, replacing him with CIA head Mike Pompeo.CIA Deputy Director Gina Haspel will replace Pompeo as the head of the CIA."Mike Pompeo, Director of the CIA, will become our new Secretary of State. He will do a fantastic job! Thank you to Rex Tillerson for his service! Gina Haspel will become the new Director of the CIA, and the first woman so chosen. Congratulations to all!" President Trump tweeted Tuesday morning.  494

President Donald Trump signed two pieces of legislation into law on Wednesday that aim to inform consumers about drug prices.Both measures, the Know the Lowest Price Act and the Patient Right to Know Drug Prices Act, aim to end the drug industry's so-called gag orders of pharmacists, which prevent them from discussing cheaper price options with consumers. These price options include discussing whether a medication may be less expensive if using insurance or paying out-of-pocket.At Wednesday's signing, the President called the gag clauses "unjust" and said the legislation would lower drug prices that are "way out of whack" and "way too high.""It's called the law of supply and demand. They didn't want to have that. But now we have that and it's going to lower drug prices," Trump added.Both the President and Health and Human Services Secretary Alex Azar said at the signing that they expect further regulatory action on reducing drug prices in the coming months.Some states and municipalities have pharmacy gag order bans, but the Patient Right to Know Drug Prices Act, sponsored by Maine Republican Sen. Susan Collins, addresses banning the practice of gag orders on a federal level. The Know the Lowest Price Act, sponsored by Michigan Democratic Sen. Debbie Stabenow, prohibits Medicare drug plans from putting a gag clause on a pharmacy in their contracts.Collins and Stabenow were present at Wednesday's signing, as well as Tennessee Republican Sen. Lamar Alexander, Louisiana Republican Sen. Bill Cassidy, Deputy Attorney General Rod Rosenstein and National Economic Council Director Larry Kudlow.Some pharmaceutical industry experts say that although eliminating the gag clause is step toward consumer transparency, it doesn't address the issue of lowering actual drug costs, making it unclear how much of a tangible effect the legislation will have.The President has frequently expressed his frustration over rising drug prices, and in May, he laid?out his vision for increasing competition, reducing regulations and changing the incentives for all players in the pharmaceutical industry.The administration released a 44-page blueprint of the plan, entitled American Patients First, aiming to increase competition and improve the negotiation of drug prices, as well as reduce consumers' out-of-pocket spending on medicines and create incentives to lower list prices.Ending the pharmacy gag orders was included the plan, as well as speeding up the approval of over-the-counter medications and asking the Food and Drug Administration to require manufacturers to include prices in their TV ads.A gag order on a pharmacy is frequently brought on by clauses in contracts with pharmaceutical benefit managers, which manage most of our nation's prescription drug programs. The benefit managers negotiate prices with drug companies on behalf of insurance companies and other payers and then share those prices to retail pharmacies. They also negotiate rebates from manufacturers and discounts from drugstores. If pharmacists violate the gag rule, they risk losing their contract with the pharmaceutical benefit manager.Daniel Nam, executive director of federal programs at America's Health Insurance Plans, told Kaiser Health News that gag orders on pharmacies are becoming less frequent because these clauses are "not something they are incorporating into their contracts."Mark Merritt, president and CEO of a lobbying group for pharmaceutical benefit managers, the Pharmaceutical Care Management Association, told the publication that these clauses are "very much an outlier." 3635

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