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BEIJING, Nov. 22 (Xinhuanet) -- Underweight patients may have more possibilities of mortality within 30 days of general and vascular surgery compared with mildly obese patients, according to a research published online in Archives of Surgery Tuesday.Researchers at the U.S. National Surgical Quality Improvement Program conducted the research for the years 2005 and 2006, and assessed the contribution of BMI (Body Mass Index) to 189,533 postsurgeries morbidity and mortality by obesity classes.They found that compared with the middle BMI quintile group, patients with BMI value below 23.1, had greater chances for death. For the highest BMI quintile group, higher mortality rate was also observed.However, the researchers also found that obesity may as well be associated with increased mortality for some individual types of surgeries."These individual types of procedures include procedures with which the general surgeon should have definite experience: colorectal resection, colostomy formation, cholecystectomy, hernia repair, mastectomy, and wound debridement," said George J. Stukenborg, PhD, of the University of Virginia inCharlottesvilleand his colleagues.Based on a 30 –day morbidity and mortality risk calculation, the sample patients were categorized into BMI quintile ranges. BMI value of less than 23.1 was considered as lowest, values from 26.3 to 29.6 considered as the middle quintile, and above 35.2 considered as the highest.Factors such as lack of enough data on nonfatal complications and hospital resources, or examining mortality over the 30-day baseline, may cause limitations and inaccuracy to the research and more studies on a wider range of patients in terms of BMI are needed to further confirm the current conclusion, researchers said.

BEIJING, Oct. 13 (Xinhuanet) -- A new study finds that ginger may decrease the risk of colon cancer through diminishing the inflammation in the gut, according to media reports Thursday.Prior researches have found that chronicle inflammation in the gut is related to colon cancer, suggesting easing inflammation in intestines might reduce the risk of the cancer, said Suzanna M. Zick, lead author of the study published online in Cancer Prevention Research. Zick, also a naturopathic physician and research associate professor at University of Michigan Medical Center, and her colleagues, assigned 30 volunteers to take pills containing two grams of either placebo powder or ginger root extract, equivalent to about two tablespoons of ground-up raw ginger root.And they recorded the inflammations in the participants' intestines before and after the test period.The researchers found that participants taking ginger pills had 28 percent less inflammation in their intestines after the test. But no difference was found in those who took placebo.The findings are promising, but the researchers are not yet recommending people start taking more ginger at meal times. The study only involved 30 participants, so it is just a preliminary study. Zick said they hope to launch a larger study in the future, according to USA Today.

SAN FRANCISCO, Nov. 21 (Xinhua) -- Hewlett-Packard Co. (HP) on Monday reported that its profit in the most recent quarter fell more than 90 percent with sales also declining.In the company's fourth quarter of fiscal 2011 ended Oct. 31, the company posted net earnings of 239 million U.S. dollars, compared with 2.54 billion dollars in the same period a year earlier.HP's net revenue for the quarter reached 32.1 billion dollars, down 3 percent year-on-year.Excluding one-time items, HP earned 1.17 dollars per share, which topped estimates of analysts.According to Thomson Reuters, analysts had expected earnings of 1.13 dollars per share on revenue of 32.05 billion dollars.It was the first earnings report since Meg Whitman took over as chief executive officer (CEO) of the information technology giant on Sept. 22, replacing Leo Apotheker."HP has a great opportunity to build on our strong hardware, software, and services franchises with leading market positions, customer relationships, and intellectual property," Whitman said in a statement after the earnings announcement."We need to get back to the business fundamentals in fiscal 2012, including making prudent investments in the business and driving more consistent execution," she added.

WASHINGTON, Dec. 7 (Xinhua) -- The use of two drugs never tried in combination before in ovarian cancer resulted in a 70 percent destruction of cancer cells already resistant to commonly used chemotherapy agents, say researchers at Mayo Clinic in Florida.Their report, published on-line Wednesday in Gynecologic Oncology, suggests that this combination, ixabepilone and sunitinib, might offer a much needed treatment option for women with advanced ovarian cancer.Neither drug is approved for use in ovarian cancer. Ixabepilone is a chemotherapy drug that, like other taxane drugs, targets the microtubules and stops dividing cells from forming a spindle. It has been approved for use in metastatic breast cancer. Sunitinib, approved for use in kidney cancer, belongs to a class of tyrosine kinase inhibitors that stops growth signals from reaching inside cancer cells.When caught at late stages, ovarian cancer is often fatal because it progressively stops responding to the chemotherapy drugs used to treat it."Women die from ovarian cancer because their tumors become resistant to chemotherapy, so a drug that might be able to reduce that resistance -- which may be what this combination of agents is doing -- would be a boon to treatment of this difficult cancer," says study coauthor Gerardo Colon-Otero.The finding also highlights the importance of the role of a molecule, RhoB, that the researchers say is activated by the drug duo. It might be a potential biomarker that may help identify patients who might benefit from such combination therapy, the researchers say.

WASHINGTON, Dec. 5 (Xinhua) -- Young women may reduce their risk of developing cardiovascular disease simply by eating more fish rich in omega-3 fatty acids, researchers reported Monday in Hypertension: Journal of the American Heart Association.In the first population-based study in Danish women of childbearing age, those who rarely or never ate fish had 50 percent more cardiovascular problems over eight years than those who ate fish regularly. Compared to women who ate fish high in omega-3 weekly, the risk was 90 percent higher for those who rarely or never ate fish.About 49,000 women, 15-49 years old, median age of just under 30 years in early pregnancy -- were interviewed by telephone or answered food frequency questionnaires about how much, what types and how often they ate fish, as well as lifestyle and family history questions.Researchers recorded 577 cardiovascular events during the eight- year period, including five cardiovascular deaths in women without any prior diagnosis of the disease. In all, 328 events were due to hypertensive disease, 146 from cerebrovascular disease, and 103 from ischemic heart disease. Inpatient and outpatient admission for cardiovascular disease was much more common among women who reported eating little or no fish. In three different assessments over a 30-week period, women who never ate fish had a three-fold higher disease risk compared to women who ate fish every week."To our knowledge this is the first study of this size to focus exclusively on women of childbearing age," said Marin Strom, lead researcher and post doctoral fellow at the Center for Fetal Programming, at Statens Serum Institute in Copenhagen, Denmark. " We saw a strong association with cardiovascular disease in the women who were still in their late 30's."Fish oil contains long chain omega-3 polyunsaturated fatty acids, which are believed to protect against heart and vascular disease. Few women in the study took fish oil supplements, so these were excluded from the analyses and the results were based on the dietary intake of omega-3 fatty acids, not intake from supplements.The most common fish consumed by women in the study were cod, salmon, herring, and mackerel."Our study shows that for younger women, eating fish is very important for overall health, and even though we found cardio- protective effects at relatively modest dietary levels, higher levels may yield additional benefits," Strom said.

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