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CAMBRIDGE, Mass. – The U.S. government will pay Moderna Inc. up to .525 billion to secure 100 million doses of the company’s COVID-19 vaccine candidate.The U.S. Department of Health and Human Services (HHS) and Department of Defense (DoD) made the announcement Tuesday.HHS says Moderna will manufacture the vaccine doses while clinical trials are still underway to expedite the traditional development timeline and get vaccines to the public as soon as possible.The Trump administration hopes to deliver the vaccines by the end of the year, so long as the U.S. Food and Drug Administration (FDA) authorizes their use.“In creating a vaccine portfolio for Operation Warp Speed, the Trump Administration is increasing the likelihood that the United States will have at least one safe, effective vaccine by 2021,” said HHS Secretary Alex Azar. “Today’s investment represents the next step in supporting this vaccine candidate all the way from early development by Moderna and the National Institutes of Health, through clinical trials, and now large-scale manufacturing, with the potential to bring hundreds of millions of safe and effective doses to the American people.”HHS says the vaccine doses will be delivered to government-designated locations across the country and the U.S. could acquire up to an additional 400 million doses of the vaccine.If viable, the vaccines would be available to the American people at no cost, according to HHS. Healthcare professionals could charge for the cost of administering the vaccine, though.The vaccine, called mRNA-1273, has been co-developed by Moderna and scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The third phase of the vaccine trial, which began July 27, is the first government-funded Phase 3 clinical trial for a COVID-19 vaccine in the nation, according to HHS.“We appreciate the confidence of the U.S. government in our mRNA vaccine platform and the continued support,” said Stéphane Bancel, Moderna’s Chief Executive Officer. “We are advancing the clinical development of mRNA-1273 with the ongoing Phase 3 study being conducted in collaboration with NIAID and BARDA. In parallel, we are scaling up our manufacturing capability with our strategic partners, Lonza, Catalent and Rovi, to address this global health emergency with a safe and effective vaccine.” 2402

By mid-afternoon on Wednesday, some of the streets of Louisville were filled with demonstrators upset by a Kentucky grand jury decision not to charge two of the officers involved in fatally shooting Breonna Taylor in her home in March.On Monday, the city was placed in a state of emergency with the expectation that protesters and law enforcement would clash. Many downtown businesses were boarded up and police officers were called back from vacations.As of 9 p.m. ET, the city went under a mandatory curfew.Thirty minutes before the curfew order went into effect, two Louisville officers were shot amid the protests. The officers were hospitalized but expected to survive, Louisville Metro Police said.Brett Hankison was the only officer charged among those who participated in the raid on the apartment where Taylor lived. Hankison’s charges, however, were not directly in response to Taylor’s shooting. He was charged with wanton endangerment for firing gun shots at other apartments.Two other officers, Jon Mattingly and Myles Cosgrove, are not facing charges. Kentucky Attorney General Daniel Cameron considered their use of force justified.Hankison, Mattingly and Cosgrove returned fire during the raid after Taylor's boyfriend Kenneth Walker fired at the officers. Walker was arrested but had his charges dropped due to the belief that the officers were breaking into the apartment.Ben Crump, a civil rights attorney representing the Taylor family, called the lack of charges “outrageous and offensive.”“This is outrageous and offensive to Breonna Taylor’s memory. It’s yet another example of no accountability for the genocide of persons of color by white police officers. With all we know about Breonna Taylor’s killing, how could a fair and just system result in today’s decision? Her killing was criminal on so many level," Crump said.The NAACP called Taylor’s death “murder.”“The injustice we’re witnessing at this moment can be sensed throughout the nation. Kentucky’s Attorney General Daniel Cameron’s failure to bring substantial charges against the officers who murdered Breonna Taylor causes angst and pain for far too many Americans still reeling from a pandemic,” the NAACP said in a statement. “The charges of wanton endangerment in connection with the murder of Breonna Taylor does not go far enough and is a miscarriage of justice for her family and the people of Louisville. Atrocities committed against the people of this country by the authorities cannot and should not go unanswered when miscalculations are made. The continuous and blatant failure of a system sworn to protect the very citizens it endangers is all too telling of its efficiency and viability.”While some protesters demonstrated peacefully, others have ignored calls for peace.Raw video from the protests in Louisville showed a small group of protesters fighting with officers. Several of the demonstrators were detained. 2923

CHAPEL HILL, N.C. - Vaping and COVID-19.Could using e-cigarettes put you at greater risk for viral infections like coronavirus or the flu? It's a question researchers at the University of North Carolina (UNC) are looking into in the midst of the pandemic.“E-cigarette use has been shown, from this study, not to be safe,” Dr. Meghan Rebuli, Assistant Professor with the UNC Department of Pediatrics said.Rebuli and others at UNC are studying the impacts of viral infections on e-cigarette users.“We want to know what factors will affect someone more, so will smoking make you more at risk for COVID-19, or will e-cigarette use make you more at risk for COVID-19?"In their study, researchers found vaping e-cigarettes could impair your body's normal immune response to viral infections.“E-cigarette users and smokers had a less powerful immune response against the virus,” Rebuli said.“What we found is that these genes and proteins that are really critical to making sure that your immune process and your immune response to this virus is working at top capacity, are impaired,” Rebuli added. “This is really critical when it comes to respiratory viruses and could also potentially be applicable to something like the coronavirus.”News 3 Medical Expert Dr. Ryan Light said this study is important to cut back or stop e-cigarette use to keep you safe.“As we find more out about e-cigarettes, we find that they're more dangerous than we once thought,” Light said. “An ounce of prevention, at this point, is worth a pound of cure.”Both Light and Rebuli believe it's also a reminder to keep up with health guidelines during the pandemic, especially if you vape.“Maybe this should indicate that they need to take kind of hypervigilance or hyperawareness when they're using PPE; when they're maintaining six-foot distance; when they're washing their hands,” Rebuli said.This story was first reported by Zak Dahlheimer at WTKR in Norfolk, Virginia. 1949

CHARLOTTE, NC (WGHP) -- Crowds lined up to see Billy Graham’s funeral motorcade bring his casket from Asheville to Charlotte on Saturday.The motorcade left Asheville at about 11 a.m. and brought his casket to the Billy Graham Library shortly before 3 p.m.Graham, an evangelical minister and spiritual confidant to American presidents, died at the age of 99 on Wednesday.Graham “spread the gospel in 185 countries during his 99 years on Earth, touching the lives of many and forever changing the course of the world’s spiritual health,” according to a statement by House Speaker Paul Ryan.Graham’s private funeral will be held on Friday, March 2 at the Billy Graham Library in Charlotte, North Carolina.About 2,300 guests have been invited, including President Donald Trump, Vice President Mike Pence, and every living former president.Billy Graham Evangelistic Association confirmed that George W. Bush and his wife Laura will attend the repose on Monday, but not the funeral. The organization couldn’t confirm if any other former presidents, President Trump or Vice President are attending any events next week.Graham will lie in repose in his childhood home, which was moved to Charlotte several years ago, on Monday, February 26 and Tuesday, February 27. The public will be invited to pay respects from 8 a.m. to 10 p.m. on both days.The minister will be buried next to his wife, Ruth, on the property. His coffin, a plain, pine casket, was built by inmates at the Louisiana state prison. 1499

CARACAS, Venezuela — Six American oil executives held for three years in Venezuela have been found guilty of corruption charges and immediately sentenced to prison.The judge’s ruling Thursday came with sentences of more than eight years for each defendant.The verdicts dashed the hopes of relatives for a quick release that would send the men home to the United States.The so-called Citgo 6 had been lured to Venezuela three years ago for a business meeting and arrested. They are employees of the Houston-based Citgo refining company, which is owned by Venezuela’s state oil company, PDVSA.Attorneys and relatives of the executives say the men were wrongly convicted.“We, the family, are heartbroken to be separated even further from our loved ones,” Alirio Rafael Zambrano, whose two brothers were among the defendants, told The Associated Press. “We pray that the leaders of our nation step forward and continue to fight unceasingly for their freedom and human rights.”An attorney who represented three of the defendants called the judge's decision "void of any evidence." 1083

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