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WELLINGTON, May 24 (Xinhua) -- New Zealand researchers have found a way to stop the growth of certain cancer tumors by " silencing" a group of PAX genes, members of a small family of genes that play important roles in embryonic development, but also allow cancer cells to grow and divide in adult tissue.In an article published in UK medical journal Oncogene, Otago University Professor Michael Eccles and colleagues revealed how they used the PAX8 gene to kill cancer cells.After detecting high levels of PAX8 protein in the majority of kidney, ovarian and thyroid cancers they studied, the researchers used molecular techniques to silence the PAX8 gene in several cancer cell lines."We found that these PAX8-depleted cancer cells ceased growing and dividing. The cells were essentially stopped in their tracks through the failure of multiple mechanisms and pathways crucial to their cell division cycle. They then entered into a state called senescence in which they no longer divided, and after that they ultimately died," Eccles said in a statement from the university Tuesday.The findings suggested that PAX8 could be a good target for the development of new cancer therapies, he said."Any resulting drugs would be a long way down the road, but in the meantime this research helps confirm that a focus on PAX genes may prove to be a fruitful line of attack against a number of cancers," he said.The research was supported by grants from the Health Research Council of New Zealand. It formed the main piece of work carried out by Otago doctoral graduate Caiyun (Grace) Li, now a postdoctoral fellow at Stanford University. Study co-authors also included Professor Antony Braithwaite and master's student Jen Nyman.In 2003, research led by Eccles discovered that proteins from one or more of the nine PAX genes were present in many common cancers. They found that "silencing" the gene expression of PAX2 in ovarian and bladder cancer cells, and of PAX3 in melanoma, led to the rapid death of the cells.
BEIJING, March 10 (Xinhuanet) -- The price of preventing preterm labor is about to rise drastically in the U.S. next week.A drug for high-risk pregnant women costs about 10 to 20 dollars per injection. Next week, the price will shoot up to 1,500 dollars a dose, according to media reports Wednesday.This means the total cost during a pregnancy could be as much as 30,000 dollars.The massive increase comes after KV Pharmaceutical of St. Louis won an exclusive government license to produce the drug, known as Makena.The drug, a form of progesterone given as a weekly shot, has been made cheaply for years by unlicensed chemists.The March of Dimes and many obstetricians supported the move because it means quality will be more consistent and it will be easier to get, but none of them has anticipated the sharp price hike.Doctors and campaign groups have been caught out by the move, saying that the price hike may deter low-income women from getting the drug, leading to more premature births.
CAIRO, Jan. 23 (Xinhua) -- The first training session for Egyptian Chinese language teachers to improve their teaching ability started on Sunday in Cairo.The session, under the supervision of the Chinese Confucius institute, will concentrate on the exchange of experiences in teaching the Chinese language in Egypt and the enhancement of Egyptian teachers' ability to make better use of the textbooks.The three-day training session will contain language and cultural courses by professors and instructors from famous Chinese universities such as Beijing University and Beijing Foreign Studies University, said Li Shengjun, head of the Confucius Institute at Cairo University.Nearly 60 Egyptian Chinese language teachers, including 14 professors, from universities including Cairo University, Ain Shams University and Minya University will attend the training courses.China has established 691 Confucius institutes and classes in around 69 countries until 2010, including nine in the Arab countries.
BEIJING, Jan. 20 (Xinhua) -- China on Thursday announced it had introduced a regulation to better manage state compensation funds. The regulation was signed by Chinese Premier Wen Jiabao Monday and immediately came into effect then.The regulation is aimed to ensure eligible claimants receive state compensation on time and in full.The regulation means governments at all levels must budget for state compensation payouts each year, and if the actual amount of state compensation payouts exceed what is budgeted for, additional funds must be used.The regulation also standardizes the procedure of applying for state compensation.State compensation refers to government pay outs to citizens for damages it has caused them through infringements of their rights.The State Compensation Law of China took effect since 1995.
BEIJING, Feb. 10 (Xinhua) -- China's drought control authorities announced Thursday that hours of snowfall and irrigation have eased to some extent the severe drought in parts of the nation.Rapid spreading of the dry spell in the country's winter wheat producing regions has been curbed by wide-spread snowfall in the areas along the Yangtze, Huaihe and Yellow rivers and in the country's northern part on Wednesday and Thursday, the Office of State Flood Control and Drought Relief Headquarters said in a statement on its website.Drought-hit areas in Henan and Anhui, which are two major wheat-producing provinces, were reduced by 6.3 million mu (420,000 hectares) and 4.1 million mu, respectively, from Wednesday, the statement said. The agency added that irrigation also contributed to easing the effects of the drought.The statement said that as of Thursday, eight drought-hit provinces had irrigated 143 million mu of drought-affected wheat producing areas, which accounts for 52 percent of the combined winter wheat producing areas in the provinces. The eight provinces include the territories of Shandong, Henan, Hubei, Anhui, Shanxi, Shaanxi, Gansu and Jiangsu.As of 3 p.m. Thursday, the drought had affected 101.28 million mu of crops nationwide and left 2.81 million people and 2.57 million heads of livestock short of drinking water, said the statement.Cloud seeding on Wednesday and Thursday during a recent cold front, also helped alleviate drought in some regions, according to a report posted on the website of the China Meteorological Administration on Thursday.The report also said that the artificial precipitation had mitigated the shortage of moisture in the soil in parts of Henan and Anhui. The situation is expected to improve as the rain and snow continues.However, experts urged more measures from local governments to ensure winter wheat production since the current precipitation is not adequate to "completely ease the drought", the report said.