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2025-05-31 07:59:22
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  下肢静脉血栓哪家看的好成都   

SAN DIEGO (KGTV) — Target cash registers suffered a nationwide outage Saturday, leaving some customers around the country sitting in line for hours.The company's corporate office said an "internal technology issue" shut down registers for about two hours Saturday, preventing customers from making purchases in store.Target added that the technology issue was not a data breach or security-related issue and that customer data was no compromised. By 2:30 p.m., Target said their systems were back online:"Target’s registers are fully back online and guests are able to purchase their merchandise again in all stores. The temporary outage earlier today was the result of an internal technology issue that lasted for approximately two hours. Our technology team worked quickly to identify and fix the issue, and we apologize for the inconvenience and frustration this caused for our guests. After an initial but thorough review, we can confirm that this was not a data breach or security-related issue, and no guest information was compromised at any time. We appreciate all of our store team members who worked quickly to assist guests and thank everyone involved for their patience."10News has reached out to Target to see how many stores in San Diego were affected by the outage, but have not heard back.Twitter users across the country took to chronicle their "#TargetDown" experience online, ranging from long wait times, abandoning carts full of groceries, and some checking in — and out — of work at a location as the outage continued.#targetdown I was able to get out in a little over an hour because my cashier would not give up. He had to scan every single item at least 10 times but it worked. They are still turning away people at the door. pic.twitter.com/jbEzBcIjmj— Naomi Thompson ?? (@NaominotNyomi) June 15, 2019I moved from Manhattan to Brooklyn this morning faster than I can check out at @Target. #TargetDown pic.twitter.com/Eko97zgXBS— tanya (@thetiebandit) June 15, 2019I was at Target. Seems to be no end in site for the register outage or the forming lines. I abandoned cart and left... can't waste my whole day there. #targetdown #targetoutage pic.twitter.com/IolXjTIjOz— Jeff of The Game Capital & The Poke Capital (@ThePokeCapital) June 15, 2019Every Target register in the country is down! This is crazy. Been on line for 30 minutes!!#targetdown pic.twitter.com/MLPcP6QEng— IceburG?? (@So_Ice_Cold) June 15, 2019Just left target after patiently waiting for an hour or so. Every single person working there is amazing & I honestly feel for them. I just had to take the L. If you’re still there, please be patient with these guys. They are doing their best! #targetdown pic.twitter.com/yBcEYL4Jsx— Elizabeth Matthews (@momof2boys79) June 15, 2019A similar issue hit Target stores in 2014. That outage appeared to be a "glitch" causing delays at checkouts, "but is not in any way related to a security issue." 2951

  下肢静脉血栓哪家看的好成都   

SAN DIEGO (KGTV) - The holidays are creeping into San Diego County this weekend.El Cajon's annual Mother Goose parade will headline the weekend, marking a Thanksgiving tradition San Diegans have participated in for years.The weekend will also see a couple of holiday events get underway, including the Global Winter Wonderland set up at SDCCU Stadium and Encinitas Holiday Fair.Here's a look at what's happening this weekend:18th annual San Diego Asian Film Festival at San Diego Natural History Museum - Thursday - SaturdayMore information.Film buffs will experience more than 150 films from 20 countries in 30 languages spanning action, romance, comedy, drama, animation, documentaries, and family-friendly films. Q&As with filmmakers, opportunities to meet cast and crew and podcast panels will also be hosted. 835

  下肢静脉血栓哪家看的好成都   

SAN DIEGO (KGTV) -- Termed-out San Diego City Councilman Scott Sherman is taking aim at what he says is too much outside influence behind the scenes at City Hall.In an interview with ABC 10News, Sherman said too many of his colleagues vote based on their own political preservation."Unfortunately, too many politicians are looking down the road and at what office they are going to run for next," Sherman said. In a recent op-ed, Sherman said in politics he has learned that handshakes and signed memos are worth a "bucket of spit." He said political gadflies, union reps, party reps and political donors are wielding too much power of council members. Sherman believes this is the reason the city still has not come to an agreement on regulating short-term rentals, and is approving labor-friendly development projects."One of the things that bothered me the most in politics is how different special interest groups can literally come down, sit in the front row, and dictate to council members what they will and won't do if they want their support in the future, and unfortunately most of them do," Sherman said. Sherman said he is the exception because he did not base his council career on a run for higher office. He did run for mayor in 2020, losing in the primary. But he said chose to run because of encouragement, and because no other Republican entered the race. Michael Zucchet, who heads the city's Municipal Employees Association, said Sherman and other politicians generally define "special interests" as those that disagree with them. "I wasn't very moved by his comments and they struck me as sour grapes," Zucchet said in an email. "It seems like pure hypocrisy to me. Not to mention baseless, transparent whining."Sherman, who represented the Mission Valley area, is now going back into insurance sales. His departure will leave Chris Cate as the only Republican on the City Council because Sherman's seat flipped to Democrat in the November election. 1978

  

SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223

  

SAN DIEGO (KGTV) — The family of a Navy sailor nearly killed in Syria is starting the new year with one less challenge.Over a year ago Navy EOD Tech Kenton Stacy was left paralyzed after an IED explosion. As Stacy was recovering in San Diego, renters were destroying the family’s Virginia home. “Just with everything we’re going through, it added stress. I just couldn’t believe how someone could damage our home and be okay with it,” said Kenton’s wife Lindsey.The home reeked of cigarettes, and the carpet, walls, and blinds were destroyed. When the EOD community in Virginia learned what happened in November they began to make repairs on the home.Julie Fish, a real estate agent with Signature Realty Select, also stepped in to help, taking over as the realtor.After reaching out for more help, people around the country offered money, time, services and resources. “These guys are...it’s like a brotherhood, there’s nothing they wouldn’t do for one another, and I like to think the wives are the same way,” said Fish, whose husband is also a Navy EOD Tech. Less than two months later, the home looks brand new and is on the market. “Very blessed that they just took that burden off of us, one less thing that we had to worry about, stress out about, and we just can’t thank everyone enough,” said Lindsey.Anyone interested in purchase the Virginia house can learn more about it here. 1396

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