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WASHINGTON, June 16 (Xinhua) -- Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage. New research by a team of scientists at the University of Rochester has unveiled an important new mechanism that allows cells to recognize when they are under stress and prime the DNA repair machinery to respond to the threat of damage.Their findings will be published Friday in journal Science. Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage.The scientists, led by biologists Vera Gorbunova and Andrei Seluanov, focused on the most dangerous type of DNA damage -- double strand breaks. Unrepaired, this type of damage can lead to premature aging and cancer. They studied how oxidative stress affects efficiency of DNA repair. Oxidative stress occurs when the body is unable to neutralize the highly-reactive molecules, which are typically produced during routine cellular activities.The research team found that human cells undergoing oxidative stress synthesized more of a protein called SIRT6. By increasing SIRT6 levels, cells were able to stimulate their ability to repair double strand breaks. When the cells were treated with a drug that inactivated SIRT6, DNA repair came to a halt, thus confirming the role of SIRT6 in DNA repair. Gorbunova notes that the SIRT6 protein is structurally related to another protein, SIR2, which has been shown to extend lifespan in multiple model organisms."SIRT6 also affects DNA repair when there is no oxidative stress," explains Gorbunova. "It's just that the effect is magnified when the cells are challenged with even small amounts of oxidative stress."SIRT6 allows the cells to be economical with their resources, priming the repair enzymes only when there is damage that needs to be repaired. Thus SIRT6 may be a master regulator that coordinates stress and DNA repair activities, according to Gorbunova.

BEIJING, Sept. 6 (Xinhuanet) -- San Francisco police said they had helped Apple search for a "lost item," following reports saying that a prototype of Apple's yet-to-be-released iPhone 5 had gone missing in July.Last week, technology news website CNET reported that an Apple employee lost at a tequila bar in San Francisco in July a prototype of iPhone 5, a new version of the company's mobile phone expected to be released in September or October.The San Francisco Police Department said in a press release that after the missing device was tracked using GPS technology to a San Francisco house, four police officers and two Apple employees visited the home."Apple employees called Mission police station directly, wanting assistance in tracking down a lost item," the statement said."The two Apple employees met with the resident and then went into the house to look for the lost item," it said. "The Apple employees did not find the lost item and left the house."Police did not say exactly what Apple had lost, but media reports found the file of San Francisco police's Friday press release about the hunt was named "iphone5.doc" -- an apparent hint of the new mobile device.A 22-year-old resident of the home, identified by SF Weekly as Sergio Calderon, told the newspaper that he has visited the bar where the phone was reportedly lost but he did not have the device.Calderon said the search of his house took place in July when police had traced the phone to the house using satellite positioning software on the device, but did not find anything in the house.Apple has declined to comment on the matter.Last year, an employee of the company lost a prototype iPhone 4 in a Redwood City bar before it was released. The details of the phone ware then unveiled by technology blog Gizmodo.Criminal charges have been filed against the man who found the prototype and another who brokered the deal to sell it to Gizmodo. Both men pleaded not guilty on Thursday.

BERLIN, June 5 (Xinhua) -- German authority said on Sunday that bean sprouts might be the "most convincing" source for the E. coli outbreak which has killed 22 people and infected more than 2,000 in the Europe.Gert Lindemann, Agriculture Minister of the state Lower Saxony, told reporters in a press conference that restaurants and food outlets where the cases of E. coli had been reported all had received shipments of the particular bean sprouts.A related company in the Uelzen region has been shut down and its products have been recalled, he said."It is the most convincing... source for the E. coli outbreak," Lindemann said. Although a conclusive laboratory analysis will not come out until Monday, current indications were strong enough to issue a public warning, he said.Authorities have been racing to track down the source of the pathogen since the outbreak, which has infected people in 12 countries - all of whom had once traveled in northern Germany. More than 600 of those infected have developed Hemolytic Uremic Syndrome (HUS), a potentially deadly complication attacking the kidneys.The source of E.coli was first thought to be the cucumbers from Spain, which has caused huge loses for Spain farmers. However, this conclusion was overthrown by Laboratory tests in Hamburg on Tuesday.

BEIJING, June 14 (Xinhuanet) -- A biographical comic book of Apple's CEO Steve Jobs will hit the shelves in August, according to media reports Tuesday. Titled "Steve Jobs: Co-Founder of Apple", the 32-page comic book, which details the life and career of Jobs, will be published by Bluewater Productions Inc. "His innovations command front page news, speculation of his health affects the stock market. Not bad for a college dropout," Bluewater president Darren Davis said in a statement. "His story, and that of Apple, is epic." Apple CEO Steve Jobs.The book, priced at 3.99 U.S. dollars, was written by C.W. Cooke and drawn by Chris Schmidt. The publisher's intention to make Jobs as its subject came from the success of the comic biography of Facebook founder Mark Zuckerberg. "There are definitely some similarities between Zuckerberg and Jobs. It takes a certain kind of drive and a certain kind of genius to move society the way they have," said C.W. Cooke. In addition, the first authorized biography of Jobs, "iSteve: The Book of Jobs", will be released on March 6, 2012.