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Bulked-up, mutant “mighty mice” held onto their muscle during a monthlong stay at the International Space Station, returning to Earth with ripped bodybuilder physiques, scientists reported Monday.The findings hold promise for preventing muscle and bone loss in astronauts on prolonged space trips like Mars missions, as well as people on Earth who are confined to bed or need wheelchairs.A research team led by Dr. Se-Jin Lee of the Jackson Laboratory in Connecticut sent 40 young female black mice to the space station in December, launching aboard a SpaceX rocket.In a paper published in the Proceedings of the National Academy of Sciences, Lee said the 24 regular untreated mice lost considerable muscle and bone mass in weightlessness as expected — up to 18%.But the eight genetically engineered “mighty mice” launched with double the muscle maintained their bulk. Their muscles appeared to be comparable to similar “mighty mice” that stayed behind at NASA’s Kennedy Space Center.In addition, eight normal mice that received “mighty mouse” treatment in space returned to Earth with dramatically bigger muscles. The treatment involves blocking a pair of proteins that typically limit muscle mass.A SpaceX capsule brought all 40 mice back in good condition, parachuting into the Pacific off the California coast in January. Some of the ordinary mice were injected with the “mighty mice” drug after returning and quickly built up more muscle than their untreated companions, Lee said.The scientists completed the experiment just as the coronavirus was hitting the U.S.“The only silver lining of COVID is that we had time to write it up very intensively” and submit the results for publication, said Dr. Emily Germain-Lee of Connecticut Children’s Medical Center, Lee’s wife who also took part in the study. Both are affiliated with the University of Connecticut.While encouraged by their findings, the couple said much more work needs to be done before testing the drug on people to build up muscle and bone, without serious side effects.“We’re years away. But that’s how everything is when you go from mouse to human studies,” Germain-Lee said.Lee said the experiment pointed out other molecules and signaling pathways worth investigating — “an embarrassment of riches ... so many things we’d like to pursue.” His next step: possibly sending more “mighty mice” to the space station for an even longer stay.Three NASA astronauts looked after the space mice, performing body scans and injections: Christina Koch and Jessica Meir, who performed the first all-female spacewalk last fall, and Andrew Morgan. They are listed as co-authors.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2835

California health officials are warning residents not to eat oysters from British Columbia, Canada, following a norovirus outbreak.About 100 people got sick in California after they consumed the raw oysters, health officials said."As of April 27, approximately 100 individuals have reported illness after they consumed raw British Columbian oysters sold by restaurants and retailers throughout the state," the California Department of Public Health said."Laboratory testing has confirmed norovirus infection in several patients from both California and Canada. Although the number of reported new illnesses has decreased during the last week, the investigation is ongoing."Canada has reported 172 cases of gastrointestinal illness linked to consumption of raw oysters."Avoid eating raw and undercooked shellfish, including oysters, to reduce your risk of illness," said Dr. Karen Smith, a public health officer in California."If you do eat shellfish, cook it until it reaches an internal temperature of at least 145°F. Quick steaming isn't sufficient to kill norovirus."Norovirus is spread through the ingestion of infectious virions, which grow in the small intestine before being expelled in feces. Infection usually occurs when someone eats food or drinks liquids that have been contaminated, touches surfaces or objects that are contaminated and then puts their hands in their mouth, or has contact with someone who has been infected, such as by sharing food.Norovirus causes inflammation of the stomach, the intestines or both. A person usually develops symptoms 12 to 48 hours after being exposed.Common symptoms include vomiting, diarrhea, nausea and stomach cramps.  1687

Charges have been dropped against the man accused of criminal homicide in the Opry Mills shooting.Chaos ensued when 22-year-old Justin Golson?shot at?22-year-old?Demarco Churchwell, who was taken to Skyline Medical Center in critical condition where he later died.Immediately after the shooting, Golson ran from the mall to a ticketing booth outside, placed his gun on the counter, and told the people inside to call 911. He told detectives he acted in self-defense after being threatened over social media by the victim and his friends.The mall was evacuated as police secured the area and investigated the incident.Court records show Golson's charge of criminal homicide was dismissed on Monday, July 30. 729

CARLSBAD, Calif., (KGTV) -- Nearly 200 active duty mothers and mothers who support active duty staff at Camp Pendleton, got a full day of pampering at the 12th Annual Military Mother's Day Brunch. 10News spoke to the Torres family. "Right now, Daddy's deployed," mother, Sonia Torres said. While her husband defends the country as Sgt. Major of Batallion 1-4, she defends the homefront as she cares for her two children, Jasmine and Al."My mom means the world to me. She does everything for me. Cook, kisses me good night, everything," 11-year-old Al said.With no family nearby, military mothers like Torres are in a unique parenting situation. They play the roles of both mom and dad. "Since Daddy left, we needed something to fill that void, and we found Tae Kwon Do. We [Al] went from white belt to yellow belt to orange belt, Friday night." Torres said proudly.They often witness milestones alone. Jasmine celebrated her 13th birthday yesterday. "My mom is well, there's no words to describe it. She's always there for me. I couldn't really ask more than that," Jasmine said. So they don't. The Torres children will spend the rest of their lives being Mama's Girl and Mama's Boy."When I'm in university or college, I would be really close to her because she's my number one fan," Al said. The event also helps connect mothers with resources and other people who understand the difficulties that come with being a military parent. 1442

CAMPO, Calif. (KGTV) - The U.S Border Patrol arrested in Campo Wednesday a Mexican citizen who they say had close to 10 pounds of cocaine in his car.Agents at the westbound Interstate 8 checkpoint referred a silver 2007 Volkswagen Jetta to a secondary inspection about 1:30 p.m.A Border Patrol K-9 sniffed the vehicle and uncovered the drug bundles. They were found in a modified compartment inside the dashboard, agents said.Four packages, weighing a total of 9.88 pounds, tested positive for cocaine and were valued at approximately ,800.The unidentified 25-year-old driver was arrested. Agents said he had a Border Crosser Card, which is available for citizens of Mexico who travel to the U.S.Border Patrol agents turned over the narcotics the Drug Enforcement Administration. 790