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2025-06-02 10:26:46
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WELLINGTON, June 7 (Xinhua) -- Scientists in New Zealand have developed a new drug to fight previously untreatable hypoxic cancer tumors, which form in areas of the body starved of oxygen.The researchers at the Auckland University have entered an agreement for the clinical development of CEN-209, which was developed over 10 years of research, said a statement from the university Tuesday.CEN-209 was designed to enhance the effectiveness of radiotherapy and chemotherapy in solid hypoxic tumors, which were resistant to standard cancer therapies, said the statement. In lung cancer patients for example, about half of tumors had hypoxic regions.The new drug worked by damaging the DNA of hypoxic cancer cells, while leaving normal, healthy tissues alone.CEN-209 was designed and created by researchers at the university's Auckland Cancer Society Research Centre (ACSRC), using computer models of drug transport within tumors to accurately predict the anti-tumor activity of the drugs."Our computer models of drug transport developed in-house allowed the synthetic chemists to test their design theories and considerably shortened the discovery process," said Associate Professor Michael Hay, who led the ACSRC research chemists."CEN-209 improves markedly on previous agents in this class in terms of its ability to penetrate tumors, and this is reflected by its improved activity in the laboratory, when combined with long or short courses of radiotherapy," said researcher Professor Bill Wilson.Under the agreement between the university's Auckland UniServices Ltd. and California-based Centella Therapeutics, Inc., a subsidiary of Varian Medical Systems, Inc., Centella will have exclusive rights to CEN-209, which it will develop and trial with Cancer Research UK.The work on CEN-209 is the culmination of a program initiated with funding from the U.S. National Cancer Institute, and more recently from the Maurice Wilkins Centre for Biodiscovery. Ongoing preclinical research on CEN-209 and a backup compound was funded by grants from the Auckland Medical Research Foundation, Genesis Oncology Trust and Health Research Council of New Zealand, said the statement.

  成都蛋蛋静脉曲张哪个医院治   

BEIJING, Aug. 14 (Xinhua) -- Gary Locke, the newest U.S. ambassador to China, promised on Sunday to promote bilateral cooperation and understanding between the two countries.Acknowledging challenges in the "important and complex diplomatic and economic bilateral relationship" between the two countries, Locke said he looks forward to working with the Chinese government to expand bilateral cooperation and collaboration.He made the remarks at a press conference held on Sunday afternoon, his first public appearance since arriving in Beijing on Friday evening. Locke's wife Mona Lee and their three children accompanied him at the conference.Speaking about the things he hopes to accomplish over the next several months, Locke said the most important thing will be "to promote stronger and better understanding between the U.S. and China.""This must be done so that more people in the United States understand China, its history, its contributions to world civilization, its challenges and the amazing progress China has made in such a short time," he said.Locke also stressed China's "unique history, culture, and philosophy," which he said must be understood if the two countries wish to forge a more cooperative relationship.Locke, a Democrat, was elected as Washington state's 21st governor in 1996, becoming the first Chinese-American governor in U.S. history. He won reelection in 2000. President Obama nominated Locke as Commerce Secretary in February 2009.

  成都蛋蛋静脉曲张哪个医院治   

COPENHAGEN, May 29 (Xinhua) -- The number of confirmed E.coli cases has risen to 11 with at least another eight persons suspected of having the intestinal infection in Denmark, according to Denmark's National Serum Institute on Sunday.Five of the confirmed cases show symptoms of kidney failure which marks an advanced stage of the sickness, the institute said.Danish cucumbers are suspected of helping spread the E. coli bacteria believed to be causing a deadly outbreak of intestinal infection in Denmark and Germany, local media reported Sunday.The Danish cucumbers were mixed in Germany with cucumbers originating in the Netherlands, making it difficult to determine if Danish cucumbers are in fact contaminated.Denmark's Veterinary and Food Administration (DVFA) had earlier said the suspicion against Danish cucumber was "vague", but advised Danish consumers not to eat raw tomatoes, lettuces and cucumbers from Germany, and cucumber from Spain.It is now checking Danish cucumbers for traces of E. coli with results expected on Tuesday.Some Danish retailers have now removed these products from their supermarket shelves. And the Danish branch of fast-food chain McDonald's announced Saturday that it was dropping fresh cucumbers from its menu until further notice.The infection, which is food-borne, can be caused by eating raw or uncooked foods such as vegetables contaminated with the E. coli bacteria.Symptoms of infection include mild fever, bloody diarrhea and vomiting, and can last five to seven days. It can prove fatal in the very young, sick, or elderly.

  

CANBERRA, Aug. 31 (Xinhua) -- Australia's new chief medical officer, Professor Chris Baggoley, on Wednesday said Australian should not be worried about reports that a mutant strain of the deadly bird flu virus is spreading across Asia and beyond.On Monday, the UN's Food and Agriculture Organization (FAO) said a mutant strain of the deadly avian influenza virus was spreading in Asia and issued a warning that the bird flu could spread from poultry to humans. It urged "heightened readiness and surveillance" as the mutant strain posed "unpredictable risks to human health."But Professor Baggoley, who took office on Tuesday, said Australia is well served by strict testing and customs regimes, adding that avian migration patterns also mean infected birds are highly unlikely to arrive in Australia."I don't think we should be worried," Prof Baggoley told Sky News."The country and the Australian government is certainly vigilant in relation to bird flu."Prof. Baggoley insisted the H5N1 virus remains overwhelmingly a disease of birds and it is very uncommon for humans to catch it. It is also exceedingly rare for humans to spread it among themselves.He said that even if bird flu did arrive and affected humans, Australia is ready to respond to any new and significant developments in bird flu."Australia tests migratory wild birds, looking for H5N1, and has been doing this for some years and has never found it," he said."On the human side of things, Australia has been preparing for a possible outbreak of H5N1 since 2004."We've got the laboratory capacity to diagnose influenza; we've got arrangements in place for a rapid production of an H5N1 vaccine for humans, and we've got ready access to antivirals."There have been no outbreaks of bird flu in Australia to date.The UN said the latest human death from bird flu occurred earlier this month in Cambodia, which has registered eight cases of human infection this year, all of them fatal.H5N1 has infected 565 people since it first appeared in 2003, killing 331.

  

SAN FRANCISCO, June 23 (Xinhua) -- Facebook announced Thursday that Netflix CEO and Chairman Reed Hastings has joined the social network company's board of directors.Hastings, who successfully managed Netflix through an IPO in 2002, is expected to provide useful guidance for Facebook which plans to go public.As the most popular subscription-based movie and television show rental service in the United States, Netflix could also help Facebook figure out how to enter the business of music streaming and movies, which, CEO Mark Zuckerberg said at the eG8 Forum held in Paris last month, would be Facebook's next focus.The Facebook board seat could also help Netflix to catch up with the social evolution of the Internet with its 23.6 million subscribers in the U.S. and Canada."Reed is an entrepreneur and technologist who has led Netflix to transform the way people watch movies and TV," said Zuckerberg in a statement. "He has built a culture of continuous rapid innovation, something we share and work hard to build every day.""Facebook is propelling a fundamental change in how people connect with each other and share all kinds of content," said Hastings. "I'm looking forward to working with Mark and the rest of the board to help Facebook take advantage of all the opportunities ahead."

来源:资阳报

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