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Pfizer announced Friday that it would submit a request to the FDA Friday for its COVID-19 vaccine to be granted Emergency Use Authorization.Earlier this week, Pfizer said that a final analysis of trial results showed the vaccine is 95% effective.“Our work to deliver a safe and effective vaccine has never been more urgent, as we continue to see an alarming rise in the number of cases of COVID-19 globally. Filing in the U.S. represents a critical milestone in our journey to deliver a COVID-19 vaccine to the world and we now have a more complete picture of both the efficacy and safety profile of our vaccine, giving us confidence in its potential,” Dr. Albert Bourla, Pfizer Chairman and CEO, said in a press release.Pfizer's two-shot vaccine has already been in mass production for months, and thousands of doses will be ready for delivery if and when the FDA grants authorization. Pfizer says that is on track to produce 50 million doses of the vaccine by the end of 2020 and plans to produce 1.3 billion doses of the vaccine in 2021.According to "Operation Warp Speed," the federal government's plan for distributing the vaccine, upon authorization, the drug will initially be rationed for high-risk populations and health care workers. Dr. Anthony Fauci, the nation's top infectious disease expert, says he believes a vaccine won't be widely available until April.On Wednesday, Pfizer announced that a final analysis of its vaccine candidate showed that of 40,000 participants who participated in the trial, 170 people had contracted the virus. Of those 170 people, 162 received only a placebo injection — meaning just eight out of the 20,000 people who actually received the vaccine contracted the virus.The company added Wednesday that there have been no safety concerns with the vaccine. In a randomized survey of 8,000 participants, only 2% reported suffering severe fatigue, and only 4% reported suffering severe headaches. Those who say they suffered side effects only experienced them briefly after vaccination.Pfizer's announcement comes as COVID-19 cases are spiking around the world. In the U.S. alone, about 2.5 million people have contracted the virus in the month of November alone. Hospitalizations linked to COVID-19 are at an all-time high, and deaths have begun to tick up in recent weeks. 2322

OXON HILL, Md. (AP) — The finals of the Scripps National Spelling Bee have begun, with 50 kids on stage competing for more than ,000 in cash and prizes and a new, custom-designed trophy.This year's bee had the biggest field ever, with 562 spellers, more than half of whom got in through Scripps' wild-card program. Last year was the first time that wild cards were allowed into the bee, and the eventual champion was a wild card.Thursday's finalists include nine spellers who finished in at least a tie for 10th last year. The field will be narrowed to about a dozen spellers in the morning and early afternoon before the prime-time finals on ESPN.The last 14 champions and 19 of the past 23 have been Indian-American. 729

Pence tested negative for Covid-19 this morning. Staff says the change is meant to prevent burnout given the @VP’s weekend schedule, travel plans next week and late-night arrival back in DC this evening. https://t.co/c7w9weVRic— Gabby Orr (@GabbyOrr_) October 8, 2020 275

PHOENIX (KNXV/KGTV) - A small plane that crashed on a Phoenix street Monday morning -- killing both passengers  -- was just sold from a pilot in Solana Beach.The victims have been identified as 54 year-old Theodore Rich and 49 year-old Elaine Carpenter. FAA officials said the aircraft involved is a single-engine, home-built Acroduster. The plane went down in the intersection of 7th St. and Deer Valley Dr., near an FBI field office, at around 6:50 a.m. local time.One eyewitness said he saw the plane go down. At first he thought it was aerobatics, but after seeing the plane heading straight for the ground, he knew something was wrong. Video from the scene showed emergency crews working around debris in the roadway near several damaged cars. Police told media on scene the vehicles had substantial damage but no one on the ground was hurt.10News reporter Lauren Davis talked to Avi Maltzman, the Solana Beach man who just sold the plane to Rich this weekend. Maltzman said he flew with Rich for several touch-and-goes and described Rich as an experienced pilot. Maltzman said Rich even called him from Arizona just to let him know he made it home safely. “He impressed me very well with his flight skills. He did good eight or nine landings. He was comfortable and I felt comfortable with him," said Maltzman.Maltzman said the plane was built by professionally in Santa Barbara in 1993. Maltzman bought the plane in 2011 and said it was in great condition. Those who knew Rich said flying was his passion. They said Rich died doing what he loved.    1614

Police in southwest England say two people are in critical condition and are being treated "for suspected exposure to an unknown substance." One of the victims is a former Russian spy, Britain's national broadcaster said."The two people -- a man aged in his 60s, and a woman aged in her 30s -- were found unconscious on a bench in The Maltings in Salisbury," Wiltshire police said on Monday, adding that the injured are known to each other.UK's national broadcaster, the BBC, is naming the man, who is in his 60s, as former Russian spy Sergei Skripal, who was granted refuge in the UK following a "spy swap" between the US and Russia in 2010.None of the individuals involved has been named by the UK Home Office, Wiltshire Police or Salisbury Hospital."Because we are still at the very early stages of the investigation, we are unable to ascertain whether or not a crime has taken place," police said.Reiterating an earlier announcement, police said in a statement on Monday that "a major incident has been declared today and a multi-agency response has been co-ordinated." 1081

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