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SAN DIEGO — San Diegans can participate in AstraZeneca's COVID-19 vaccine trial, which recently showed 90 percent effectiveness under a certain dosage.AstraZeneca announced Monday that its vaccine was 90 percent effective when participants started with a half dose, followed by a full dose at least four weeks later. It is currently seeking participants through UC San Diego Health and other partners for its ongoing trials. Full doses given four weeks apart were 62 percent effective in the trial. “These findings show that we have an effective vaccine that will save many lives," said Professor Andrew Pollard, Chief Investigator of the Oxford Vaccine Trial, in a statement released by AstraZeneca. "Excitingly, we’ve found that one of our dosing regimens may be around 90 percent effective and if this dosing regime is used, more people could be vaccinated with planned vaccine supply."Elana Godebu, a UC San Diego urologist, said she has seen the impacts of Coronavirus firsthand. She is currently practicing at El Centro Regional Medical Center, affiliated with UC San Diego. She says the center is filling up because of a rise in local cases and patients coming up from Mexico. The state recently built a 50-bed tent in the parking lot for non-Covid patients. Godebu got the first dose of the vaccine two weeks ago, which also could have been a placebo."Personally I've seen my friends and my colleagues and my patients, they've gotten sick, they've lost family, they've lost friends, and so we got the AstraZenica trial out in El Centro," she said. Godebu said she encourages anyone who has an opportunity to get the vaccine to take advantage. "If we try to get to herd immunity the other way we're going to lose so many people," she said. AstraZenica is the latest drugmaker to report strong efficacy. Earlier this month, Pfizer and Moderna said their trials were 95 percent effective. AstraZenica says its vaccine could separate from the others because it can be transported, handled and stored at regular refrigerated temperatures and administered in regular health care settings. 2099

SALEM, Ore. (AP) — The death toll from the wildfires raging on the West Coast stands at least 33, with authorities saying nearly all of the dozens of people reported missing after a devastating blaze in southern Oregon have been accounted for. The flames have destroyed neighborhoods, leaving a barren, gray landscape in their wake, driven tens of thousands of people from their homes and cast a shroud of smoke over the region. The crisis has come amid the coronavirus outbreak, the economic downturn and nationwide racial unrest that has led to protests in Portland for more than 100 days. 599

Sales are surging at Stoddard’s Range and Guns. Long lines pack the Atlanta shooting range with people buying guns and ammunition.Co-owner Ken Baye says sales have soared since mid-March, when the pandemic hit.Now, he’s seeing a second wave of interest with more people now looking to learn how to use a firearm.That includes people like Michelle DeShields, an elementary school counselor. She's aiming to increase her personal safety during these uncertain times.“It’s just been scary with police brutality that we are looking at, even the protesting sometimes, you see it’s gotten a little out of hand,” she said.The National Shooting Sports Foundation reports background checks for firearms purchases saw record highs in April and May.And that millions of those people are new gun owners.DeShields' father was a military veteran and a police officer. So, she grew up with guns but never learned to use one until now.“I do feel like guns used safely for protection and they are a good thing,” she said.Though, her gun is something she hopes to never have to use outside of a shooting range. 1100

SAN DIEGO (CNS) - A COVID-19 vaccine trial sponsored by drugmaker Johnson & Johnson is slated to get underway soon in San Diego, and will include an estimated 2,000 participants at UC San Diego Health, it was announced Thursday.Up to 60,000 participants will be recruited from 10 different countries around the world as the San Diego portion of the trial, dubbed ENSEMBLE, gets underway Oct. 7, according to UCSD.The efficacy, safety and immunogenicity of the drug Ad.26-COV2.S will be tested via a randomized, double-blind, placebo-controlled study, in which half of the participants receive a single-dose injection of the vaccine and the other half receive a placebo. All participants -- who must be 18 years of age or older and in reasonably good health -- will be monitored for signs of infection and COVID-19 over the next two years, according to UCSD.Researchers are particularly interested in recruiting participants at increased risk of SARS-CoV-2 infection due to where they live, their age or personal circumstances, such as working in essential jobs like first responders, health care, maintenance, construction, grocery stores or assisted living facilities.The San Diego trial will also emphasize participation from the region's underserved communities, as communities of color have shown higher rates of COVID-19-related hospitalization and/or death.UCSD cited data from the county showing measurably higher infection rates in the South Bay, including in Chula Vista, Imperial Beach and National City.Susan Little, professor of medicine at UC San Diego School of Medicine and principal investigator of the UC San Diego trial, said, "Many communities of color are experiencing higher rates of hospitalization related to COVID-19 than are observed in white, non-Hispanic people. It is important that these communities are represented in COVID-19 vaccine clinical trials so that we understand if the vaccine will work well within these groups."For more information about participating in the trial at UC San Diego, go to www.covidvaccinesd.com or call 619-742-0433. 2087

SAN DIEGO — Three teenagers were taken into custody in three separate attempts to smuggle fentanyl across the U.S.-Mexico border, according to federal officials.U.S. Customs and Border Protection (CBP) said the incidents occurred on March 30 and 31 at the San Ysidro Port of Entry near San Diego, California.On Friday, CBP agents stopped a 17-year-old Mexican citizen. After noticing an "anomaly" on the teen's back, agents conducted a pat down and found two packages strapped to his back. The packages contained four pounds of fentanyl — a street value of 1,000.The next day, CBP agents stopped two more male teens within 10 minutes of each other: a 17-year-old and a 15-year-old. Both were found to have packages of fentanyl strapped to their backs. The two combined were carrying about nine pounds of drugs, a street value of more than 6,000.The teens in each case were arrested and turned over to Homeland Security Investigations. The all drugs were seized by CBP officers.According to Pete Flores, the director of Field Operations for Customs and Border Protection in San Diego, Fentanyl is 50 to 100 times more deadly than heroin."Please understand that no matter what you may be told, there are consequences for engaging in this type of activity, not to mention the dangers of working with transnational criminal organizations,” he said, 1383