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ORANGE, Calif. - As Amtrak prepares for the busiest travel period of the year, the company is adding railcars and requiring reservations for passengers. Due to increased crowds for holiday travel, Amtrak is encouraging passengers to plan ahead and book early. Reservations will be mandatory between Wednesday, Nov. 27 and Monday, Dec. 2. Metrolink and COASTER passes will not be accepted onboard Pacific Surfliner trains during this time, however Amtrak monthly and 10-ride passes may still be used. Additionally, the Rail 2 Rail program will be suspended during these dates. The Pacific Surfliner route travels between San Diego, Orange County, Los Angeles, Ventura, Santa Barbara, and San Luis Obispo. It offers a total of 26 trains a day between Los Angeles and San Diego. All Pacific Surfliner trains feature reclining seats, power outlets, Wi-Fi, bike and luggage racks, and a cafe that offers food and drinks, including alcoholic beverages. Coach tickets guarantee a space on the train while Business class passengers are guaranteed a seat. Tickets and reservations are available on PacificSurfliner.com, Amtrak.com, Amtrak mobile apps, or by calling 800-USA-RAIL. 1179
Officials with Operation Warp Speed confirmed Wednesday that they remain on track in their goal to distribute 20 million initial doses of COVID-19 vaccines by the end of the month.Health and Human Services Sec. Alex Azar, as well as Operation Warp Speed chief medical adviser Dr. Moncef Slaoui and the operation's chief operating officer Gen. Gus F. Perna, said Wednesday that the first shipments of Pfizer's COVID-19 vaccine were delivered largely without issue.The briefing comes just two days after medical centers across the country began administering the first initial doses of a COVID-19 vaccine made by Pfizer. That vaccine was approved for Emergency Use Authorization by the FDA last Friday and was formally recommended by the Centers for Disease Control and Prevention over the weekend.The briefing also comes a day before a vote by an FDA panel on whether to recommend a COVID-19 vaccine produced by Moderna for Emergency Use Authorization. Should the panel vote in favor of the recommendation, it would keep the Moderna vaccine on track for authorization by next week.In a report released Tuesday, the FDA reaffirmed Moderna's safety and efficacy statistics that were published following the conclusion of the drug's Phase III trial. Slaoui also said that a vaccine candidate produced by Johnson & Johnson is slated to fill its Phase III trials by tomorrow, and that initial efficacy data for that drug would be available by early January. He added that initial results of a vaccine candidate produced by AstraZeneca could be available later in January.Azar also said Wednesday that though supplies remain limited, there are still some therapeutic drugs, like antibody treatments, available for high-risk COVID-19 in some areas. Azar encouraged any high-risk patients who have been diagnosed with the virus to ask their healthcare provider about the availability of the drugs. 1900
One COVID-19 vaccine in development may be ready for review in December.Executives at Novavax say they are enrolling volunteers for a second phase of clinical trials now. The data should be ready for review within a few months.Phase 1 data showed the two-dose vaccine in healthy adults produced antibodies in all participants. Tenderness and pain were the most frequent local symptoms.When the first COVID-19 vaccines are approved, we won't know a whole lot about their safety.“We’re going to learn as we go along. There are numerous case studies in our experience where, as vaccines were rolled out, we were quite confident with the safety profile, but that evolves,” said Dr. Jon Andrus, adjunct professor at George Washington University’s Milken Institute School of Public Health.“I think that these vaccines will be safe in the sense that they won’t cause a serious or permanent adverse event when tested in 10,000, 15,000, 20,000people,” said Dr. Paul A. Offit with the Children’s Hospital of Philadelphia. “Hopefully, that will also be true in post approval when it’s tested and seen in 20 million, 30 million people.”Based on other vaccine history, a COVID-19 vaccine will likely produce some sort of adverse reaction. It could be minor typical injection site issues or something more serious.Back in the 1950s, the very first massive polio vaccination program was stopped because it paralyzed some children and killed a handful.In the 70s, the swine flu vaccine caused a very small amount of rare neurological cases. There are other issues like an allergic reaction or seizure.Still though, experts say vaccines are one of the greatest advances in modern medicine in preventing unnecessary deaths.“There is no better cost-effective intervention that medical science has to offer with the exception of safe water and sanitation, so when you look at our life expectancy, vaccines have been incredibly important,” said Andrus.The Vaccine Injury Litigation Clinic handles cases of vaccine-related injuries and deaths. They have on average just over 600 people per year receive payouts from the National Vaccine Injury Compensation Program. But they admit vaccine injuries are still rare compared to the overall numbers of administered vaccines every year.The Centers for Disease Control and Prevention (CDC) says for every 1 million doses of vaccines that were distributed, one person was compensated. 2413
Of all the campaign slogans for 2020, Allison Ali is following motherly advice from her childhood.“My Mama always said, ‘if you don’t vote, you don’t have a voice,’” she said. “So, it’s put up or shut up.”Ali is taking those wise words on the road and also taking voters to the polls for free.“It’s important to me, because everybody needs to be heard,” she said.This election season, Ali is one of hundreds of people working for the Neighborhood Assistance Corporation of America during a campaign called “Roll to the Polls.”“We have a real opportunity to impact the elections,” said NACA CEO Bruce Marks.Marks’ team has 100 vans in Atlanta and 50 more in Houston with a goal of getting 100,000 voters from their houses to their polling locations free of charge.“It is very emotional because we’ve been through a lot,” Marks said of these free rides. “We’ve seen the voter suppression and we’ve seen how people’s rights are taken away. So, it’s crucial that everybody’s voice is heard.”Across the country, rideshare apps, colleges and even some concerned citizens are offering voters free rides to the election sites.While some political science experts warn that free rides could be used as a way to manipulate voters, others are calling it a sign of inspiration.“I want to do my part, honestly, to get them out,” said Atlanta-based voter Pamela Chaney, a self-described vibrant senior.Chaney says this election is the most crucial of her lifetime and that’s why she’s now thinking about volunteering to drive voters to polls, especially those in her community, where public transportation isn’t an option.“A lot of people probably want to come out, but they don’t have the means; transportation. They’re probably elderly,” she said.According to the American Association of Retired People, 71% of Americans over the age of 65 voted during the last presidential election, a group Ali hopes to steer clear from any of kind of voter suppression.“We have people who think their votes aren’t going to count,” she said. “They don’t think the mail is going to get their in time. That’s a scary thing.”While behind the wheel, Ali is still following her mother’s advice and driving down a road that others helped pave the way.“We have ancestors that fought for us to be able to come out here and vote,” she said. “This election for me is very important.” 2355
Oklahoma and Kentucky teachers are walking off the job Monday and holding rallies in their state capitols to pressure lawmakers.Inspired by the West Virginia strike in which teachers demanded and got a pay raise from state leaders, a wave of other states including Oklahoma, Kentucky and Arizona are taking similar action. Educators are organizing and publicly pressuring state lawmakers over issues like education funding, teacher salaries and pension reform.Teachers in Oklahoma are rallying for more education funding and salaries, and those in Kentucky will be marching over a controversial pension bill and the state budget. 637