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WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.

BEIJING, June 11 (Xinhua) -- The Baidu Charitable Foundation (The Baidu Foundation) and The Bill & Melinda Gates Foundation (The Gates Foundation) founded a strategic charitable alliance here Saturday, in a bid to work for a healthy, smoke-free environment both in China and around the world.Li Yanhong, president of Baidu company, China's top online search engine operator, and Bill Gates, co-chair and trustee of the foundation under the names of the couple, attending the ceremony, both wore a shirt that said, "Say No to Forced Smoking."In his speech at the ceremony, Bill Gates said, "This will be a long-term, open-ended alliance. As a sponsor, Mr. Li and I would like to welcome more partners, and we expect to see more Chinese enterprises and all facets of society to focus on public health issues together."Li Yanhong also addressed the meeting, claiming, "Living healthy and green has become a common pursuit of mankind. We hope the alliance can bring together public efforts for this global cause, so that more people can benefit from our endeavor." ' The alliance's first action is to comply with the government ban on smoking in public places and refuse forced smoking, according to a press release from the foundations.Targeting "forced smokers," the alliance will carry out educational campaign through all channels of media to educate and promote self-awareness about the dangers of forced smoking. Moreover, it will also help existing smokers, especially those who are underage, by sharing scientific methods for quitting.Smoking is one of the world's eight primary causes of death, leading to lung disease, cancer, heart disease, low birth rate, fetal death, tuberculosis, high mortality and many other health issues. Smoking forces many families into poverty by causing both poor health and premature death.China ranks first in tobacco consumption and production in the world. China has 300 million smokers, and one in every three cigarettes smoked in the world is smoked in China. More than half of Chinese smokers are male; and more than 1 million people die from smoking related diseases each year.In addition, China has 740 million "forced smokers," whose health also suffers. The World Health Organization (WHO) notes that there is no safe level of second-hand smoke.This year, China published its 12th Five-Year Plan (2011-2015) that clearly stipulates for "implementing a full-scale ban on smoking in public facilities." This is the first time that tobacco control has been included as part of China's five-year plan for national economic and social development."Rules for Implementation of Public Facilities Health Management Regulations," effective since May 1st, also specifies to "ban smoking at all public indoor facilities," providing legal basis for non-smokers to protect their rights of health and to refuse "involuntary smoking."Aside from tobacco control, the strategic alliance co-founded by the foundations will also collaborate on a series of projects, such as AIDS prevention and control, in a joint effort to promote health for mankind.Founded in 2000, the Gates Foundation currently carries out charity projects in over 100 countries. Since establishing the Beijing Representative Office in 2007, the Gates Foundation has supported a range of health and development projects in China, including the advocacy of smoke-free environment, AIDS and tuberculosis prevention and control, and agricultural development and research projects.Launched in 2010, the Baidu Foundation is committed to use information technology for support of youth and disadvantaged groups, focus on the environment and promote social harmony.Ever since Baidu was founded, Li has actively pushed for tobacco control within the enterprise and the industry. He is the only Chinese member of the United Nation AIDS Prevention Senior Committee and also board member of the HuaXia Charity Foundation.

ULAN BATOR, Aug. 2 (Xinhua) -- The Mongolian government has confirmed equine influenza, a disease that mainly affects horses, broke out in 14 provinces.The government's news office announced the confirmation Tuesday after suspected cases were recently discovered in 18 provinces of the country, where horses still play a key role.According to a Mongolian government report, Mongolian Vice Premier M. Enkhbold called a state emergency situation committee meeting on Monday to respond to the epidemic.Millions of horses will need to be vaccinated, given cases of the disease have been discovered in all but three provinces -- Bayan-Ulgii, Zavkhan and Umnugobi.Equine influenza usually broke out in spring and fall, said an official of the Mongolian veterinarian and breeding bureau. He urged vaccination to be carried out as soon as possible.Mongolia has experienced several equine influenza outbreaks in the past few decades. Outbreaks in Khovd province in 2007 and 2008 caused huge losses to the local livestock industry.Animal husbandry is a dominant factor in the agriculture sector of Mongolia, which has more than 40 million livestock, 2 million of which are horses.

CANBERRA, Aug. 29 (Xinhua) -- Alzheimer Australia on Monday released a GPS device for people with dementia, in a move to give them greater independence, while reducing the burden of missing person searches for police.The technology has been using in New South Wales of Australia, and is now available for people in state Victoria.The Safe2Walk locater can be worn by people with dementia on a lanyard around the neck or clipped onto a belt. Families can log- on to the connected website and see where the person is.The device updates the person's location every 60 seconds, reducing stress for carers so they know when a person with dementia might be wandering.It also works as a mobile phone, letting the person wearing the device to make instant calls to family.According to Alzheimer's Australia's research manager Jason Burton, the device aimed to stop vulnerable people getting lost, with research showing about 40 percent of people with dementia went missing at least once."In 99 percent of cases the carer has gone to pick them up, but there was one case where they couldn't and the police were able to contact us to get the exact GPS location of this person to rescue them," Burton told Herald Sun.A Victoria Police spokeswoman said while it could not endorse a specific product, if the device could alert carers when a person with dementia first became disorientated, the response could help avoid a large-scale police search.Mina Sapounakis, who's father has worn the Safe2Walk device, said it has given her family a sense of calm."We could go grocery shopping without stressing and rushing back home quickly to check on Dad," she said."There were a few times he had gone wandering and we were able to easily find him without having to call the police."The Safe2Walk GPS costs under 15 U.S. dollars a week for rent.

HELSINKI, July 4 (Xinhua) -- A new Finnish research shows that sleeplessness may be hereditary, and insomniacs are more likely to die earlier than people with healthy sleep patterns.The research is the first to link insomnia with mortality risk, Finnish media reported on Monday.The research is conducted by the Institute of Occupational Health in collaboration with the University of Helsinki and the Finnish National Institute for Health and WelfareIn a large-scale twin study, the Finnish researchers followed the health status of 12,500 adult twin pairs during the years from 1990 to 2009. Twenty percent of the participants were suffering from sleeplessness symptoms, including difficulty in initiating sleep, nocturnal awakening and non-restorative sleep.The study found out that compared with unidentical twins, identical twins were more likely to suffer from similar insomnia symptoms. This finding indicates that genetic factors play a role in the formation of insomnia.Moreover, the participants were divided into three groups, according to their sleep qualities. Out of the participants, 48 percent were good sleepers, 40 percent average sleepers and 12 percent poor sleepers. The search result shows that insomnia-related symptoms may increase mortality risk.In addition, compared with good sleepers, 7 percent of the women and 22 percent of the men who were average sleepers were more likely to die earlier; and poor sleepers were 1.5 times more likely to die earlier.According to the researchers, sleeplessness is a common health problem among working-age cohort. Chronic sleeplessness raises the risk of many illnesses and accidents, and thus weakens people's quality of life and ability to operate properly.The experts suggest that insomniacs should seek medical treatment in time, and chronic insomnia patients should be better treated with non-drug therapy.