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BEIJING, March 5 (Xinhua) -- China's retailers will offer refund to recent buyers of iPad 1 as price dropped with the debut of iPad 2.Apple released the upgraded version of the tablet on March 3 and announced to lower the price tags of the first generation iPad 1 by up to 27.6 percent. Buyers of iPad 1 within the last two weeks are eligible for a price difference compensation, according to Apple.Chinese customers who bought the product via Apple China online or its chain stores will also be compensated, according to a statement on Apple's website.Chinese electronics retailers such as Suning and Gome responded quickly to the price cut, promising to pay back their customers with a refund.Suning, China's biggest electronics retailer by market value, said iPad 1 buyers who bought the product from Feb 17 to March 2 can get the refund with the receipt starting Saturday.Gome, the second largest electronics retailer in China, also announced to pay back their customers who bought the product from Feb 18 to March 3 from their stores. Customers could apply for the refund with the receipt starting Sunday.

WASHINGTON, April 4 (Xinhua) -- Scientists have identified a gene that appears to play a role in regulating how much alcohol people drink, in a study of over 47,000 people published Monday in the Proceedings of the National Academy of Sciences.The researchers say that finding a common genetic variation influencing levels of alcohol consumption may lead to a better understanding of mechanisms underlying alcohol drinking behavior in the general population.The gene, called "autism susceptibility candidate 2", or AUTS2, has previously been linked to autism and attention deficit hyperactivity disorder, but its function is not known.The new study, by an international consortium led by scientists at Imperial College London and King's College London, found that there are two versions of the AUTS2 gene, one three times more common than the other. People with the less common version drink on average five percent less alcohol than people with the more common version.The gene is most active in parts of the brain associated with neuropsychological reward mechanisms, suggesting that it might play a part in regulating the positive reinforcement that people feel when they drink alcohol.Alcohol consumption is known to be partly determined by genes but until now the only gene known to make a notable contribution was the gene encoding alcohol dehydrogenase, an enzyme that breaks down alcohol in the liver.Professor Paul Elliott, from the School of Public Health at Imperial College London, said: "Of course there are a lot of factors that affect how much alcohol a person drinks, but we know from twin studies that genes play an important role. The difference that this particular gene makes is only small, but by finding it we've opened up a new area of research into the biological mechanisms that control drinking."

WASHINGTON, April 6 (Xinhua) -- A study led by researchers at the University of Michigan (U-M) showed in animal studies that new cancer drug compounds they developed shrank tumors, with few side effects.The study, done in two mouse models of human cancer, looked at two compounds designed to activate a protein that kills cancer cells. The protein, p53, is inactivated in a significant number of human cancers. In some cases, it is because another protein, MDM2, binds to p53 and blocks its tumor suppresser function. This allows the tumor to grow unchecked. The new compounds block MDM2 from binding to p53, consequently activating p53."For the first time, we showed that activation of p53 by our highly potent and optimized MDM2 inhibitors can achieve complete tumor regression in a mouse model of human cancer," says lead study author Shaomeng Wang, director of the Cancer Drug Discovery Program at the U-M Comprehensive Cancer Center.Wang presented the study Wednesday at the American Association for Cancer Research 102nd annual meeting.Many traditional cancer drugs also activate p53 but they do so by causing DNA damage in both tumor cells and normal cells, causing side effects. These new MDM2 inhibitors activate p53 while avoiding the DNA damage common with other drugs. In this study, which was done in collaboration with Ascenta Therapeutics and Sanonfi-Aventis, researchers showed that these new drugs shrank tumors without significant side effects.Because p53 is involved in all types of human cancer, the new drug has potential to be used in multiple types of cancer. Further, the researchers also identified certain markers in tumors that predict which ones will be particularly sensitive to the MDM2 inhibitor, which would allow physicians to target the drug only to patients most likely to benefit.

SAN FRANCISCO, April 22 (Xinhua) - Amazon's web-services disruption issues have not been completely resolved Friday morning, as some websites still in slow recovery.Amazon said in an update early Friday that meaningful progress has been made and is expected to continue over the next few hours.Reddit, a social news website, said on its homepage that "we are slowly getting our capacity back," and users may be able to log in if lucky. Some sites appeared to have recovered, including location-based social networking site Foursquare and HootSuite, an online brand management and social websites monitoring service.Amazon has not released the number of companies which have been disrupted by the outage and when the web-services will fully recover.The outage highlights risks of relying on public cloud service. Security and reliability have been experts' concerns on public could web-hosting service. Many Internet startups have been relying on the service to bring their costs down.Elastic Compute Cloud (EC2) is a central part of Amazon's cloud computing platform Amazon Web Services. It allows users to rent virtual computers on which to run their own computer applications. The European Space Agency, PBS and Ericsson are all among its cloud service customers.According to Amazon's Service Health Dashboard, errors began at 1:41 a.m. PDT Thursday in its datacenter in northern Virginia, saying "instance connectivity, latency and error rates."

BEIJING, April 12 (Xinhuanet) -- The elderly have a difficult time with multi-tasking as a study suggests that older brains behave differently when it comes to switching between two tasks, according to media reports on Tuesday.Researchers used functional magnetic resonance imaging (FMRI) to analyze brain activity in 20 people over age 60 by asking them to contemplate outdoor photos shown briefly. Then the elderly were presented with the picture of a face and asked to determine its gender and age, before being asked to recall details from the original scene they viewed.Researchers then compared their results to a similar experiment with 20 younger adults and found the brains of older subjects were less capable of disengaging from the interruption and reestablishing the neural connections necessary to switch back to focusing on the original memory."Unlike younger individuals, older adults failed to both disengage from the interruption and re-establish functional connections associated with the disrupted memory network," write Wesley C. Clapp of the University of California, San Francisco, and colleagues in the Proceedings of the National Academy of Sciences.The study, published in the online edition of the journal Proceedings of the National Academy of Sciences, sheds new lights into a growing body of studies showing that one's ability to move from one task to another in quick succession becomes more difficult with age.