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BEIJING, August 1 (Xinhuanet) -- U.S. researchers have discovered a genetic mutation unique to African Americans that links to heighten their asthma risk, according to reports published on Sunday in the journal Nature Genetics.Researchers of University of Chicago found a gene, PYHIN1, and its variations may account for asthma risk in people of African descent. In their study, they examined data from nine previous genome-wide association studies, totaling more than 2 million single nucleotide polymorphisms in 3,246 asthma patients and 3,385 control patient, 1,702 patient-parent groupings, 355 family-based cases, and 468 family-based controls.In the study, the researchers found that between 26 percent and 29 percent of people of African-descent carried at least one copy of the gene.  In particular, one polymorphism of the gene was 34 percent more likely found in African-American and Afro-Caribbean people with asthma.  More interestingly, this variant of the gene is rarely found in Caucasian people and in Latino population, it was found in less than 5 percent.This new variant is part of a family of genes linked with the body's response to viral infections. It is thought to be involved in interferon signaling, which could influence the occurrence of asthma.The team stressed that each gene variant on its own plays only a small role in increasing asthma risk, but that risk could be multiplied when combined with other risk genes and with environmental factors.

WASHINGTON, Aug. 10 (Xinhua) -- After a journey of almost three years, NASA's Mars rover Opportunity has reached the Red Planet's Endeavour crater to study rocks never seen before, the U.S. National Aeronautics and Space Administration (NASA) announced on Wednesday.Scientists hope it will find rocks and terrain much older than any other that the itinerant robot has examined during its seven years on the red planet.The U.S. space agency said that Opportunity arrived at the rim of Endeavour on Tuesday. The golf cart-size rover is expected to remain at the 22-kilometer-wide crater for the next few years.A portion of the west rim of Endeavour crater sweeps southward in this color view from NASA's Mars Exploration Rover Opportunity."NASA is continuing to write remarkable chapters in our nation' s story of exploration with discoveries on Mars and trips to an array of challenging new destinations," NASA Administrator Charles Bolden said in a statement. "Opportunity's findings and data ... will play a key role in making possible future human missions to Mars and other places where humans have not yet been."NASA's Mars Reconnaissance Orbiter, which has been circling the planet since late 2005, detected clay minerals that form in wet conditions in the crater. Scientists want to find out if the minerals date back to Mars' distant past, when the planet is believed to have been wetter and warmer than the dry frozen desert it is today."We're soon going to get the opportunity to sample a rock type the rovers haven't seen yet," said Matthew Golombek, Mars Exploration Rover science team member, at NASA's Jet Propulsion Laboratory in Pasadena, Calif. "Clay minerals form in wet conditions so we may learn about a potentially habitable environment that appears to have been very different from those responsible for the rocks comprising the plains."NASA is searching for signs that Mars had a habitable environment billions of years ago. Knowledge of the Martian climate will be important to future manned missions there, and can shed light on the forces that shaped Earth's climate.NASA launched the Mars rovers Opportunity and Spirit in 2003 for what were planned to be three-month missions. But both continued operating well beyond that. Spirit stopped communicating in March 2010.

CANBERRA, Sept. 7 (Xinhua) -- A team of Australian and U.S. scientists on Wednesday said they discovered a genetic defect, which can lead to Leigh syndrome, a rare disorder which affects the central nervous syndrome.The scientists tested more than 1000 genes by encoding proteins active in two individuals who suffer from the illness. They used a new technique known as next-generation DNA sequencing to examine the genes.The gene they discovered encodes an enzyme which is found in the mitochondria which are subsets of cells. Without this enzyme the mitochondria do not translate proteins efficiently, and this then causes Leigh syndrome.According to David Thorburn, from the Murdoch Children's Research Institute in Melbourne, the discovery shows the enormous potential of the new technology."These findings demonstrate the ability of sequencing technologies to improve diagnosis," Professor Thorburn said in a statement released on Wednesday."Although it isn't clear in the case of Leigh syndrome whether the precise molecular diagnosis will necessarily lead to therapies, the current findings represent a meaningful service."He added that diagnosis of the disease along with its specific genetic cause can also be informative about the risk a couple has of having another affected child. The diagnostic information can help in decisions about whether and how to pursue alternative means of having children, for instance through the use of donor sperm or eggs.The research team consisted of scientists from Australia's Murdoch Institute as well as the Broad Institute in the U.S.In Leigh syndrome, infants are born apparently healthy only to develop movement and breathing disorders that worsen over time, often leading to death by the age of three. The problem is that the mitochondria responsible for powering their cells cannot keep up with the demand for energy in their developing brains.

WASHINGTON, June 21 (Xinhua) -- A new study from Harvard School of Public Health (HSPH) and University of California, San Francisco, researchers suggests that men with prostate cancer who smoke increase their risk of prostate cancer recurrence and of dying from the disease. The study will be published Wednesday in the Journal of the American Medical Association."In our study, we found similar results for both prostate cancer recurrence and prostate cancer mortality," said Stacey Kenfield, lead author and a research associate in the HSPH Department of Epidemiology. "These data taken together provide further support that smoking may increase risk of prostate cancer progression."Kenfield and her colleagues conducted a prospective observational study of 5,366 men diagnosed with prostate cancer between 1986 and 2006 in the Health Professionals Follow-Up Study. The researchers documented 1,630 deaths, 524 (32 percent) due to prostate cancer, 416 (26 percent) due to cardiovascular disease, and 878 prostate cancer recurrences.The researchers found that men with prostate cancer who were current smokers had a 61 percent increased risk of dying from prostate cancer, and a 61 percent higher risk of recurrence compared with men who never smoked. Smoking was associated with a more aggressive disease at diagnosis, defined as a higher clinical stage or Gleason grade (a measure of prostate cancer severity). However, among men with non-metastatic disease at diagnosis, current smokers had an 80 percent increased risk of dying from prostate cancer.Compared with current smokers, men with prostate cancer who had quit smoking for 10 or more years, or who had quit for less than 10 years but smoked less than 20 pack-years before diagnosis, had prostate cancer mortality risk similar to men who had never smoked. Men who had quit smoking for less than 10 years and had smoked 20 or more pack-years had risks similar to current smokers."These data are exciting because there are few known ways for a man to reduce his risk of dying from prostate cancer," said senior author Edward Giovannucci, professor of nutrition and epidemiology at HSPH. "For smokers, quitting can impact their risk of dying from prostate cancer. This is another reason to not smoke."Prostate cancer is the most frequently diagnosed form of cancer diagnosed in the United States and the second leading cause of cancer death among U.S. men, affecting one in six men during their lifetime. More than two million men in the U.S. and 16 million men worldwide are prostate cancer survivors.

SAN FRANCISCO, June 17 (Xinhua) -- A new research released on Friday shows that smartphone users in the United States are consuming more data than ever, growing by 89 percent in the first quarter on a year-over-year basis.According to data from marketing company Nielsen, the amount of data the average smartphone user consumes per month is 435 Megabytes (MB) in the first quarter of 2011, compared with 230 MB in the same period last year.As for the distribution of data consumption, data usage for the top 10 percent of smartphone users is up 109 percent while the top 1 percent has grown their usage by 155 percent from 1.8 Gigabytes (GB) in the first quarter of 2010 to over 4.6 GB this year.The research said consumers with iPhones and Android smartphones consume the most data, which is driven by app-friendly operating systems like Apple's iOS and Google's Android. Windows Phone 7 users doubled their usage over the fourth quarter of 2010 and the first quarter of 2011, perhaps due to growth in the number of applications available.Meanwhile, the cost per MB for smartphones has dropped by 46 percent over the last year, from 14 cents per MB to 8 cents, said the research.According to Internet marketing research company comScore, in the first quarter of 2011, 234 million Americans ages 13 and older used mobile devices, 74,6 million of whom are smartphone users.

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