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WASHINGTON, Oct. 9 (Xinhua) -- U.S. researchers have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions. In their report receiving early online publication Sunday in Nature Biotechnology, researchers describe using small interfering RNA technology to silence the biochemical signals that attract a particular group of inflammatory cells to areas of tissue damage."The white blood cells known as monocytes play a critical role in the early stages of the immune response," says Matthias Nahrendorf, of the Massachusetts General Hospital (MGH) Center for Systems Biology, the paper's senior author. "We now know there are two subsets of monocytes -- an inflammatory subset that defends against pathogens and a reparative subset that supports healing. But if the inflammatory response is excessive, it can block the healing process and exacerbate conditions such as heart disease and cancer."Cells damaged by injury or disease release a cocktail of chemicals called cytokines that attract immune cells to the site of the damage. Inflammatory monocytes are guided to sites of tissue injury by a receptor protein called CCR2, and the MGH-led team devised a strategy targeting that molecule to block the inflammatory process but not the action of the reparative monocytes.Small interfering RNA (siRNA) technology prevents production of specific proteins by binding to associated messenger RNA molecules and preventing their translation. However, the technique requires extreme precision in developing the right siRNA molecule and delivering it to the correct cellular location.To make sure that their siRNA preparation targeted the right monocytes, researchers first confirmed that its use reduced levels of CCR2 in monocytes and increased levels of the fragments produced when siRNA binds to its target. They then showed that monocytes from mice treated with the siRNA preparation were unable to migrate towards CCR2's usual molecular target. Experiments in animal models of several important diseases showed that the siRNA preparation reduced the amount of cardiac muscle damaged by a heart attack, reduced the size and the number of inflammatory cells in atherosclerotic plaques and in lymphomas, and improved the survival of transplanted pancreatic islets."These inflammatory monocytes are involved in almost every major disease," Nahrendorf explains. "Anti-inflammatory drugs currently on the market hit every inflammatory cell in the body, which can produce unwanted side effects. This new siRNA treatment doesn't affect inflammatory cells that don't rely on the CCR2 receptor. That makes a big difference."

CAPE TOWN, Dec. 15 (Xinhua) -- More people voluntarily get HIV tests in the Western Cape province, an indication of people's rising awareness of the epidemic, authorities said on Thursday.Nearly 11,000 people in the province have been tested over the past 10 days as authorities stepped efforts to halve the number of HIV transmissions over the next few years, according to official figures.Authorities expect more people to be tested when the monthly campaign ends by the end of December.In December last year, 67,111 people were tested.This year's figure is expected to be higher than that of last year, said Western Cape Premier Helen Zille.The campaign, known as Know Your Status and Win, may become a regular feature in the province, said Zille.To encourage more people to take part in the campaign, the province offers awards to several winners by drawing, ranging from 10,000 rand (about 1,250 U. S. dollars) to 50,000 rand (about 6, 250 dollars)."The bottom line is that people respond to incentives," said Zille, who hailed the campaign a success.She said the reality was that those who stubbornly did not want to get tested, were those crucially in need of doing so.While the data still had to be audited, preliminary results indicated a spike in the number of people who were tested.There was also a significant increase at routine testing center that were not part of the campaign, said Zille. Of 22.9 million HIV positive people in sub-Saharan Africa, 5.6 million in South Africa, according to an annual report by UNAIDS.

BEIJING, Jan. 1 (Xinhua) -- State Grid Corporation of China (SGCC), the country's largest power supplier, said Sunday it has put to trial operation a cross-border electricity transmission project in northeastern Heilongjiang province to supply Chinese with Russia's electric power exports.The electric power SGCC purchased from Russia began reaching Chinese customers late Saturday night after the completion of the direct-current back-to-back networking substation, or called "the trans-Amur project" by Russians, SGCC said in a statement on its website.The trial operation will last 168 hours, SGCC said in the statement.With a transmission capacity of 750 mega-watts, the electricity transmission project is China's biggest cross-border power line, according to SGCC."The implementation of the project will gain experience for the expansion of Sino-Russian energy cooperation and help promote the economic development for both countries," SGCC said.The project is also part of the Sino-Russian energy and trade cooperation.Russian Deputy Energy Minister Andrei Shishkin said in June 2011 that the transmission project would increase Russia's power supply to five or six billion kilowatt hours of electricity to China and Russia intended to increase its electricity supply to China in the coming years.Russian companies plan export 60 billion kwh of electricity to China by 2020. Power plants will be built along its border with China to reduce power transmission losses and reduce transportation costs.Also on Sunday, an oil pipeline linking Russia's far east and northeast China witnessed its one year anniversary of operation, as operators announced an accumulated 15 million tonnes of oil had been transported into China in 2011.

BEIJING, Dec. 20 (Xinhua) -- A senior Chinese official called for a higher level of requirements for promoting cultural and ethical progress at a national conference Tuesday.Li Changchun, a member of the Standing Committee of the Political Bureau of the Communist Party of China (CPC) Central Committee urged for efforts to "provide firm ideological assurance, powerful spiritual drive, effective media support and sound cultural conditions for achieving the great goal of building an overall prosperous society."Li, also director of the Central Spiritual Civilization Development Steering Commission, made the remark while addressing the National Award-issuing Conference on the Work of Cultural and Ethical Progress.Li Changchun (1st L), a Standing Committee member of the Political Bureau of the Communist Party of China (CPC) Central Committee and director of the Central Spiritual Civilization Development Steering Commission, presents the awards to the advanced collectives and individuals during the National Award-issuing Conference on the Work of Cultural and Ethical Progress held in Beijing, capital of China, Dec. 20, 2011. Li attended the conference on Tuesday and gave a speech.In his speech, Li extended his gratefulness to everyone engaged in cultural and ethical work at all levels, as well as to people from all walks of life for their active participation in, and support of, the work.Currently, publicizing the Party's new plenary session should be the primary task in cultural and ethical work, Li said."Cultural and ethical progress is a major component of the socialist cause with China's own characteristics," he said, emphasizing that substantial efforts must be made to strengthen Party leadership on the work.The meeting was presided over by Liu Yunshan, a member of the Political Bureau of the CPC Central Committee and deputy-director of the Central Spiritual Civilization Development Steering Commission.In an address at the gathering, he called for greater efforts in publicizing the models of cultural and ethical progress, so as to "enhance the level of civilization of the society as a whole."A total of 27 cities and municipal districts, 899 villages and small towns, and 1,794 institutions and enterprises were awarded for their marked achievements in cultural and ethical progress, and 23 cities and municipal districts that had been previously awarded were allowed to keep their honorary titles.

BEIJING, Oct. 6 (Xinhua) -- China's first space lab module were in good condition and all tests went on "smoothly" during the past week, according to a statement issued by the country's space project authorities Thursday.The unmanned module, Tiangong-1, or Heavenly Palace-1, blasted off on Sept. 29 from Jiuquan Satellite Launch Center in northwest China's desert area.Tiangong-1 switched to the orbit of 362 kilometers high and had orbited the Earth for 109 times by 6:00 p.m. Thursday, the statement said.Tests on the module's remote control system, video/audio equipments, temperature/humidity sensors, docking facilities and other functions had been conducted successfully, it added.It also revealed that the Jiuquan Launch Center and other units were preparing for the launch of the Shenzhou-8 unmanned spacecraft, which is scheduled to join the Tiangong-1 later this year.Shenzhou-8 and Tiangong-1 are expected to perform China's first space docking at a height of 340 kilometers above the earth's surface.