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Moderna announced on Thursday that it had enrolled 30,000 participants in its Phase 3 COVID-19 vaccine trial, with more than 11,000 of those participants from communities of color.More than 25,650 participants have already received their second vaccination, the company said in a press release.The company added that the study also includes 7,000 participants over the age of 65.“Completing enrollment of the Phase 3 COVE study is an important milestone for the clinical development of mRNA-1273, our vaccine candidate against COVID-19," said Stéphane Bancel, Chief Executive Officer of Moderna in the news release. "We are indebted to all of the participants in the study. We would also like to thank the investigators and our partners at clinical trial sites, including our partners from PPD and the NIH, as well as the dedicated Moderna team for their support in completing enrollment. Moderna is committed to rigorous scientific research and the highest data quality standards. We will continue to work in collaboration with regulators to advance mRNA-1273, which we hope will help defeat the COVID-19 pandemic.”CNN reported that for Moderna to apply to the FDA for emergency use authorization, the following three things need to happen:53 of the 30,000 participants would need to become sick with COVID-19, which is expected to occur in the second half of November.40 of the 53 participants who do become ill with COVID-19 need to have received the placebo, which would show that the vaccine is 75% effective.Make sure enough time has passed to see if participants develop side effects.According to CNN, Moderna is the first company to start US clinical trials of a COVID-19 vaccine. 1696
NASHVILLE, Tenn. – The second and final debate of the U.S. presidential election will be held at Belmont University in Nashville, Tennessee, starting at 9 p.m. ET on Thursday, Oct. 22.Originally, the Commission on Presidential Debates scheduled three forums between the candidates. The second debate, which would have been held town hall style, was canceled after President Donald Trump declined to participate when the commission announced the debate would be held virtually due to Trump's recent coronavirus infection.Who’s participating?The debate will be moderated by Kristen Welker, a White House correspondent for NBC News and co-anchor of “Weekend TODAY.” It will be Welker's first general election debate she has moderated, but she co-moderated the fifth Democratic debate during the 2020 primary season.President Donald Trump and former Vice President Joe Biden plan on participating in the debate. No other candidates, like Libertarian Jo Jorgensen, qualified to take part in the debate, based on the Commission on Presidential Debates’ candidate selection criteria.What will be discussed?The debate commission allows each moderator to decide which topics are discussed. Last Friday, Welker announced that the following topics would be addressed Thursday night: fighting COVID-19, American families, race in America, climate change, national security, and leadership.Earlier this week, Trump’s campaign manager, Bill Stepien, claimed the CPD had “promised” that Thursday’s debate would be about foreign policy and asked for Welker’s topics to be discarded. However, CPD responded and said “no debate in 2020 was ever designated by (the commission) as devoted to foreign or domestic policy."With that said, the president is expected to still grill Biden on his son Hunter’s business ties, as well as his foreign policy record in the Obama administration and as chairman of the Senate Foreign Relations Committee, The Washington Post reports.How will the debate be structured?After the first debate went off the rails, because the candidates constantly spoke over each other, the CPD announced changes Monday to “ensure a more orderly discussion.”As with the first debate, both campaigns have agreed to allow each candidate two minutes of uninterrupted time to make remarks at the beginning of each 15-minute segment of the debate. This time, however, “the only candidate whose microphone will be open during these two-minute periods is the candidate who has the floor under the rules,” the CPD said in a statement. Both mics will then be turned back on for an open discussion.What is being done to protect against coronavirus?The commission says Trump and Biden will again skip the traditional handshake before the debate starts and the audience will be required to wear masks.How can you watch?The debate will run for 90 minutes without commercial interruption. You can watch it live on our Facebook page, as well as on network and cable news channels.Where the race stands?Polls show Biden as the frontrunner in the national popular vote, leading most national polls by a 6 to 10 percent margin, but his margin in many battleground states is slimmer. Polls in a number of battleground states, such as Ohio, Iowa, Florida, and North Carolina, are within the margin of error, according to an aggregate of polls by Real Clear Politics. Biden is maintaining slight leads in Michigan, Pennsylvania and Wisconsin, which if he wins in addition to the states won by Hillary Clinton in 2016, would give Biden a victory. What’s next?All that will stand between Thursday's debate and Election Day is 11 days of early voting and the candidates' final appeal to voters. 3677
MIRAMAR, Calif. (KGTV) — University City neighbors are concerned with the F-35 coming to MCAS Miramar, saying it will be noisier and less safe.Tuesday night, a post on Nextdoor lit up talking about a fighter jet buzzing homes."When I hear the noise, I just think this is the sound of freedom. This is all about the sound of freedom, but I just also want to hear about safety and I'm not hearing the word safety," neighbor Don Hotz said.He's spoken with 10News before, concerned about flight paths Marines take. Several people have been emailing the base since September 2018, creating two binders full of papers. One concern points to a recent Environmental Impact Report draft by the Air Force, suggesting the noise from the F-35 could make neighborhoods in Idaho uninhabitable.Captain Matthew Gregory, MCAS Miramar director of communications, says the document remains unapproved and un-finalized. In Miramar, they've conducted several studies on noise and environmental impact, ensuring it is safe to bring the jets near the surrounding neighborhoods."On take off the F-35 is 2 decibels louder than the F/A-18 however when they're coming in to land, or in their normal flight, an F-35 is 10 or 11 decibels quieter so that's going to help in the noise reduction of the base," Gregory said. He added, over the next 10 years as the F-35 phases out F/A-18s and AV-8B Harriers, the base will get slightly quieter."The engine noise itself has a higher pitch, we're going to notice it a lot more even if it's quieter," Gregory said. He explained the higher pitch is due to a single technologically advanced engine.Neighbors are concerned a single engine plane is more dangerous. Gregory said there's nothing to worry about."It can be more reliable, it's going to cut down on maintenance costs because you're working on one engine instead of two engines. It's going to have increased range and potentially speed because it's lighter overall," he said.Gregory adds the base runs about a third as many aircraft a year compared to when the Navy operated the base. 2063
NATIONAL CITY, Calif. (KGTV) -- Police are looking for the driver of a BMW that crashed into a church fence in National City while attempting to escape a separate hit-and-run crash.According to National City police, it happened around 12:15 a.m. on Palm Avenue, leaving behind a trail of destruction in front of the church.Police say it all started when the BMW driver rear-ended a white Camaro at the intersection of Division Street and Palm Avenue. Moments later, the driver hit the gas trying to speed away from the crash but then hit another car, lost control, and crashed into a church fence.The BMW caught fire, but witnesses helped put it out before firefighters arrived.Witnesses say they saw a man and possibly one passenger running from the scene.No one was hurt.Police did find a shoe left behind at the scene and hope it will help lead to the suspect driver. 878
Myrtle Beach, South Carolina's police department is dealing with national scrutiny after police removed a man after he reportedly purchased a meal for homeless man inside of a McDonald's.The incident, which took place on Wednesday, was recorded on video, and has since gone viral, generating a national buzz. Nearly 40 million people have viewed the video in the 24 hours since it has been released. The incident happened after police were attempting to remove a man, who is reportedly homeless was eating a meal inside McDonald's. The man recording the incident claimed that he brought the man into the McDonald's and purchased him a meal."You guys suck... He didn't ask me for food, I saw him across the street and brought him over here for food," Yossi Gallo said. Gallo was then warned that he was being disorderly."I’m getting kicked out of here because I gave a homeless guy food,” Yossi Gallo said on the video he posted. Gallo and the homeless man were removed from the McDonald's by police. Police claim that the homeless man was asking people for money. A claim Gallo disputed. Myrtle Beach Police released a statement involving Wednesday's incident: Officers were dispatched to the location after receiving a call, from an employee of the business, that a male was in the parking lot asking people for money. Upon arriving at the restaurant, an employee approached the officer and indicated the male was inside the establishment. The employee requested the officer issue a trespassing warning and asked that the person leave the premises. The officer advised the male of the request made by the business and issued the warning. A bystander, who was videotaping the incident was also trespassed from the location, at the request of the manager, for what management deemed as disorderly behavior. 1858