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President Donald Trump has received at least eight different medicines and supplements since he was diagnosed with COVID-19.Several are new and approved under emergency or compassionate use orders, including Regeneron's antibody cocktail. It uses lab-created COVID-19 antibodies to boost the immune response.A late stage trial that has not been peer-reviewed yet suggests the cocktail is safe and appeared to reduce symptoms.“None of the other medicines that he's been given, whether it's Remdesivir, more recently, dexamethasone, none of them have actually been shown to have direct antiviral activity, that is, they don't lower the virus levels directly,” said Dr. George Yancopoulos, a founding scientist at Regeneron.Yancopoulos says they're getting more requests, but “compassionate use” is not intended for widespread distribution. The Food and Drug Administration would have to grant emergency use authorization“And as of course, we all know, when you're fighting a viral disease and it's a race between the virus taking over and your body beating it, and dropping viral levels would be a great indicator that that the battle is going in the right direction and that the patient is winning,” said Yancopoulos.The president also took a steroid called dexamethasone. It's used to treat inflammation and is proven to help people breathe when they need oxygen.“For patients who were hospitalized or getting oxygen, it was extremely effective in helping them walk out of the hospital under their own powers,” said Peter Pitts, President of the Center for Medicine in the Public Interest.Meanwhile first lady Melania Trump, who also tested positive, tweeted Monday that she is feeling good and will continue to rest at home. 1733

President Donald Trump is ready to oust Lt. Gen. H.R. McMaster and find a new national security adviser before the North Korea meetings in May, multiple sources told CNN Thursday.The move may be delayed because there's no final decision on a replacement, sources say. The timing of an announcement is unclear -- one source said it could come as soon as Friday, though others say that is unlikely.White House press secretary Sarah Sanders pushed back on reports that McMaster may be headed out the door in a tweet, saying,"Just spoke to @POTUS and Gen. H.R. McMaster - contrary to reports they have a good working relationship and there are no changes at the NSC."Any delay in the move is also because McMaster is trying to nail down his next steps, one of the sources said.The shake-ups come as Trump signaled this week that he's prepared to dismiss aides with whom he's clashed as he works to surround himself with advisers more aligned with his populist agenda and freewheeling style.On Tuesday, the President fired Secretary of State Rex Tillerson and told reporters at the White House he was near having his ideal team."I'm really at a point where we're getting very close to having the Cabinet and other things that I want," Trump told reporters on the South Lawn on Tuesday, moments after announcing Tillerson's firing.Amid speculation about McMaster's fate, CNN has reported that the three-star general has been in discussions with the Hoover Institution.As recently as March 8, the White House was denying reports that McMaster was on his way out, with Sanders declaring on "Fox & Friends" that "General McMaster's not going anywhere."Several sources told CNN that the push for a replacement comes after months of personal tension between McMaster and Trump.Trump has privately expressed irritation with McMaster stemming from differences in "personality and style," a senior Republican source said.The two have never gotten along, and Trump continues to chafe at McMaster's demeanor when he briefs him, feeling that he is gruff and condescending, according to a source who is familiar with his thinking.Sources with knowledge of McMaster's standing in the White House have repeatedly said that he has been on thin ice for months.There was discussion in the West Wing about replacing him last fall, but he ultimately survived because officials, including the President himself, were skeptical about the optics of appointing a third national security adviser in less than a year, several sources told CNN. Trump's first national security adviser, Michael Flynn, resigned within a month of taking the job amid controversy over his contact with Russian officials.McMaster was also retained at the time due to the White House's challenge attracting top talent for jobs in the administration due to Trump's "blacklist" of individuals who have criticized the President, his personality and the Russia investigation, according to a senior Republican source. 2990

PORTSMOUTH, Va.— A hit-and-run in Portsmouth, Virginia, left residents shaken up.Police say a driver hit a U.S. Postal Service letter carrier and drove off, leaving her in serious condition.Judi Gould was overcome with emotion Tuesday afternoon as a witness to the aftermath of a hit-and-run.“You can’t imagine what it’s like to see her like that,” said Gould.She says her beloved letter carrier was struck down in the middle of the street near Airline Boulevard and Caroline Avenue while delivering mail on her route.Police say the 44-year-old was crossing Airline Boulevard when she was hit by a vehicle just before 11 a.m.Police are looking for the driver of a black Dodge Journey that flagged down an officer about the crash. They are asking for the public to share any images from Alexander's Corner to Rodman Avenue between 10:45 a.m. and 11 a.m. Tuesday.The United States Postal Inspection Service is offering a reward of up to ,000 to anyone with information that could lead to an arrest.“She is like the most upbeat mail carrier. It was raining and she still was just glowing, just walking as fast as she could,” said Gould.She says it was only minutes after she saw her bubbly letter carrier that she heard the sirens.“The police were out there picking up all the mail and trying to gather it, and all you do is just watch them.”Gould watched nearby as first responders worked desperately to find signs of life.“They tried for the longest time to revive her. I’ve never seen them try so long and so hard, and she just wasn’t moving.”Multiple neighbors say the intersection at Airline Boulevard and Caroline Avenue is a trouble spot and say something needs to be done about cars flying through the area.“We need a light here we; really need a light here. If they don’t get a street light here, it’s gonna keep getting bad,” said Gould.Now, Gould is pleading for someone who may have details about the driver who left the scene or their vehicle to come forward.“I’m begging, somebody - please hold somebody accountable for this lady’s life, please.”In the meantime, she’ll be thinking of victim’s family, hoping they get closure before the holidays.“If you did it, and you know you did, it was an accident; please come forward. God forgives, and so do people. Just don’t be a coward.”This story was originally published by Kofo Lasaki at WTKR. 2362

POMONA (CNS) - A 38-year-old man was charged today with the murder of a 9-year-old girl whose body was found partially inside a large duffel bag near an equestrian trail in the Hacienda Heights area.Emiel Lamar Hunt -- who is believed to be the boyfriend of Trinity Love Jones' mother -- was arrested early Saturday in connection with the girl's death. Sheriff's officials said Hunt was found sleeping in his vehicle in a lot near San Diego International Airport. The arrest was assisted by the Port of San Diego Harbor Police. Hunt appeared briefly in a Pomona courtroom Tuesday, but his arraignment was delayed until April 16. He remains jailed in lieu of million bail.The criminal complaint alleges that Hunt has a 2005 conviction for child abuse from San Diego County. He could face up to 50 years to life in state prison if convicted as charged, according to the Los Angeles County District Attorney's Office.Sheriff's officials said earlier that two "persons of interest'' had been detained for questioning in the case, but only Hunt was charged Tuesday.Sheriff's officials said they were not disclosing any additional information about the second person of interest, pending further investigation. The victim's relatives told reporters the girl's mother was the second person beingquestioned, but sheriff's officials would not confirm those reports, and there is no record of her being arrested.County workers clearing some brush in the area found the girl's body found about 10 a.m. March 5. The girl was partially inside a black roll-away- type duffel bag, with her head and upper body protruding from the partially zipped bag left at the bottom of an embankment close to Colima Road and the 3400 block of Hacienda Boulevard, near the His Lai Buddhist Temple, authorities said.The coroner's office ruled her death a homicide, but officials have not said how the girl died.Sheriff's detectives initially asked for the public's help in identifying the girl, releasing a composite sketch of the child and photos of the clothing she was wearing. Family members who created a memorial of candles, flowers, balloons, stuffed animals and photos near where the girl's body was found eventually confirmed her identity."Words can't explain what I'm feeling right now,'' Anthony Jones, Trinity's father, said at the memorial site. ``I just want answers. I just want justice. She was just the best -- full of character, full of life, full of joy.''Jones said he learned of his youngest daughter's death through a telephone call. 2536

POWAY, Calif. (KGTV) — Poway will host two simultaneous Fourth of July fireworks shows this summer in order to encourage social distancing while continuing the tradition.Fireworks will launch from both Poway High School and Sportsplex in South Poway Business Park at 9 p.m. on July 4, the city says."Keeping these celebrations going is more important than ever," said Poway Mayor Steve Vaus. "They will bring people together in spirit and shine a little bit of light into the darkness we've experienced due to the pandemic, all while we celebrate our nation's founding."The two locations will allow for a nearly 360-degree view of fireworks from the Sportsplex while allowing those who traditionally view the show near the high school to continue doing so.However, there won't be any viewing allowed at Poway High School's football field due to public health orders. Instead, anyone who wants to view the show can purchase a parking pass to watch from across the street at Lake Poway. City officials say a map of the best viewing locations and more information will be posted online here soon.Anyone who heads out to view the shows is reminded to observe social distancing from groups that are not from the same household and wear facial coverings around non-household members. 1285