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SAN DIEGO, Calif. – What’s usually a marathon for biotech companies is now a full-blown sprint to stop the spread of coronavirus.Kate Broderick, the Senior Vice President of R&D at Inovio Pharmaceuticals in San Diego, remembers the moment she first learned about the mysterious outbreak unfolding thousands of miles away. “Yes, absolutely, distinctly, probably one of those moments you’ll remember forever. I was in my kitchen at home the 31st of December,” said Broderick.She never imagined that two months later it would be the crisis it is today. “Every week I keep thinking it’s going to get better, it’s going to start to tone down a little bit, but in fact, rather than getting better it’s getting worse every week,” said Broderick.Inovio has made headlines before, creating vaccines for Zika, Ebola, and now the coronavirus. After Chinese researchers shared the genetic sequence of COVID-19, Inovio designed a vaccine in just three hours Using its proprietary DNA medicines platform technology. The vaccine was designed to precisely match the DNA sequence of the virus“In an outbreak setting we really don’t have two to three years to wait for a vaccine, so that’s where we come in at Inovio pharmaceuticals, we use DNA medicine technology,” said Broderick.While traditional vaccines use the virus itself, this method puts DNA inside E.coli, which naturally replicates the medicine over and over. The paste is then purified, leaving behind only the DNA medicine, which Inovio hopes to test in humans next month.“Infectious diseases are global and they don’t care about boundaries and borders, everyone is affected from childhood all the way through seniors,” said Phyllis Arthur, who’s been in the infectious disease industry for 20 years.Arthur is Vice President of Infectious Diseases and Diagnostic Policy at BIO, an association made up of about 1,000 companies.“One of the things we’re seeing, from outbreak to outbreak, unfortunately, is we’re getting faster at using platform technologies to build something that can be tried in humans sooner than we were the last time,” said Arthur.She’s following dozens of companies working on vaccines, treatments, and diagnostic tools. If their vaccines work, companies like Inovio will have to figure out how to manufacture them fast.“You may have the best vaccine in the world, but if you can only produce 1,000 doses of it, that’s not really going to help 1.4 billion people in China,” said Broderick. Continued funding will also be critical. Broderick says while their Zika vaccine looked promising in humans, it never ultimately got FDA approval for broad public use.“The problem there was, although great for global health, was that of course cases of the virus really steadily declined, the problem for us there was so did the funding,” said Broderick.She says that way of thinking is shortsighted but does see change on the horizon. “It’s a huge amount of responsibility on everyone’s shoulders, and I think we feel genuinely compelled to do everything in our power, hence why no one complains about two hours of sleep, because this is a point in our careers we can truly, literally, make a difference in saving lives, right now,” said Broderick.After the company begins human trials in the U.S., they’ll continue testing in China and South Korea. They hope to deliver one million doses by the end of the year.If they make it that far, it too would be a day Broderick will never forget. 3462

Prosecutors in New York City hit indicted singer R. Kelly with new bribery charges Thursday that appear to be related to his 1994 marriage to a teenager.A revised indictment in federal court in Brooklyn accuses R. Kelly of scheming with others to pay for a "fraudulent identification document" for someone identified only as "Jane Doe" on Aug. 30, 1994. A day later, R. Kelly, then 27, married 15-year-old R&B singer Aaliyah D. Haughton in a secret ceremony arranged by Kelly at a hotel in Chicago. The marriage was annulled months later because of Haughton's age.Defense attorney Douglas Anton on Thursday called the latest charge against his client "ridiculous and absurd."The Brooklyn prosecutors had already charged R. Kelly with racketeering, kidnapping, forced labor and sexual exploitation. They alleged he and his employees and assistants picked out women and girls at concerts and groomed them for sexual abuse.The 52-year-old singer, who is being held without bond, is scheduled to stand trial in federal court in Chicago in April on child pornography and obstruction of justice charges before facing trial in Brooklyn. 1145

Prosecutors have offered to drop solicitation charges against Robert Kraft in unusual deal that calls for admitting he would've been found guilty 158

Social media platforms had a bit of a meltdown on Wednesday.Facebook, Instagram, WhatsApp and Twitter were all experiencing various issues.Users reported bugs, such as images not loading on Instagram and problems with Twitter direct messages, including the app showing notifications for unread DMs that weren't there when users checked their inbox."We're currently having some issues with DM delivery and notifications. We're working on a fix and will follow up as soon as we have an update for you. Apologies for the inconvenience," Twitter said in a tweet.Issues on Facebook and Twitter were happening in pockets worldwide, according to Down Detector, which tracks issues and outages on a variety of sites."We're aware that some people and businesses are currently having trouble uploading or sending images, videos and other files on our apps. We're working to get things back to normal as quickly as possible," a Facebook spokesperson told CNN Business, on behalf of its other apps Instagram and WhatsApp.It's unclear what caused issues on Twitter and Facebook apps. Facebook said it was investigating the problem, but noted it's not the result of a cyber attack. Twitter did not immediately respond to a request for comment.In March, Facebook was hit with a 1275

Roee and Adiel Kiviti have been married almost six years and live in the United States. They are both American citizens, as is their 2-year-old son, Lev. However, they say their infant daughter, Kessem, has been denied birthright citizenship under a State Department policy that considers her "born out of wedlock" — and they're not the first LGBT family to be affected by the policy under the Trump administration.Both children were born in Canada using an egg donor and a surrogate mother. The Kivitis told CNN's Brianna Keilar that it was "a straightforward procedure" to obtain Lev's US passport. This was not the case when they sought to do the same for Kessem in early May."We're a family of four people where three have American citizenship and a 2-month baby that the State Department is refusing her a right to a birthright citizenship," Adiel Kiviti said.The Kivitis said it initially seemed that their daughter's passport application would be processed under the policy for children born abroad of two US parents. However, they were later told her application had been flagged for surrogacy. Under the State Department policy on "assisted reproductive technology," "a child born abroad to a surrogate, whose genetic parents are a U.S. citizen father and anonymous egg donor, is considered for citizenship purposes to be a person born out of wedlock." When asked for comment on the Kivitis' story, a State Department official directed CNN to this operational guidance."We feel that it targets specifically LGBT families," Adiel Kiviti told Keilar on "CNN Right Now.""To be honest, when a straight couple is using surrogacy, or when a straight couple is using an egg donation or sperm donation, nobody asks them if they are the biological parents of the child, it's just an assumption. But when an LGBT family's coming and applying, our application was flagged as surrogacy."The Kivitis said they were asked to provide additional documentation like surrogacy and residency papers."Our position was and remains that we should be treated as a married couple and the minimal requirements that are in that regulation should be applied to us as well," Roee Kiviti told CNN in a separate interview. "Any additional requirements beyond that are discriminatory."He thinks they should be processed under INA301(c) which applies to US children born in wedlock to two US citizen parents.'This is an affront on American families'Roee Kiviti told CNN that it is not just LGBT families who should be concerned about the policy."I think especially after the Supreme Court ruling (legalizing same-sex marriage nationwide), there's no such thing as gay marriage. There's marriage. We are a family," he said."This is not an affront on LGBT families. This is an affront on American families, and it should worry everyone," Roee Kiviti said.A number of Democratic politicians have expressed outrage at the Kivitis' story, which was 2932