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A third leading candidate COVID-19 vaccine has entered a final stage of human testing in the United States. AstraZeneca announced Monday its potential COVID-19 vaccine has entered final trials in the U.S. to test the effectiveness and safety of the product. The Cambridge, England-based company said the trial will involve up to 30,000 adults from various racial, ethnic and geographic groups. The potential vaccine was invented by the University of Oxford and an associated company, Vaccitech.AstraZeneca said development of the vaccine known as AZD1222 is moving ahead globally with late-stage trials in the U.K., Brazil and South Africa. Further trials are planned in Japan and Russia.“To have just one vaccine enter the final stage of trials eight months after discovering a virus would be a remarkable achievement; to have three at that point with more on the way is extraordinary,” Health and Human Services Secretary Alex Azar said in a statement.Two other vaccine candidates began final testing this summer in tens of thousands of people in the U.S. One was created by the National Institutes of Health and manufactured by Moderna Inc., and the other developed by Pfizer Inc. and Germany’s BioNTech. 1215

A proposition on the November ballot would eliminate the state's ban on affirmative action when it comes to public hiring, contracting and college admissions.That means public agencies and universities can consider race, sex and ethnicity as it makes decisions, in an effort to address diversity.“I was able to go to Stanford and prove myself, and then go on to Georgetown and UCLA Law School on a full-ride scholarship, because I was given that initial opportunity,” Assemblywoman Lorena Gonzalez said Monday.Gonzalez said she was one of the last to benefit from affirmative action in California, because state voters banned the practice via prop 209 in 1996. She was speaking at a campaign event in favor of Prop 16, which would repeal the ban on affirmative action. Proponents say it would help level the playing and reduce the gender wage gap.“California’s ban on affirmative action programs has locked out small businesses owned by women and people of color from billions of dollars in contracting opportunities,” said Norma Chavez Peterson, who runs the ACLU of San Diego and Imperial Counties. “It has hurt students of color applying to both the Cal State and the UC California university systems, and it's limited access to good wages and benefits for many thousands of women and people of color.”Opponents say Prop 16 allows discrimination and that there's already assistance available for people who need a boost.“It's true that we need to do things to help people who haven’t gotten the same opportunities, but that's true whether they are African American, Latino, Asian, White, American Indian,” said Gail Heriot, a law professor at the University of San Diego who is co-chairing the No on 16 campaign. “We need to do things to help people that need a leg up, but let's not judge it on the basis of race.”State universities, for instance, can consider low income or being the first in a family to attend college in admissions decision making.Last week, our ABC-10news Union-Tribune scientific poll found Prop 16 leading with 40 percent in favor and 26 percent opposed, with the remainder undecided. 2119

A suspect wanted in the fatal shooting of a prominent Houston cardiologist is the subject of an arrest warrant, Houston police said at a news conference on Wednesday.Joseph James Pappas, 65, is the suspect, Chief Art Acevedo said. He has not been seen for the past two days, the chief said.Acevedo told reporters a tip came in Tuesday after surveillance video released a day before showed the suspect, whom someone said they recognized.The suspect's mother was a patient of the doctor and died during surgery 20 years ago, Acevedo said.Dr. Mark Hausknecht, who treated former President George H.W. Bush, was fatally shot as he rode to work at Houston Methodist Hospital on July 20.The renowned cardiologist and the suspect were seen shortly before the shooting riding their bicycles on South Main Street, police said. 825

A starting point for investigators trying to trace the bombs sent to Democratic figures and CNN this week: the postmark.But in some cases, it appears to be a missing clue.The postmark typically indicates when and where the mail was sent from and is marked over the stamps -- "canceling" them, and preventing the stamps from being reused. Unlike stamps, most of which cannot be traced, the impression left by a postmark or mail meter is distinctive and can help investigators focus their search.A postmark is visible in a photo of at least one of the packages seen by CNN. A postmark is not visible in photos of several other packages shared with CNN -- only adding to the questions about their origins.The lack of a postmark is very rare, according to Nancy Pope of the National Postal Museum.A postal inspector who spoke to CNN on the condition of anonymity indicated it would be very unusual for a piece of mail to leave the facility where it was dropped off for delivery without such a mark.That could indicate that a sender or senders were working in multiple diverse geographical areas, including New York, Washington, Florida and California.Another source told CNN it is possible some of the stamps may not have been canceled because of the package's soft sides and odd shape, which would make it difficult to stamp.The US Postal Service's website also says mail may not be postmarked if it was processed through a meter or if the postage was paid by permit or precanceled stamp. None of those appear to apply to this situation.Adding to the mystery are post office markings on one of two packages sent to former Vice President Joe Biden indicating the stamps on the package did not cover the cost of the delivery, and additional postage is due.That suggests the package was weighed at some point during the shipping process, a former postal inspector told CNN.It was unclear from the photo whether that package had been postmarked.Postmarks can be applied by machine and by hand, depending on how a piece of mail is sent, according to the Postal Service. When mail is run through an automated system at a processing distribution center, the postmark is applied, and the mailed item is screened by a biohazard detection system.It was not clear why postmarks were not visible on several of the packages, and the US Postal Inspection Service provided a statement to CNN that did not address the question."The U.S. Postal Service has developed a comprehensive approach to protecting the mailsystem by utilizing a targeted strategy of specialized technology, screening protocols and employee training," read the statement.The statement noted its Dangerous Mail Investigations Program includes law enforcement officers who "are trained to recognize the common characteristics of suspicious mail and are highly proficient in the use of state-of-the-art equipment to include portable X-ray machines." 2907

A South Korean army soldier patrols at the Unification Bridge, which leads to the Panmunjom in the Demilitarized Zone in Paju, South Korea. Tuesday, June 16, 2020. North Korea blew up an inter-Korean liaison office building just inside its border in an act Tuesday that sharply raises tensions on the Korean Peninsula amid deadlocked nuclear diplomacy with the United States. (AP Photo/Ahn Young-joon) 410

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