滨州羊癫疯治疗需多少钱(山东癫痫癫痫病哪家) (今日更新中)

WASHINGTON, Sept. 12 (Xinhua) -- An enzyme that appears to play a role in controlling the brain's response to nicotine and alcohol in mice might be a promising target for a drug that simultaneously would treat nicotine addiction and alcohol abuse in people, U.S. researchers find.Over the course of four weeks, mice genetically engineered to lack the gene for protein kinase C (PKC) epsilon consumed less of a nicotine-containing water solution than normal mice, and were less likely to return to a chamber in which they had been given nicotine. In contrast, normal mice steadily increased their consumption of nicotine solution while the mice lacking PKC epsilon did not.The study conducted by researchers at the Ernest Gallo Clinic and Research Center, affiliated with the University of California, San Francisco, appeared Monday in the online edition of the Proceedings of the National Academy of Sciences.In normal mice, as in humans, nicotine binds to a certain class of nicotinic receptors located on dopamine neurons, which causes dopamine to be released in the brain. Dopamine creates a feeling of enjoyment, and thus prompts a sense of reward. Researchers found that mice lacking PKC epsilon are deficient in these nicotinic receptors.The finding complements earlier research in which researchers found that mice genetically engineered to lack the PKC epsilon enzyme drank less alcohol than normal mice and were disinclined to return to a chamber in which they had been given alcohol."This could mean that these mice might not get the same sense of reward from nicotine or alcohol," said Gallo senior associate director and investigator Robert Messing. "The enzyme looks like it regulates the part of the reward system that involves these nicotinic receptors."The reward system is a complex of areas in the brain that affect craving for nicotine, alcohol and other addictive substances.The next step in the research, said Messing, would be to develop compounds that inhibit PKC epsilon. The ultimate goal, he added, would be medications that could be used "to take the edge off of addiction by helping people get over some of their reward craving."

BEIJING, Sep. 1 (Xinhuanet) -- Apple lost another iPhone prototype at a Bay Area bar, according to media reports Thursday.It is reported that an Apple employee lost a prototype iPhone at San Francisco bar Cava 22 in late July, which is a tequila bar in the mission district.A joint investigation by Apple and San Francisco police searched a local house but could not find it, the reports added.It seems that Apple employees learned nothing from last year’s lost iPhone scandal. A prototype iPhone 4 was lost in a Redwood City bar last year.Apple has denied any knowledge of the incident, and San Francisco police stated that Apple did not file a police report for the lost merchandise.If the reports are true, it would be a big blow to Apple’s ego since the company takes pride in its secretive nature.

UNITED NATIONS, June 9 (Xinhua) -- The message delivered by scores of speakers on the second day of the three-day UN High Level Meeting on AIDS on Thursday, marking 30 years of the pandemic, was that most of their countries were making progress but increased efforts had to be made with greater cooperation needed among nations.In the case of developing states, gratitude was expressed for past help but more aid was needed to continue the battle.Despite the similarities in content, the chair, UN General Assembly President Joseph Deiss, repeatedly appealed to speakers to limit their speeches to their allotted five minutes, warning at the halfway point that if everyone was taking an extra few minutes, a fourth day would have to be added to the agenda.One of the briefest addresses, well under time, was delivered by Yin Li, China's vice health minister, which he referred to as " a responsible developing country."Briefly listing some of the steps taken, the Chinese vice minister focused on achieving the UNAIDS goal of the three Zs -- " Zero new HIV infections, zero discrimination and zero AIDS-related deaths.""We should unite to generate a joint force, irrespective of gender, skin color, nationality, beliefs, values and ideology. Developed countries should further provide developing countries with unselfish, unconditional financial and technical support," he said. "Developing countries should place AIDS control in a position as important as economic development and actively explore prevention and treatment mode consistent with national conditions. ""Second, given the increasing disease burden of AIDS," he said, "the private sector and relevant organizations should shoulder more social responsibility."On the one hand efforts should be made to mobilize more resources in AIDS to better implement prevention, treatment and care measures; on the other hand, multinational drug manufacturers should reduce by a large margin the price of drugs, testing equipment and reagents through technology transfer, contract manufacturing and reduction of monopoly profits in order to promote universal access to treatment services," Yin added.Since AIDS prevention and treatment in China is an important component in the global fight against AIDS, he said, "Progress made in China is a positive contribution globally."The High Level Meeting on AIDS is taking place 10 years after the UN Special Session on HIV/AIDS and five years since signing of the Political Declaration in which UN Member States committed to universal access to HIV prevention, treatment, care and support.Norway's minister of the environment and international development, Erik Solheim, said, "Prevention and treatment must be mutually reinforcing and better treatment regiments need to be made available."He called for development of innovative methods for prevention.While Solheim said "remarkable" results had been achieved in the last three decades, there still was a need for a " transformation of current working methods."AIDS must be taken out of isolation into an "integrated approach," noting that HIV response has to be connected with UN Secretary-General Ban Ki-moon's Global Strategy for Women's and Children's Health and "HIV and AIDS programs should be mainstreamed into national health systems, he said.Solheim said that the social, political and economic empowerment of women is crucial and he welcomed the establishment of the new UN agency UN Women."The burden of HIV in the world is reduced but major challenges remain," the minister said. "Our experience is that the approaches that work well on HIV, are those based on rights and on promoting the dignity of people."Celsius Waterberg, the health minister of Suriname, said the nation "is among the few countries in the Caribbean where the incidence of HIV infection has decreased by more than 25 percent."The strides forward are due to a national multi-sectoral HIV Council, setting up structures to provide leadership in quality of services and training in revised treatment protocols, he said.Suriname, the smallest sovereign state in South America, on the northeast coast of the continent, also introduced combined prevention tools and implemented pilot projects successful in mobilizing men for circumcision as an additional preventive measure, Waterberg said.Challenges that need to be overcome include harmful traditions and customs, misconceptions and adverse beliefs, language barriers in a multilingual society and vulnerability of small communities and individuals due to HIV-related stigma, gender inequalities and poverty, he said.Victor Makwenge Kaput, health minister of the Democratic Republic of Congo, said that although the government had made progress in supporting individuals living with HIV and protecting the uninfected, it continues to face many challenges. Indeed, HIV prevalence stood at 3.7 percent for pregnant women and 3 percent for the general population, he said.AIDS' victims increasingly are women and youth with infections particularly concentrated along the Congo River, the minister said. Today, 1.2 million citizens are infected. Total population in the third largest country in Africa, about the size of Western Europe, is 71 million.He said women account for roughly 71,000 new infections each year and the government is now paying particular attention to mother-to-child transmission.Kaput said his long war-torn nation is committed to the global vision of zero infections and appealed for support to curb the spread of HIV.

BEIJING, August 23 (Xinhuanet) -- In the U.S., the rate of injuries related to children and teens falling out of windows declined over a 19-year period, although not nearly as fast as in some cities with comprehensive prevention programs, researchers found.From 1990 to 2008, the overall rate of injuries in children and teens was 7.3 per 100,000 per year, going as high as 11.4 in 1992 and as low as 5.8 in 1999, according to Gary Smith, MD, DrPh, of the Research Institute at Nationwide Children's Hospital in Columbus, Ohio, and colleagues.The annual rate of injuries fell slightly but significantly over the study period, driven entirely by a reduction of 0.426 cases per 100,000 per year in children up to age four, the researchers reported online ahead of the September issue of Pediatrics.That is much less than the reduction seen in previous studies of fall prevention programs in New York City and Boston, which achieved declines of up to 96 percent during a 10-year period through education, increased access to window guards, and a mandate to use window guards in certain homes (only in New York City)."The slower decrease followed by a plateau in injury rates found in this study underscores the fact that prevention efforts of the magnitude undertaken in New York and Boston have not occurred nationwide," Smith and hiscolleagues wrote.The researchers also acknowledged that the study underestimated the number of injuries related to falling out of a window because it included only those children treated in emergency rooms. An additional limitation is that the case narratives often lacked details about the circumstances surrounding the injury, including any suicidal intent.

SAN FRANCISCO, Aug. 2 (Xinhua) -- Social networking giant Facebook on Tuesday announced that it has bought Push Pop Press, a digital publishing company that develops the technology to help make interactive books optimized for iPad and other Apple devices."We're thrilled to confirm that we've acquired Push Pop Press, a startup whose groundbreaking software changes the way people publish and consume digital content," Facebook said in a statement.Push Pop Press was co-founded by Mike Matas and Kimon Tsinteris, both former Apple employees, and was known for teaming up with former U.S. vice president Al Gore to create a digital version of his book "Our Choice"."Although Facebook isn't planning to start publishing digital books, the ideas and technology behind Push Pop Press will be integrated with Facebook, giving people even richer ways to share their stories," Push Pop Press said in a statement posted on its website."With millions of people publishing to Facebook each day, we think it's going to be a great home for Push Pop Press," the statement added.Financial terms of the deal were not disclosed by the two companies.

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