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SANTA ANA (CNS) - Orange County health officials reported a record number of coronavirus cases for the second consecutive day Sunday, announcing 434 newly confirmed cases of COVID-19 and two additional deaths.The numbers bring the county's totals to 10,422 cases and 269 deaths, and follow Saturday's reporting of 413 newly confirmed cases and 10 deaths.The Orange County Health Care Agency said last week was the county's deadliest since the pandemic began, with 55 COVID-19 deaths reported between June 13-19.The number of people hospitalized with the coronavirus rose from 321 to 332, with the number of patients in intensive care dropping from 135 to 133.A total of 212,113 people have been tested for the virus, with 789 tests reported Sunday.There have been 4,953 documented recoveries, according to the OCHCA.The total number of Orange County cases break down to 50% men and 50% women, but men account for 57% of the deaths.Santa Ana leads all county cities with 2,189 cases, followed by Anaheim with 2,007. Their high numbers are attributed to large populations and the presence of multiple nursing homes in both cities. Santa Ana and Anaheim are Orange County's two largest cities in population.Dr. Clayton Chau, the Health Care Agency director and interim chief health officer, said the "hot spots" of Santa Ana and Anaheim "keep me up at night" with concern. He said about two weeks ago, a task force was formed among officials with the county and both cities to discuss ways to tackle the rising case counts. 1528
SAN YSIDRO, Calif. (KGTV)— November's violent clash between migrants and American border patrol agents temporarily halted businesses in San Ysidro. But many are saying it also has lingering effects on the tourism industry, both in San Diego and Tijuana.Sunday, Nov. 25, seemed like the beginning of the end for Wes Barba, the owner and operator of Baja Border Tours. The San Diego-based small group tour company specializes in day trips to Mexico.“It’s killing me. It’s really killing me,” West Barba said. “We go to Ensenada, Rosarito, and Tijuana, and the Guadalupe Valley for wine tasting."After the migrant caravan rush toward San Ysidro, Barba's phones have been ringing off the hook with last-minute cancellations.“They say ‘It’s going to be a problem coming back. Are we going to be in danger?’” Barba said. Each day trip, Barba usually has ten clients. Not anymore. With more clients canceling daily, he has no choice but to cancel the trips altogether.“10 customers to one customer. My profit went from 0 to zero a day,” Barba said. Barba said his counterparts in Mexico are also feeling the tourism lull. There are several reports of popular tourists areas in Rosarito, looking like ghost towns. Barba had no clients Sunday but still drove his tour van south of the border.“I have a great, great customer named Kathleen, and she put together her neighbors, and we put all the clothes together,” Barba said.Barba's customer inspired him and his family to gather clothes, shoes, and anything else he thought would help the migrants stuck in Tijuana. He put those donations into a suitcase and drove them to the migrant camps. He was struck by the conditions he saw first-hand.“Sleeping on the ground, under those tents. It gets me,” Barba said. Barba is fully aware that the recipients of his donations are the reason for his company’s dismal profits. But at the end of the day, he said his heart wins over his pocketbook. “Even though they are affecting our business, it’s not about ‘We hate you. You guys aren’t helping us. We’re not going to help you.’ No, it’s not like that. We actually want to give back also. Listen, we are all humans. We need to help each other,” he said. Barba is a proud U.S. citizen. He became one after he and his American wife escaped dangerous conditions in Colombia decades ago. Barba said he is sympathetic of the migrants but understands they need to go through the proper channels. In the meantime, he said he wants to help in any way. 2490

Scientists at the University of Nevada, Reno School of Medicine (UNR Med), led by its Nevada State Public Health Laboratory (NSPHL) are studying a likely case of COVID-19 reinfection.Forty-eight days after testing positive for SARS-CoV-2 in April 2020 and after testing negative consecutively twice, a Washoe County, Nevada patient tested positive again, in June.The patient had tested negative on two separate occasions in the interim. The genomes of the patient’s virus samples were sequenced in April and June, displaying significant genetic discordance between the two cases, implying the patient was infected twice.“We examined the genomic material of the viruses and samples to investigate this, says NSPHL Director Mark Pandori. “It is just one finding, but it shows that a person can possibly become infected with SARS-CoV-2 a second time.”To solidify confidence in the case, Pandori and the research team partnered with the Washoe County Sheriff’s Office Biology Unit to conduct identity testing on the specimens and lab samples evaluated in the study to verify the specimens were from the same person.Embedded in the genomic material of SARS-CoV-2 is a detailed code that Pandori says may provide insight to a better understanding of this virus.“A virus has a biological genome like all living things. Since March, the NSPHL has analyzed the genomic RNA of approximately 200 positive COVID-19 samples from Nevadans who have tested positive for COVID-19,” said Pandori. “The power of genomic information could turn the tables in the fight against the coronavirus.” The information is shared to a world-wide database known as “GISAID”,” alongside the work of thousands of researchers.According to Pandori and the NSPHL-led research team, reinfection cases are a potential warning sign that it is possible to catch COVID-19 more than once, and with unpredictable severity.“If reinfection is possible on such a short timeline, there may be implications for the efficacy of vaccines developed to fight the disease. It may also have implications for herd immunity,” says Pandori. “It is important to note, that this is a singular finding. It does not provide any information to us with regard to the generalizability of this phenomenon.”Herd immunity depends on the theory that after natural infection, our immune systems will collectively protect us as a community from reinfection and further spread. There are currently many more unknowns than knowns about immune responses to COVID-19. “After one recover from COVID-19, we still do not know how much immunity is built up, how long it may last, or how well antibodies play a role in protection against reinfection,” says Pandori.”While research and scientific advancements continue to build, Pandori says the hard work of fighting this pandemic together will continue through the use of facial coverings, hand-washing, social distancing, as well as wide-scale testing, contact tracing, and isolation of new cases.“This is a novel disease. We still have a steep learning curve ahead and lots of work to do, especially as inconvenient truths arise,” says Pandori.The NSPHL team are publishing their COVID-19 reinfection findings. Their report is publicly accessible on the SSRN preprint server, at https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3681489. This story was first reported by KTNV in Las Vegas, Nevada. 3384
SDCCU is proudly honoring local teachers through SDCCU Classroom Heroes, launched in partnership with iHeartMedia, Inc. San Diego. “SDCCU is engaged in many philanthropic activities aimed at making a difference in our local schools. We understand the critical role of teachers in helping to shape the future of today’s youth and contributing to a strong and thriving economy for years to come,” said SDCCU President and CEO Teresa Halleck. 452
SAN RAMON, Calif. (AP) — Business software pioneer Salesforce.com is buying work-chatting service Slack for .7 billion in a deal aimed at giving the two companies a better shot at competing against one of the industry's longtime powerhouses. The acquisition announced Tuesday is by far the largest in the 21-year history of Salesforce, a San Francisco company that was one of the first to begin selling software as a subscription service that could be used on any internet-connected device instead of the more cumbersome process of installing the programs on individual computers.According to the Associated Press, Salesforce purchased data analytics specialist Tableau Software for .7 billion last year.The company’s current market value is 0 billion, the AP reported.The AP reported that both companies are located about a block away from each other in San Francisco. 886
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