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SORRENTO VALLEY, Calif. (KGTV) - Another San Diego-based company is moving forward on developing a vaccine for the coronavirus. Sorrento Therapeutics is working on several projects that they believe could lead to viable vaccines or treatments. One of them was announced on Monday. Sorrento Therapeutics said it was partnering with Boston-based Smartpharm to create a gene-encoded antibody vaccine. “In the effort to more quickly resolve the global COVID-19 crisis, our company has initiated a rapidly accelerated program for the identification of potent neutralizing antibodies against SARS-CoV-2 coronavirus antigens that may be used for either treatment or prophylaxis,” said Henry Ji, CEO of Sorrento Therapeutics. Sorrento Therapeutics is also working on another vaccine called the I-Cell project. That vaccine uses a decoy virus to activate a person’s immune system to train it to attack the real virus. It’s also developing a protein called COVIDTRAP that can bind to the receptors on the coronavirus, thus blocking it from being able to bind to the receptors on healthy human cells. If proven succesful, it could be used as a treatment or preventative measure.How long will it take for them to be ready?“That all depends on what leeway the FDA gives us,” said Mark Brunswick, Senior Vice President of Regulatory Affairs at Sorrento Therapeutics. If they can get fast tracked, he estimates they can start clinical trials in 2 months, as opposed to 9-12 months normally. 1483
SIOUX FALLS, SD — New DNA technology has led to the arrest on Friday of a South Dakota woman who is being charged with murder for allegedly leaving her newborn in a ditch 38 years ago, according to police.On Feb. 28, 1981, a full-term baby boy was found in a blanket in the cold in Sioux Falls, police said. The baby had been born alive, but died from exposure to the elements, a coroner said, according to Sioux Falls police.No suspects or family members were identified, police said. A cemetery interred the baby and give him the name of Andrew John Doe, police said.After nearly four decades on Friday morning, the baby's mother, 57-year-old Theresa Bentaas, was arrested and accused of leaving the baby alive in the ditch, Sioux Falls police said at a news conference. She was charged with first-degree murder, second-degree murder and first-degree manslaughter, police said.The baby's father was also interviewed, but not arrested because "it was determined that at that time they were young teenagers and he did not know," Sioux Falls police Detective Michael Webb said.The cold case first heated up 10 years ago as DNA technology advanced and investigators looked into obtaining DNA from the unidentified baby, Webb said.In 2009 the baby's body was exhumed and his DNA was put into databases, but over the years there were no matches, Webb said.Then in April 2018, Webb said the arrest of the suspected "Golden State Killer" piqued his interest.The alleged "Golden State Killer," a serial killer and rapist who terrorized California in the 1970s and 1980s, became the first person to be publicly arrested through genetic genealogy. Genetic genealogy takes an unknown suspect's DNA from a crime scene and identifies the suspect through his or her family members, who voluntarily submit their DNA to genealogy databases.Since April 2018, genetic genealogy has helped identify more than three dozen suspects, according to CeCe Moore, chief genetic genealogist for Parabon NanoLabs, which has worked on the majority of the cases, including Andrew John Doe.Parabon helped Sioux Falls investigators build a family tree based on the baby's DNA, and they combed through old birth and marriage announcements to help put the pieces together, Webb said.A possible match was found in February 2019. The suspect, Bentaas, still lived in Sioux Falls and police executed a search warrant to get her DNA, police said. DNA tests then confirmed Bentaas was the baby's mother, police said.The baby's father was also still living in Sioux Falls, Webb said."We did interview them last Wednesday on the anniversary that we believe the baby was put in the ditch, on Feb. 27," Webb said. "It was confirmed that the baby was theirs."Bentaas is scheduled to appear in court on March 11. Her public defender declined to comment to ABC News Friday."It was sheer determination and stubbornness coupled with science and DNA and genealogy that solved this," Webb said. "All these cold cases and these children, victims of homicides that are being solved nowadays, including the Golden State Killer...just keep pushing, because that new advancement is right around the corner. It's pretty amazing." 3181

Small businesses employ roughly half of all Americans, but new data is showing many of these businesses are closing permanently.“It’s an excruciatingly hard decision,” said Martha Studstill. “You know small business owners put their heart and soul into their business.”For more than a decade Studstill has owned a small gift shop, Uptown Gifts, in South Carolina.“Until COVID came along we were buzzing,” said Studstill.Originally, in March, the plan for Uptown Gifts was to close temporarily for a few weeks. However, the shop has now been closed for more than three months. She has only been able to list items online, resulting in sales being down by 75%.However, sales aside and more importantly to Studstill, the danger of COVID-19, especially for someone her age, hasn’t subsided.“When we closed on March the 16, I really had no idea we would be where we are at today,” said Studstill.Studstill thought she would be reopening, not only earlier, but to fewer cases of COVID-19.Cases have actually been on the rise in her state. The uptick started most distinctly after reopenings. So, with the financial risk and uncertainty added to Studstill’s health risk of running the shop, she feels closing is her only choice.“I think if I were younger, I would not have made the same decision, but I am where I am at,” she added.Around the country, there is a wave of permanent business closures happening. One report done by Yelp shows more than 143,000 businesses listed on its platform closed between March and June. Now, roughly 35% of those businesses have indicated their closures are permanent. Most of those businesses closing are small businesses.“The numbers that are coming out are really sad,” said Frank Knapp with Small Business for America’s Future.Knapp heads the newly formed organization, pushing for better help for small businesses in Congress’ next stimulus package.“Our proposal for Small Business for America’s Future is that we need to put together grants for the really small businesses to help them get through this recession so that they are healthy on the other side and our economy can get back up and running again,” said Knapp.Saving small businesses could save jobs and be the fastest way to rebound the economy.“Small businesses hire about 50% of all workers in this country,” said Knapp, “We know from the last recession, it was small businesses that got us back on our economic feet again, not big businesses. Small businesses did the hiring right away.”“I think that this could be a defining moment where the general public could see just how important small businesses are to their community,” added Studstill. 2651
Special counsel Robert Mueller's investigators have questioned a Russian oligarch about hundreds of thousands of dollars in payments his company's US affiliate made to President Donald Trump's personal attorney, Michael Cohen, after the election, according to a source familiar with the matter.Viktor Vekselberg, chairman of asset manager Renova Group, is an oligarch close to Vladimir Putin, and last month the Trump administration placed him on a list of sanctioned Russians for activities including election interference. The purpose of the payments, which predate the sanctions, and the nature of the business relationship between Vekselberg and Cohen is unclear.The scrutiny of the payments could add to the legal troubles for Cohen, whose home and office were raided last month as part of a criminal investigation by federal prosecutors in Manhattan. In court documents, the prosecutors said at least part of their inquiry stemmed from a referral from Mueller's office.The questions asked of Vekselberg suggest that Mueller investigators have been examining some of Cohen's business relationships as part of the investigation into Russian meddling in the 2016 presidential election. Vekselberg is one of two Russian oligarchs the FBI stopped earlier this year after their private jets landed in New York-area airports as part of Mueller's investigation.Investigators also asked Vekselberg about donations the head of his US affiliate made to Trump's inaugural fund and campaign funds, sources said.The attorney for Stormy Daniels -- the porn star who received 0,000 to keep quiet about an alleged affair she had with Trump a decade ago -- produced information Tuesday evening that appears to add further details to CNN's reporting. Michael Avenatti alleged that Cohen received half a million dollars from a company affiliated with Vekselberg in the months after the presidential election.Avenatti alleged the 0,000 went into the bank account for Essential Consultants, a shell company that Cohen set up before the election that was used to pay Daniels. Avenatti added that the payments occurred from January to August 2017.CNN has reviewed documents that appear to show these payments. CNN has not independently authenticated the documents.Prosecutors have not accused Cohen of wrongdoing in regard to the payments or any other business dealings. 2366
Starbucks announced in a press release Tuesday that it will close 8,000 company-owned stores in the United States on May 29 in order to provide its staff with mandatory racial-bias education.The stores will be closed during afternoon hours that day. At that time, employees will be required to attend a training session that will address "implicit bias, promote conscious inclusion, prevent discrimination and ensure everyone inside a Starbucks store feels safe and welcome."The press release states that the program will be developed with "national and local experts on confronting racial bias," along with NAACP officials and former Attorney General Eric Holder.The announcement comes just days after two black men were arrested at a Philadelphia Starbucks. The police were called because the men chose not to order anything. The men were later released when the company chose not to press charges.Starbucks CEO Kevin Johnson apologized for the arrest on Monday, calling the situation "reprehensible.""Starbucks stands firmly against discrimination or racial profiling," Johnson said. 1109
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