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SAN DIEGO (KGTV) -- California state officials have issued their COVID-19 guidelines for gathering during the holidays. With less than two weeks until Thanksgiving, the guidelines include things like physical distancing and wearing a mask when not eating or drinking. There are specific guidelines for counties in the purple tier, like San Diego County. Counties in the purple tier are required to gather outdoors. Health officials recommend no more than three households and limiting the gathering to two hours or less. Infectious disease specialists say the guidelines are strict, but necessary to slow the spread of the virus. Other recommendations include having guests frequently wash their hands and having only one person serve food and beverages, with a mask on. Older and at-risk individuals are advised not to attend. To read the full list of recommendations click here. 889

SAN DIEGO (KGTV) — As the coronavirus pandemic has left many San Diegans in need.From hospitals to food banks to neighbors, there are plenty of ways to lend a hand.HOW TO HELPHospitals: Many local hospitals are reeling from the coronavirus pandemic, mainly with a lack of personal protection equipment. One way to support hospitals is to donate gear. Many San Diego hospitals are accepting donations for masks, gloves, eye wear, hand sanitizer, food, money, and more to support the health care industry at this time. LinkMany have also started making masks for health care workers. To help contribute, find out more.Blood donations are also in critical need. To donate blood, visit the Red Cross San Diego or San Diego Blood Blank.Seniors: There are a number of ways to help out local seniors who are under self-isolation during the coronavirus pandemic. One of the easiest ways is logging on to NextDoor and connecting with neighbors to talk or help out if they need a hand. LinkIn San Diego, locals can also help out Serving Seniors, a non-profit that delivers meals to low-income seniors, by making a dontion. LinkFood: Local food banks are also in need of support — food, money, and volunteers — to response to needy San Diegans during the COVID-19 pandemic. To make a donation to the San Diego Food Bank, click here.Restaurants: Local restaurants are some of the hardest hit businesses during the coronavirus pandemic. A simple way to help them out is to continue supporting them. The #TakeOutChallenge supports the campaign to continue eating at local establishments. LinkAs part of 10News' We're Open San Diego initiative, you can search for businesses that are remaining open and continue lending your support during this tough time. LinkSmall businesses/Nonprofits: The San Diego Foundation has set up a Community Response Fund to help local nonprofits, who can in turn support small businesses and individuals affected by the coronavirus. Individuals, businesses, and foundations can make monetary contributions to support the fund. To make a contribution, click here. 2086

SAN DIEGO (KGTV) - Anyone touched by Alzheimer's knows how painful the disease is. "It's affected my family. It's affected most families. It's such a prevalent disease. As people get older, it becomes quite likely this will become an issue," said Paul Aisen, director of USC's Alzheimer's Therapeutic Research Clinic (ACTC).Aisen's team began their research in San Diego many years ago and teamed up with USC about four years ago. He's spent over 30 years trying to solve Alzheimer's mysteries and is leading the upcoming clinical trial.Aisen says the large-scale study is the culmination of decades of work from scientists worldwide."Our focus lately has been trying to alter the disease, prevent it, or significantly slow its progression. How should we do that? We think attacking amyloid early is the most promising approach," said Aisen. Researchers believe sticky amyloid deposits, which form on the brain later in life, start the Alzheimer's process. Aging, genetics, and lifestyle factors can all contribute to amyloid build-up.The worldwide clinical trial aims to target amyloid. A drug called BAN2401 will be delivered intravenously, designed to bind to the sticky amyloid. The binding neutralizes beta amyloid and helps "tag" it, so the immune system can recognize it and clear it from the brain. A previous phase 2 study showed that BAN2401 removes brain amyloid and possibly slows cognitive decline.They're seeking participants over 50 who are not yet showing symptoms of Alzheimer's but do have elevated amounts of amyloid on their brain. Researchers can determine that through a PET scan or spinal tap. "We think that the most promising approach of all is to take a vigorous attack on amyloid while the brain is still functioning normally. And we can see amyloid in people many years before they develop the symptoms of Alzheimer's."Investigators hope that by treating a patient with BAN2401 very early in the disease, before symptoms occur, it will significantly slow disease progression. "If we're successful, it will have a huge impact on human health," said Aisen. There will be 100 sites worldwide for the study, including major cities like San Diego and Los Angeles. Study participants will receive treatment for four years, given either the drug or a placebo. Results are expected in seven years, Aisen says. If you or a loved one wants to participate, learn more here.Screening will officially begin in May. 2438

SAN DIEGO (KGTV) - County officials created a Dia de los Muertos altar to honor the lives of 891 San Diegans who died from the coronavirus, and put a face and heart into the fight.Supervisor Nathan Fletcher and Assemblywoman Lorena Gonzalez championed the altar as a way to send a message."We wanted to honor those families and honor those lives lived and acknowledge the tremendous impact it's had, but also pay particular tribute to the impact that covid has had on the Latino community," Fletcher said.Saying more than half of those who died in the county are Latinos. This is extremely disproportionate considering only 30% of the population is Hispanic, according to the 2019 Census."When we start looking at the actual human toll and our relatives who have moved on now as a result of this virus it becomes more real and reminds us why it's so important to stay so vigilant," Gonzalez said.Vigilance is what Treasure Felder said would have saved her mom Ronda."She was our angel on earth and is now our angel in heaven, that's how we like to refer to her," said Felder. Felder says her mom was a social worker with the county, caring for foster youth and a strong woman in her 60s."She was never really ill, in the hospital, or hurt. Even if she had a little pain she'd always push through. So to see her in a place where she could barely stand up and also having to be put in a chemically induced coma was something that none of us prepared for." she said.She said she walked into her mother's room on July 4th and found she couldn't stand and was breathing heavily. She called an ambulance, even though her mother didn't want to go to the hospital, and never saw her again.Felder said her mother always had her hand out to help others and is so incredibly proud of how her mother led her life. She hopes sharing her story of pain and emptiness, now that her mother is gone, will stir others to take steps like wearing a mask and social distancing to stop the spread of the coronavirus.The altar will stay up through Tuesday morning. 2048

SAN DIEGO (KGTV) - Community leaders and the city have set up a truce over a makeshift pump track in on Famosa Boulevard near Nimitz Boulevard in Point Loma.  181

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