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SAN DIEGO (KGTV) - Like Pfizer, Moderna, AstraZeneca, and many others, INOVIO Pharmaceuticals has also raced to develop a COVID-19 vaccine this year.“We’ve been working really hard to move our vaccine through the stages of clinical testing. Some things have taken a little bit longer than we hoped. I think that’s kind of always the case when you’re trying to go at great light speed,” said Dr. Kate Broderick, INOVIO Pharmaceuticals Senior VP of Research & Development based in San Diego.Broderick said with funding from the U.S. Department of Defense, the biotech company started its Phase 2 clinical trial evaluating its DNA vaccine candidate, INO-4800.The first U.S. participants received a dose of the experimental vaccine earlier this month. Approximately 400 adults in the U.S. are expected to be enrolled in the trial by the end of the month.“We hope that in the early part of 2021, we’ll be going into a really large Phase 3 trial where we’re asking the question does our vaccine protect against the disease itself,” she said.Broderick said the company hopes to enroll about 6,000 participants initially in its Phase 3 trial once they get the green light to begin.A press release from the company last week stated that “The Phase 3 segment of the INNOVATE remains on partial clinical hold until INOVIO satisfactorily resolves the FDA’s remaining questions related to the CELLECTRA 2000 device that will be used to deliver INO-4800 into the cells of the skin.”Earlier data released from Pfizer and Moderna’s studies showing high vaccine efficacy was positive news for INOVIO.“We feel that we’re in a really good place. There’s eight billion people on the planet, and we’re certainly going to need quite a few different types of vaccines to ensure everybody is protected,” she said. “The Moderna and Pfizer vaccines are RNA vaccines; ours is DNA vaccine”Broderick said one significant benefit of INOVIO’S DNA vaccine candidate is it doesn’t have to be stored in low-temperature freezers, making it easier to ship out worldwide if approved.“In fact, we can keep it at room temperature, sitting on a desk somewhere for a year with no impact,” she said.INOVIO is projecting to have 100 million doses of its vaccine ready in 2021.“With these vaccines being approved, there is definitely an end in sight, but don’t let your guard down too fast,” she said. “Unfortunately, until everyone in the country gets vaccinated, we will still have to adhere to those kinds of annoying things, wearing masks, socially distancing. I know it’s frustrating, especially before the holidays, but just keep yourself safe and the people you love safe.” 2648
SAN DIEGO (KGTV) — Just a few weeks ago, coronavirus testing was hard to come by. But now, many San Diegans are finding it easier to get tested. Some are purchasing at-home test kits online, at no up-front cost.Raechel Kadoya is not a clinician, nor is she at a doctor's office. She is the co-owner of Soichi Sushi, giving herself a COVID-19 test."I want to take advantage of being proactive," Kadoya said as she swabbed her nose.Since the modified re-opening of her restaurant in University Heights, she and her staff have been cautious about coronavirus exposure. That is why she ordered the Pixel by Labcorp at-home COVID-19 test kit for her entire staff."I think that it is my responsibility as a business owner, not only to my staff but to my customers and my family, to make sure that everybody is doing business here safely," Kadoya said.This is the staff's second round of testing. Kadoya said the first one required multiple doctors referrals just to get a drive-through appointment an hour away."We were able to find a place in Lake Elsinore, so we all had to drive up there," Kadoya said.Dr. Abi Olulade, a family medicine physician at Sharp Rees-Stealy Medical Group, said the accessibility of these at-home tests is a big draw."It definitely is something that is very convenient for consumers," Dr. Olulade said.But she suggested customers do their homework before they order."They should be looking at whether or not the tests that they are using have been FDA authorized, and it's not just some random test that they found on the internet," Dr. Olulade said.As of June 12, 2020, seven at-home COVID-19 test kits have the FDA's emergency use authorization. They are:Phosphorus DiagnosticsPrivapathP23 LabsEverlywellRutgers University LabQuest DiagnosticsLabcorpTo get this authorization, the FDA requires at-home tests to have 95% accuracy in detecting positive results and 100% accuracy in detecting negative results.Insurance covered the upfront costs for Kadyoa's staff. But for those without insurance, some tests are covered by federal funds.From an accessibility and affordability stand-point, Kadoya said this is what works best for her."I want to do this every couple of weeks as maintenance," Kadoya said.Dr. Olulade also said to make sure the labs doing the testing also have CLIA certification, which sets national standards for accuracy, quality, and reliability. 2397
SAN DIEGO (KGTV) — Max may look like most 5-year-olds, but a rare illness left him paralyzed from the shoulder to his wrist. Bending his arm on his own is impossible — until he puts on a new device designed to help him move.University of California, San Diego, engineering students Ethan and Marcos Serrano developed these "Iron Kid" arms over the last ten weeks after max's doctor at Rady Children's Hospital enlisted their help. Today is the first time Max and his family will be able to take the arms home. Dad, Ted Ng, says he and his wife have been in awe of this whole process."It's been really touching to have this come together," Ng said. "There's all kinds of robotic arms out there but none of them would really work for his condition."Grateful to see their son gain back some of his mobility. "It was kinda of like a miracle cause I didn't know how well it would work on him cause because as a child his limbs have a very specific shape," Ng added.And do more of the stuff 5-year-olds do, like pick stuff up, eat his favorite foods, or just play with his dad."It's really up to him to figure out how he wants to use this thing," Ng said. 1158
SAN DIEGO (KGTV) -- In 2014, the Whittingtons shared their story about their first-born child in a video that went viral.Ryland was born a girl. “As soon as Ryland could speak, she would scream, ‘I am a boy!’” the video explained. As Ryland got older, the feelings got stronger.After consulting professionals and experts, parents Jeff and Hillary Whittington came to the conclusion Ryland was transgender. For their child’s well-being, they decided to allow him to transition as soon as possible.Today, the YouTube video about Ryland's journey has more than 8 million views.In a 2016 interview with 10News, Jeff Whittington explained some of the criticism his family received. “They think that this is something that just happened overnight. We just made this split-second decision and our son said, ‘I feel like a boy.’ And we said great. And that wasn’t the case,” he said.Hillary Whittington wrote a book about their journey, Raising Ryland."I think people are definitely opening their minds a lot more,” Hillary Whittington said, as she reflected on their family’s journey over the past several years.Jeff explained how they try to deal with those who do not agree with their family’s decision. “We recognize that a lot of that comes from background, stories, and experiences they’ve had. We tend to take that negativity and try and understand what the source of that may be and try and find empathy for those that are critical,” he said.Ryland, now 12-years-old, said he is comfortable with his story being so public. “I know it helps a lot of people,” he said.Last year, his family hosted a “coming out party” to share with loved ones. Ryland gave a speech in front of his friends and others close to him. “It’s not a secret, but for many years I’ve kept it private because I was afraid you might treat me differently or not look at me the same if you knew,” he said. “When I was born, the doctors told me that I was a girl. But they were wrong. In my head and in my heart, I’ve always been a boy.”Ryland is about to enter seventh grade. He loves math and sports—his favorites are ice hockey and lacrosse.He shared what Pride month means to him. “Pride month is just a month of showing who you are and showing that you support who people want to be,” Ryland said.“We’re grateful for who our kids are. They’ve taught us so much about life and I wouldn’t a thing about them,” Hillary said.For those who still have negative things to say about their family, Ryland’s 8-year-old sister shared her thoughts. “I would want to say to them that I don’t care what they think and that I am happy to be who I am and who my family is,” Bryn said.“She took the words right out of my mouth!” Ryland echoed. 2706
SAN DIEGO (KGTV) — Looking for dinner with a view?In San Diego, the best views are found up and down the county's coastline, according to OpenTable users. The dining website's rankings were pulled together 12 million reviews for more than 28,000 U.S. restaurants collected on OpenTable between June 2017 and May 2018.In San Diego, 10 restaurants took honors as one of the best places to grab something to eat that's just as beautiful as the scenery nearby: 479