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that killed more than 30 people in Ohio and Texas.The former vice president and 2020 Democratic presidential candidate declared in an 134

Supporters of right-to-try argue that the legislation is needed because most terminal patients are too sick to be selected to participate in clinical trials and it takes too long for promising treatments to be approved.Joffe argued that the right-to-try approach to providing access to unapproved drugs early in their development could put patients in harm's way, as patients receiving the drug are often in very fragile health, doctors often lack the information needed to administer the drugs safely, and little may be known about their risks and benefits, he said.Joffe pointed to certain stem cell therapies as treatment approaches that appear promising but have turned dangerous when unregulated."Another thing I'm worried about is that there's going to be a bunch of shady actors that are going to pop up that are going to start to try to take advantage of the right-to-try law to say 'we can provide these sort of experimental therapies, if you want to call them that, to patients without needing to go through the FDA,'" Joffe said."We've already seen some of that in the stem cell clinics popping up around the country that try to provide stem cell treatments for a host of problems: eye problems, heart problems," he said. "While there are legitimate efforts to develop effective stem cell therapies, a lot of these clinics that are popping up around the country that are poorly regulated are taking people's money and they are hurting people."On the other hand, the treatments available under right-to-try laws are already in clinical trials, Coleman said, adding that "this law isn't replacing the existing FDA expanded access program; it's just opening up another avenue.""No person is going to be forced to take an investigational drug. No doctor is going to be forced to request an investigational drug, and no drug company is forced to provide an investigational drug, if they don't think it's the right fit for a patient," she said."It's only for people who say, 'I understand the risk. I know this drug is not fully approved. It may not help me, but my doctor and the drug company think it could, and I want to try,'" she said. "Basically, if the FDA says that a drug is safe enough to be used in trials on humans, then it's safe enough for a dying person to make their own choice about whether or not they would like to try it when they can't get into a clinical trial."  2395

Suspect Robert Bowers faces 29 federal charges, including counts of hate crimes that are potentially punishable by death. He made his first court appearance Monday.Bowers was detained without bond and his next court date is Thursday. The US attorney in Pittsburgh has started the process of seeking the death penalty and the state plans to file its own charges later.Pennsylvania Attorney General Josh Shapiro said his office is looking into whether Bowers and others used social media platform Gab to incite violence based on evidence that the suspect posted anti-Semitic comments on the site. 599

Smoke is expected to be visible throughout the day in various rural East County communities, including Julian, Palomar Mountain and Warner Springs. 147

Southwestern College is surveying its graduating class for input on commencement, be it a virtual celebration or postponement to a later date. A decision is expected to be announced by April 10. All other events and ceremonies are canceled at all Southwestern College campuses, including the Crown Cove Aquatic Center.The Southwestern College Foundation, in partnership with the Southwestern College Board of Trustees, has launched an SWC Cares Emergency Campaign to assist students in need. Updates can be found through the college’s Special Health Updates web page. 567